Mark Pepys
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Mark Pepys
Sir Mark Brian Pepys (born 18 September 1944) is a South African-born British academic of medicine. He was until 2011 Professor of Medicine at University College London and Head of Medicine at the Hampstead Campus and the Royal Free Hospital. Education Pepys was born in Cape Town, South Africa, the son of physician Jack Pepys and Rhoda Gertrude Pepys (''née'' Kussel). He moved to the UK in 1948. He finished his early education at the University of Cambridge, and then qualified as a medical doctor at University College London Medical School. He then returned to Cambridge where he was awarded a PhD in Immunology in 1973. Awards and honours Pepys won the GlaxoSmithKline Prize in 2007 "for his excellent work as a clinical scientist who has identified specific proteins as new therapeutic targets and developed novel drugs with potential use in amyloidosis, Alzheimer's disease and cardiovascular disease". In 1998, Pepys was elected a Fellow of the Royal Society (FRS). His nominati ...
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Cape Town
Cape Town ( af, Kaapstad; , xh, iKapa) is one of South Africa's three capital cities, serving as the seat of the Parliament of South Africa. It is the legislative capital of the country, the oldest city in the country, and the second largest (after Johannesburg). Colloquially named the ''Mother City'', it is the largest city of the Western Cape province, and is managed by the City of Cape Town metropolitan municipality. The other two capitals are Pretoria, the executive capital, located in Gauteng, where the Presidency is based, and Bloemfontein, the judicial capital in the Free State, where the Supreme Court of Appeal is located. Cape Town is ranked as a Beta world city by the Globalization and World Cities Research Network. The city is known for its harbour, for its natural setting in the Cape Floristic Region, and for landmarks such as Table Mountain and Cape Point. Cape Town is home to 66% of the Western Cape's population. In 2014, Cape Town was named the best place ...
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Transthyretin
Transthyretin (TTR or TBPA) is a transport protein in the plasma and cerebrospinal fluid that transports the thyroid hormone thyroxine (T4) and retinol to the liver. This is how transthyretin gained its name: ''transports thyroxine and retinol''. The liver secretes TTR into the blood, and the choroid plexus secretes TTR into the cerebrospinal fluid. TTR was originally called prealbumin (or thyroxine-binding prealbumin) because it migrated faster than albumin on electrophoresis gels. Prealbumin was felt to be a misleading name, it is not a synthetic precursor of albumin. The alternative name TTR was proposed by DeWitt Goodman in 1981. Transthyretin protein is encoded by the ''TTR'' gene located on the 18th chromosome. Binding affinities It functions in concert with two other thyroid hormone-binding proteins in the serum: In cerebrospinal fluid TTR is the primary carrier of T4. TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding pr ...
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Fellows Of The Royal College Of Physicians Of Edinburgh
The Royal College of Physicians of Edinburgh (RCPE) is a medical royal college in Scotland. It is one of three organisations that sets the specialty training standards for physicians in the United Kingdom. It was established by Royal charter in 1681. The college claims to have 12,000 fellows and members worldwide. History The RCPE was formed by a royal charter, granted in 1681, with Sir Robert Sibbald recognised as playing a key part in the negotiations. Three applications preceded this and had been unsuccessful. There were 21 original Fellows, eleven of whom were graduates or students of the University of Leiden. The Universities (Scotland) Act 1858 resulted in several items from the College's Charter becoming obsolete, and they obtained a further charter on 31 October 1861. In 1920 the College enacted changes that allowed women to be admitted on the same terms as men. The charter was amended on 7 May 2005. Edinburgh Pharmacopoeia In 1699 The College first published a ...
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Knights Bachelor
The title of Knight Bachelor is the basic rank granted to a man who has been knighted by the monarch but not inducted as a member of one of the organised orders of chivalry; it is a part of the British honours system. Knights Bachelor are the most ancient sort of British knight (the rank existed during the 13th-century reign of King Henry III), but Knights Bachelor rank below knights of chivalric orders. A man who is knighted is formally addressed as "Sir irst Name urname or "Sir irst Name and his wife as "Lady urname. Criteria Knighthood is usually conferred for public service; amongst its recipients are all male judges of His Majesty's High Court of Justice in England. It is possible to be a Knight Bachelor and a junior member of an order of chivalry without being a knight of that order; this situation has become rather common, especially among those recognized for achievements in entertainment. For instance, Sir Michael Gambon, Sir Derek Jacobi, Sir Anthony Hopkins, Sir ...
