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Marcelle Lapicque
Marcelle de Heredia Lapicque (1873 – 1960) was a French neurophysiologist known for her research on nerve impulses (chronaxie) and the effects of poisons, especially strychnine, on chronaxie. She was in charge of the Laboratoire des Hautes-Études General Physiology laboratory until her death. Marcelle Lapicque, though overshadowed in histories of science by her husband, Louis Lapicque, was an influential scientist in her own right, publishing many papers as sole author and holding a membership to the Société de Biologie. Louis Lapicque "insisted on the importance of his wife as equal co-worker in all his research".. She was the daughter of French politician Severiano de Heredia Severiano de Heredia (8 November 1836 – 9 February 1901) was a Cuban-born biracial politician, a freemason, a left-wing republican, naturalized as French in 1870, who was president of the municipal council of Paris from 1 August 1879 to 12 Febru .... References French neuroscientists Fre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurophysiology
Neurophysiology is a branch of physiology and neuroscience that studies nervous system function rather than nervous system architecture. This area aids in the diagnosis and monitoring of neurological diseases. Historically, it has been dominated by electrophysiology—the electrical recording of neural activity ranging from the molar (the electroencephalogram, EEG) to the cellular (intracellular recording of the properties of single neurons), such as patch clamp, voltage clamp, extracellular single-unit recording and recording of local field potentials. However, since the neurone is an electrochemical machine, it is difficult to isolate electrical events from the metabolic and molecular processes that cause them. Thus, neurophysiologists currently utilise tools from chemistry (calcium imaging), physics (functional magnetic resonance imaging, Functional magnetic resonance imaging, fMRI), and molecular biology (site directed mutations) to examine brain activity. The word originates f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nerve Impulses
An action potential occurs when the membrane potential of a specific cell location rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and in some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells. In neurons, action potentials play a central role in cell-cell communication by providing for—or with regard to saltatory conduction, assisting—the propagation of signals along the neuron's axon toward synaptic boutons situated at the ends of an axon; these signals can then connect with other neurons at synapses, or to motor cells or glands. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events lea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chronaxie
Chronaxie is the minimum time required for an electric current double the strength of the rheobase to stimulate a muscle or a neuron. Rheobase is the lowest intensity with indefinite pulse duration which just stimulated muscles or nerves. Chronaxie is dependent on the density of voltage-gated sodium channels in the cell, which affect that cell’s excitability. Chronaxie varies across different types of tissue: fast-twitch muscles have a lower chronaxie, slow-twitch muscles have a higher one. Chronaxie is the tissue-excitability parameter that permits choice of the optimum stimulus pulse duration for stimulation of any excitable tissue. Chronaxie (c) is the Lapicque descriptor of the stimulus pulse duration for a current of twice rheobasic (b) strength, which is the threshold current for an infinitely long-duration stimulus pulse. Lapicque showed that these two quantities (c,b) define the strength-duration curve for current: I = b(1+c/d), where d is the pulse duration. However, the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strychnine
Strychnine (, , US chiefly ) is a highly toxic, colorless, bitter, crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine, when inhaled, swallowed, or absorbed through the eyes or mouth, causes poisoning which results in muscular convulsions and eventually death through asphyxia. While it is no longer used medicinally, it was used historically in small doses to strengthen muscle contractions, such as a heart and bowel stimulant and performance-enhancing drug. The most common source is from the seeds of the ''Strychnos nux-vomica'' tree. Biosynthesis Strychnine is a terpene indole alkaloid belonging to the ''Strychnos'' family of '' Corynanthe'' alkaloids, and it is derived from tryptamine and secologanin. The biosynthesis of strychine was solved in 2022. The enzyme, strictosidine synthase, catalyzes the condensation of tryptamine and secologanin, followed by a Pictet-Spengler reaction to form strictosidine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louis Lapicque
