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Myerson's Sign
Myerson's sign or glabellar tap sign is a clinical physical examination finding in which a patient is unable to resist blinking when tapped repetitively on the glabella, the area above the nose and between the eyebrows. It is often referred to as the glabellar reflex. It is often an early symptom of Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ..., but can also be seen in early dementia as well as other progressive neurologic illness. It is named for Abraham Myerson, an American neurologist. References Symptoms and signs: Nervous system {{med-sign-stub ...
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Physical Examination
In a physical examination, medical examination, or clinical examination, a medical practitioner examines a patient for any possible medical signs or symptoms of a medical condition. It generally consists of a series of questions about the patient's medical history followed by an examination based on the reported symptoms. Together, the medical history and the physical examination help to determine a diagnosis and devise the treatment plan. These data then become part of the medical record. Types Routine The ''routine physical'', also known as ''general medical examination'', ''periodic health evaluation'', ''annual physical'', ''comprehensive medical exam'', ''general health check'', ''preventive health examination'', ''medical check-up'', or simply ''medical'', is a physical examination performed on an asymptomatic patient for medical screening purposes. These are normally performed by a pediatrician, family practice physician, physician assistant, a certified nurse pr ...
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Blinking
Blinking is a bodily function; it is a semi-autonomic rapid closing of the eyelid. A single blink is determined by the forceful closing of the eyelid or inactivation of the levator palpebrae superioris and the activation of the palpebral portion of the orbicularis oculi, not the full open and close. It is an essential function of the eye that helps spread tears across and remove irritants from the surface of the cornea and conjunctiva. Blinking may have other functions since it occurs more often than necessary just to keep the eye lubricated. Researchers think blinking may help with disengagement of attention; following blink onset, cortical activity decreases in the dorsal network and increases in the default-mode network, associated with internal processing. Blink speed can be affected by elements such as fatigue, eye injury, medication, and disease. The blinking rate is determined by the "blinking center", but it can also be affected by external stimulus. Some animals, such ...
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Glabella
The glabella, in humans, is the area of skin between the eyebrows and above the nose. The term also refers to the underlying bone that is slightly depressed, and joins the two brow ridges. It is a cephalometric landmark that is just superior to the nasion. Etymology The term for the area is derived from the Latin , meaning 'smooth, hairless'. In medical science The skin of the glabella may be used to measure skin turgor in suspected cases of dehydration by gently pinching and lifting it. When released, the glabella of a dehydrated patient tends to remain extended ("tented"), rather than returning to its normal shape. See also * Glabellar reflex The glabellar reflex, also known as the "glabellar tap sign", is a primitive reflex elicited by repetitive tapping of the the smooth part of the forehead above the nose and between the eyebrows. Subjects respond to the first several taps by blink ... References Bones of the head and neck {{musculoskeletal-stub ...
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Eyebrows
An eyebrow is an area of short hairs above each eye that follows the shape of the lower margin of the brow ridges of some mammals. In humans, eyebrows serve two main functions: first, communication through facial expression, and second, prevention of sweat, water, and other debris from falling down into the eye socket. It is common for people to modify their eyebrows by means of hair removal and makeup. Functions A number of theories have been proposed to explain the function of the eyebrow in humans. One approach suggests its main function is to prevent moisture (mostly sweat and rain) from flowing into the eye. Another theory holds that clearly visible eyebrows provided safety from predators when early hominid groups started sleeping on the ground. Recent research, however, suggests eyebrows in humans developed as a means of communication and that this is their primary function. Humans developed a smooth forehead with visible, hairy eyebrows capable of a wide range of movemen ...
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Glabellar Reflex
The glabellar reflex, also known as the "glabellar tap sign", is a primitive reflex elicited by repetitive tapping of the the smooth part of the forehead above the nose and between the eyebrows. Subjects respond to the first several taps by blinking; if tapping were to then be made to persist, in cognitively intact individuals this would lead to habituation and consequent suppression of blinking. If instead the blinking were to persist along with the tapping, this is known as Myerson's sign, and is abnormal and a sign of frontal release; it is often seen in people who have Parkinson's disease. The afferent sensory signals are transmitted by the trigeminal nerve to the brain stem; the efferent signals go to the orbicularis oculi muscle via the facial nerve, causing the muscle to reflexively contract, yielding blinking. This reflex was first identified by Walker Overend. See also * Glabella The glabella, in humans, is the area of skin between the eyebrows and above the nose. ...
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Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms become more common. The most obvious early symptoms are tremor, rigidity, slowness of movement, and difficulty with walking. Cognitive and behavioral problems may also occur with depression, anxiety, and apathy occurring in many people with PD. Parkinson's disease dementia becomes common in the advanced stages of the disease. Those with Parkinson's can also have problems with their sleep and sensory systems. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain, leading to a dopamine deficit. The cause of this cell death is poorly understood, but involves the build-up of misfolded proteins into Lewy bodies in the neurons. Collectively, the main motor symptoms are also known as ...
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Abraham Myerson
Abraham Myerson (1881–1948) was a Lithuanian neurologist, psychiatrist, clinician, pathologist, and researcher. He had a special interest in the heredity of psychiatric and neurologic disease. Early life and education Myerson was born in Lithuania, the son of a Jewish school teacher. His father emigrated to the United States in 1885, and sent for his family in 1886, settling in New Britain, Connecticut. In 1892, the family moved to Boston, Massachusetts. He attended the Boston public schools, graduated from high school in 1898, and then worked for seven years to earn money to attend medical school. He attended the College of Physicians and Surgeons of Columbia University for one year and then left for financial reasons. He worked as a street car conductor for a year, and then returned to Columbia for his second year. He transferred to Tufts Medical School in Boston, and graduated in 1908 with a M.D. At Tufts, Myerson was a student of Dr. Morton Prince, and in his later years, My ...
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