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Mechanography
Mechanography (also referred to as ''jumping mechanography'' or ''Muscle Mechanography''Taani MH, Kovach CR, Buehring B: ''Muscle Mechanography: A Novel Method to Measure Muscle Function in Older Adults.'', Res Gerontol Nurs, 10(1):17-24, 2017; ) is a medical diagnostic measurement method for motion analysis and assessment of muscle function and muscle power by means of physical parameters. The method is based on measuring the variation of the ground reaction forces over the time for motion patterns close to typical every day movements (e.g. chair rise or jumps). From these ground reaction forces centre of gravity related physical parameters like relative maximum forces, velocity, power output, kinetic energy, potential energy, height of jump or whole body stiffness are calculated. If the ground reaction forces are measured separately for left and right leg in addition body imbalances during the motions can be analysed. This enables for example to document the results of therapy.Fric ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mechanostat
The Mechanostat is a term describing the way in which mechanical loading influences bone structure by changing the mass (amount of bone) and architecture (its arrangement) to provide a structure that resists habitual loads with an economical amount of material. As changes in the skeleton are accomplished by the processes of formation (bone growth) and resorption (bone loss), the mechanostat models the effect of influences on the skeleton by those processes, through their effector cells, osteocytes, osteoblasts, and osteoclasts. The term was invented by Harold Frost: an orthopaedic surgeon and researcher described extensively in articles referring to Frost and Webster Jee's ''Utah Paradigm of Skeletal Physiology''Frost H.M.: ''The Utah Paradigm of Skeletal Physiology Vol. 1'', ISMNI, 1960Frost H.M.: ''The Utah Paradigm of Skeletal Physiology Vol. 2'', ISMNI, 1960 in the 1960s. The Mechanostat is often defined as a practical description of Wolff's law described by Julius Wolff (1836– ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Motion Analysis
Motion analysis is used in computer vision, image processing, high-speed photography and machine vision that studies methods and applications in which two or more consecutive images from an image sequences, e.g., produced by a video camera or high-speed camera, are processed to produce information based on the apparent motion in the images. In some applications, the camera is fixed relative to the scene and objects are moving around in the scene, in some applications the scene is more or less fixed and the camera is moving, and in some cases both the camera and the scene are moving. The motion analysis processing can in the simplest case be to detect motion, i.e., find the points in the image where something is moving. More complex types of processing can be to track a specific object in the image over time, to group points that belong to the same rigid object that is moving in the scene, or to determine the magnitude and direction of the motion of every point in the image. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osteogenesis Imperfecta
Osteogenesis imperfecta (; OI), colloquially known as brittle bone disease, is a group of genetic disorders that all result in bones that break easily. The range of symptoms—on the skeleton as well as on the body's other organs—may be mild to severe. Symptoms found in various types of OI include whites of the eye (sclerae) that are blue instead, short stature, loose joints, hearing loss, breathing problems and problems with the teeth (dentinogenesis imperfecta). Potentially life-threatening complications, all of which become more common in more severe OI, include: tearing ( dissection) of the major arteries, such as the aorta; pulmonary valve insufficiency secondary to distortion of the ribcage; and basilar invagination. The underlying mechanism is usually a problem with connective tissue due to a lack of, or poorly formed, type I collagen. In more than 90% of cases, OI occurs due to mutations in the ''COL1A1'' or ''COL1A2'' genes. These mutations may be inherited ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peripheral Quantitative Computed Tomography
Quantitative computed tomography (QCT) is a medical technique that measures bone mineral density (BMD) using a standard X-ray Computed Tomography (CT) scanner with a calibration standard to convert Hounsfield Units (HU) of the CT image to bone mineral density values.J. E. Adams, "Quantitative computed tomography.," European journal of radiology, vol. 71, no. 3, pp. 415-24, Sep. 2009. Quantitative CT scans are primarily used to evaluate bone mineral density at the lumbar spine and hip. In general, solid phantoms placed in a pad under the patient during CT image acquisition are used for calibration. These phantoms contain materials that represent a number of different equivalent bone mineral densities. Usually either calcium hydroxyapatite (CaHAP) or potassium phosphate (K2HPO4) are used as the reference standard. History QCT was invented at University of California San Francisco (UCSF) during the 1970s. Douglas Boyd, PhD and Harry Genant, MD used a CT head scanner to do some of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mars500
The MARS-500 mission was a psychosocial isolation experiment conducted between 2007 and 2011 by Russia, the European Space Agency, and China, in preparation for an unspecified future crewed spaceflight to the planet Mars. The experiment's facility was located at the Russian Academy of Sciences' Institute of Biomedical Problems (IBMP) in Moscow, Russia. Between 2007 and 2011, three different crews of volunteers lived and worked in a mock-up spacecraft at IBMP. The final stage of the experiment, which was intended to simulate a 520-day crewed mission, was conducted by an all-male crew consisting of three Russians (Alexey Sitev, Sukhrob Kamolov, Alexander Smoleevskij), a Frenchman (Romain Charles), an Italian (Diego Urbina), and a Chinese citizen (Yue Wang). The mock-up facility simulated an Earth-Mars shuttle spacecraft, an ascent-descent craft, and the Martian surface. The volunteers who participated in the three stages included professionals with experience in engineering, m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Space Agency