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Fellows Of Trinity College, Cambridge
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places * Fellows, California, USA * Fellows, Wisconsin, ghost town, USA Other uses * Fellows Auctioneers, established in 1876. *Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton * Fellows (surname) See also *North Fellows Historic District, listed on the National Register of Historic Places in Wapello County, Iowa *Justice Fellows (other) Justice Fellows may refer to: * Grant Fellows (1865–1929), associate justice of the Michigan Supreme Court * Raymond Fellows (1885–1957), associate justice of the Maine Supreme Judicial Court {{disambiguation, tndis ...
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Fellows Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural knowledge, including mathematics, engineering science, and medical science". Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki Ramakrishnan ...
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South African Scientists
South is one of the cardinal directions or Points of the compass, compass points. The direction is the opposite of north and is perpendicular to both east and west. Etymology The word ''south'' comes from Old English ''sūþ'', from earlier Proto-Germanic language, Proto-Germanic ''*sunþaz'' ("south"), possibly related to the same Proto-Indo-European language, Proto-Indo-European root that the word ''sun'' derived from. Some languages describe south in the same way, from the fact that it is the direction of the sun at noon (in the Northern Hemisphere), like Latin meridies 'noon, south' (from medius 'middle' + dies 'day', cf English meridional), while others describe south as the right-hand side of the rising sun, like Biblical Hebrew תֵּימָן teiman 'south' from יָמִין yamin 'right', Aramaic תַּימנַא taymna from יָמִין yamin 'right' and Syriac ܬܰܝܡܢܳܐ taymna from ܝܰܡܝܺܢܳܐ yamina (hence the name of Yemen, the land to the south/right of the ...
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People From Cape Town
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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1944 Births
Events Below, the events of World War II have the "WWII" prefix. January * January 2 – WWII: ** Free France, Free French General Jean de Lattre de Tassigny is appointed to command First Army (France), French Army B, part of the Sixth United States Army Group in North Africa. ** Landing at Saidor: 13,000 US and Australian troops land on Papua New Guinea, in an attempt to cut off a Japanese retreat. * January 8 – WWII: Philippine Commonwealth troops enter the province of Ilocos Sur in northern Luzon and attack Japanese forces. * January 11 ** President of the United States Franklin D. Roosevelt proposes a Second Bill of Rights for social and economic security, in his State of the Union address. ** The Nazi German administration expands Kraków-Płaszów concentration camp into the larger standalone ''Konzentrationslager Plaszow bei Krakau'' in occupied Poland. * January 12 – WWII: Winston Churchill and Charles de Gaulle begin a 2-day conference in Marrakech ...
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SAP Scan
A SAP scan is a type of nuclear medicine imaging test which uses iodine-123 (123I) and serum amyloid P component (SAP) to diagnose amyloidosis. In patients with amyloidosis, large deposits of SAP coat the affected organs, in addition to the low levels normally found in the blood stream. The injected 123I-SAP localises specifically to amyloid deposits, showing up as hot spots in the image. Procedure The radiopharmaceutical is injected into the patient, with imaging taking place on a gamma camera 6-24 hours later. An early blood-pool image provides a baseline for comparison with the organ SAP uptake after 24 hours. Availability Europe 123I-SAP was granted orphan designation by the European Medicines Agency in 2003, however this was withdrawn in 2016. SAP scanning is only carried out at two European centres; in the United Kingdom from the National Amyloidosis Centre, based at the Royal Free Hospital, and in the Netherlands at University Medical Center Groningen. North America SAP ...
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2012 New Year Honours
1 (one, unit, unity) is a number representing a single or the only entity. 1 is also a numerical digit and represents a single unit of counting or measurement. For example, a line segment of ''unit length'' is a line segment of length 1. In conventions of sign where zero is considered neither positive nor negative, 1 is the first and smallest positive integer. It is also sometimes considered the first of the infinite sequence of natural numbers, followed by  2, although by other definitions 1 is the second natural number, following  0. The fundamental mathematical property of 1 is to be a multiplicative identity, meaning that any number multiplied by 1 equals the same number. Most if not all properties of 1 can be deduced from this. In advanced mathematics, a multiplicative identity is often denoted 1, even if it is not a number. 1 is by convention not considered a prime number; this was not universally accepted until the mid-20th century. Additionally, 1 is the ...
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