Louis Édouard Lapicque (1 August 1866 – 6 December 1952) was a French neuroscientist, socialist activist, antiboulangist, dreyfusard and freemason who was very influential in the early 20th century. One of his main contributions was to propose the integrate-and-fire model of the neuron in a seminal article published in 1907. Today, this model of the neuron is still one of the most popular models in computational neuroscience for both cellular and neural networks studies, as well as in mathematical neuroscience because of its simplicity. A review article was published for the centenary of the original Lapicque's 1907 paper - this review also contains an English translation of the original paper. His wife, Marcelle Lapicque Marcelle de Heredia Lapicque (1873 – 1960) was a French Neurophysiology, neurophysiologist known for her research on nerve impulses (chronaxie) and the effects of poisons, especially strychnine, on chronaxie. She was in charge of the Laboratoire ..., w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Société De Biologie
The Société de biologie is a learned society founded in Paris in 1848. The society was conceived during the French Revolution of 1848. The members of the society held regular meetings and published the proceedings in a new scientific journal. The founding members of the society included Claude Bernard, the naturalist Charles-Philippe Robin, and the surgeon Eugène Follin. Its first president was the doctor and dermatologist Pierre Rayer. Bernard was unanimously elected president of the society in 1867 upon Rayer's death. Historian Mirko Grmek said the society brought together the best physiologists and naturalists in Paris, and that Bernard regularly attended the weekly meetings. During 1849 he spoke at nearly all the sessions. Of the 227 scientific articles published by Bernard from 1848 onwards, 79 of them were published in the ''Comptes-rendus et Mémoires de la Société de Biologie''. Marcellin Berthelot Pierre Eugène Marcellin Berthelot (; 25 October 1827 – 18 Ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Severiano De Heredia
Severiano de Heredia (8 November 1836 – 9 February 1901) was a Cuban-born biracial politician, a freemason, a left-wing republican, naturalized as French in 1870, who was president of the municipal council of Paris from 1 August 1879 to 12 February 1880, making him the only native of the American continent who was appointed on relevant post of the Mayor of Paris and the first mayor of African descent of a Western world capital. In 1880, he succeeded Victor Hugo in the presidency of the Philotechnical Association. He served in the Chamber of Deputies from 1881 to 1889 and was briefly Minister of Public Works for the cabinet of Maurice Rouvier in 1887, at the time when the Eiffel Tower first started being built, where he planned and oversaw the construction of some of the finest French highways. He is believed to be a cousin of the famous French poet José-Maria de Heredia. Biography Personal life Severiano de Heredia was born in Matanzas, Cuba, to Henri de Heredia and mulatta B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Neuroscientists
French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ** French cuisine, cooking traditions and practices Fortnite French places Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), 2008 * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a particular type of military jacket or tunic used in the Russian Empire and Soviet Union * French's, an American brand of mustard condiment * French catheter scale, a unit of measurement of diameter * French Defence, a chess opening * French kiss, a type of kiss involving the tongue See also * France (other) * Franch, a surname * French ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Women Scientists
French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ** French cuisine, cooking traditions and practices Fortnite French places Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), 2008 * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a particular type of military jacket or tunic used in the Russian Empire and Soviet Union * French's, an American brand of mustard condiment * French catheter scale, a unit of measurement of diameter * French Defence, a chess opening * French kiss, a type of kiss involving the tongue See also * France (other) * Franch, a surname * Fre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Women Neuroscientists
French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ** French cuisine, cooking traditions and practices Fortnite French places Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), 2008 * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a particular type of military jacket or tunic used in the Russian Empire and Soviet Union * French's, an American brand of mustard condiment * French catheter scale, a unit of measurement of diameter * French Defence, a chess opening * French kiss, a type of kiss involving the tongue See also * France (other) * Franch, a surname * French ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French People Of Dominican Republic Descent
French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ** French cuisine, cooking traditions and practices Fortnite French places Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), 2008 * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a particular type of military jacket or tunic used in the Russian Empire and Soviet Union * French's, an American brand of mustard condiment * French catheter scale, a unit of measurement of diameter * French Defence, a chess opening * French kiss, a type of kiss involving the tongue See also * France (other) * Franch, a surname * French ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