, owners = , headquarters = Paris, Île-de-France, France , coordinates = , spaceport = Guiana Space Centre , seal = File:ESA emblem seal.png , seal_size = 130px , image = Views in the Main Control Room (12052189474).jpg , size = , caption = , acronym = , established = , employees = 2,200 , administrator = Director General Josef Aschbacher , budget = €7.2 billion (2022) , language = English and French (working languages) , website = , logo = European Space Agency logo.svg , logo_caption = Logo , image_caption = European Space Operations Centre (ESOC) Main Control Room The European Space Agency (ESA; french: Agence spatiale européenne , it, Agenzia Spaziale Europea, es, Agencia Espacial Europea ASE; german: Europäische Weltraumorganisation) is an intergovernmental organisation of 22 member states dedicated to the exploration of space. Established in 1975 and headquartered i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuromuscular
A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. It allows the motor neuron to transmit a signal to the muscle fiber, causing muscle contraction. Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. In the neuromuscular system nerves from the central nervous system and the peripheral nervous system are linked and work together with muscles. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-gated calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmins) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cerebral Palsy
Cerebral palsy (CP) is a group of movement disorders that appear in early childhood. Signs and symptoms vary among people and over time, but include poor coordination, stiff muscles, weak muscles, and tremors. There may be problems with sensation, vision, hearing, and speaking. Often, babies with cerebral palsy do not roll over, sit, crawl or walk as early as other children of their age. Other symptoms include seizures and problems with thinking or reasoning, which each occur in about one-third of people with CP. While symptoms may get more noticeable over the first few years of life, underlying problems do not worsen over time. Cerebral palsy is caused by abnormal development or damage to the parts of the brain that control movement, balance, and posture. Most often, the problems occur during pregnancy, but they may also occur during childbirth or shortly after birth. Often, the cause is unknown. Risk factors include preterm birth, being a twin, certain infections during pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obesity
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity has individual, socioeconomic, and environmental causes. Some known causes are diet, physical activity, automation, urbanization, genetic susceptibility, medications, mental disorders, economic policies, endocrine disorders, and exposure to endocrine-disrupting chemicals. While a majority of obese individuals at any given time are attempting to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centre Of Gravity
In physics, the center of mass of a distribution of mass in space (sometimes referred to as the balance point) is the unique point where the weighted relative position of the distributed mass sums to zero. This is the point to which a force may be applied to cause a linear acceleration without an angular acceleration. Calculations in mechanics are often simplified when formulated with respect to the center of mass. It is a hypothetical point where the entire mass of an object may be assumed to be concentrated to visualise its motion. In other words, the center of mass is the particle equivalent of a given object for application of Newton's laws of motion. In the case of a single rigid body, the center of mass is fixed in relation to the body, and if the body has uniform density, it will be located at the centroid. The center of mass may be located outside the physical body, as is sometimes the case for hollow or open-shaped objects, such as a horseshoe. In the case of a distri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prader–Willi Syndrome
Prader–Willi syndrome (PWS) is a genetic disorder caused by a loss of function of specific genes on chromosome 15. In newborns, symptoms include weak muscles, poor feeding, and slow development. Beginning in childhood, those affected become constantly hungry, which often leads to obesity and type 2 diabetes. Mild to moderate intellectual impairment and behavioral problems are also typical of the disorder. Often, affected individuals have a narrow forehead, small hands and feet, short height, and light skin and hair. Most are unable to have children. About 74% of cases occur when part of the father's chromosome 15 is deleted. In another 25% of cases, the affected person has two copies of the maternal chromosome 15 from the mother and lacks the paternal copy. As parts of the chromosome from the mother are turned off through imprinting, they end up with no working copies of certain genes. PWS is not generally inherited, but rather the genetic changes happen during the format ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pediatrics
Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the age of 18. The American Academy of Pediatrics recommends people seek pediatric care through the age of 21, but some pediatric subspecialists continue to care for adults up to 25. Worldwide age limits of pediatrics have been trending upward year after year. A medical doctor who specializes in this area is known as a pediatrician, or paediatrician. The word ''pediatrics'' and its cognates mean "healer of children," derived from the two Greek words: (''pais'' "child") and (''iatros'' "doctor, healer"). Pediatricians work in clinics, research centers, universities, general hospitals and children's hospitals, including those who practice pediatric subspecialties (e.g. neonatology requires resources available in a NICU). History The ear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
