Morgagni Stewart Morel Syndrome
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Morgagni Stewart Morel Syndrome
Morgagni-Stewart-Morel syndrome is a condition with a wide range of associated endocrine problems including: diabetes mellitus, diabetes insipidus, and hyperparathyroidism. Other signs and symptoms include headaches, vertigo, hirsutism, menstrual disorder, galactorrhoea, obesity, depression, and seizures. Thickening of the inner table of the frontal part of the skull a usually benign condition known as hyperostosis frontalis interna. The syndrome was first described in 1765. It is named after the Italian anatomist and pathologist Giovanni Battista Morgagni, the British neurologist Roy Mackenzie Stewart, and the Swiss psychiatrist Ferdinand Morel. Cause Diagnosis The diagnosis of Morgagni-Stewart-Morel is based upon a radiological finding of hyperostosis frontalis interna Hyperostosis frontalis interna is a common, benign thickening of the inner side of the frontal bone of the skull. It is found predominantly in women after menopause and is usually asymptomatic. Mostly f ...
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Endocrine
The endocrine system is a messenger system comprising feedback loops of the hormones released by internal glands of an organism directly into the circulatory system, regulating distant target organs. In vertebrates, the hypothalamus is the neural control center for all endocrine systems. In humans, the major endocrine glands are the thyroid gland and the adrenal glands. The study of the endocrine system and its disorders is known as endocrinology. Glands that signal each other in sequence are often referred to as an axis, such as the hypothalamic-pituitary-adrenal axis. In addition to the specialized endocrine organs mentioned above, many other organs that are part of other body systems have secondary endocrine functions, including bone, kidneys, liver, heart and gonads. For example, the kidney secretes the endocrine hormone erythropoietin. Hormones can be amino acid complexes, steroids, eicosanoids, leukotrienes, or prostaglandins. The endocrine system can be contrasted ...
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Depression (mood)
Depression is a mental state of low mood and aversion to activity, which affects more than 280 million people of all ages (about 3.5% of the global population). Classified medically as a mental and behavioral disorder, the experience of depression affects a person's thoughts, behavior, motivation, feelings, and sense of well-being. The core symptom of depression is said to be anhedonia, which refers to loss of interest or a loss of feeling of pleasure in certain activities that usually bring joy to people. Depressed mood is a symptom of some mood disorders such as major depressive disorder and dysthymia; it is a normal temporary reaction to life events, such as the loss of a loved one; and it is also a symptom of some physical diseases and a side effect of some drugs and medical treatments. It may feature sadness, difficulty in thinking and concentration and a significant increase or decrease in appetite and time spent sleeping. People experiencing depression may have ...
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Virilism
Virilization or masculinization is the biological development of adult male characteristics in young males or females. Most of the changes of virilization are produced by androgens. Virilization is most commonly used in three medical and biology of sex contexts: prenatal biological sexual differentiation, the postnatal changes of typical chromosomal male (46, XY) puberty, and excessive androgen effects in typical chromosomal females (46, XX). It is also the intended result of androgen replacement therapy in males with delayed puberty and low testosterone. Prenatal virilization In the prenatal period, virilization refers to closure of the perineum, thinning and wrinkling (rugation) of the scrotum, growth of the penis, and closure of the urethral groove to the tip of the penis. In this context, ''masculinization'' is synonymous with ''virilization.'' Prenatal virilization of genetic females and undervirilization of genetic males are common causes of ambiguous genitalia and inters ...
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Ferdinand Morel
Ferdinand is a Germanic name composed of the elements "protection", "peace" (PIE "to love, to make peace") or alternatively "journey, travel", Proto-Germanic , abstract noun from root "to fare, travel" (PIE , "to lead, pass over"), and "courage" or "ready, prepared" related to Old High German "to risk, venture." The name was adopted in Romance languages from its use in the Visigothic Kingdom. It is reconstructed as either Gothic or . It became popular in German-speaking Europe only from the 16th century, with Habsburg rule over Spain. Variants of the name include , , , and in Spanish, in Catalan, and and in Portuguese. The French forms are , '' Fernand'', and , and it is '' Ferdinando'' and in Italian. In Hungarian both and are used equally. The Dutch forms are and ''Ferry''. There are numerous short forms in many languages, such as the Finnish . There is a feminine Spanish, Portuguese and Italian form, . Royalty Aragón/León/Castile/Spain *Ferdina ...
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Roy Mackenzie Stewart
Roy Mackenzie Stewart (1889–1964) was a Scottish neurologist. After education at Lord Williams's Grammar School at Thame, Oxfordshire, Roy Mackenzie Stewart entered the University of Edinburgh Medical School and graduated there MB ChB (Edin.) in 1911. After serving on the staff of the Lancashire County Asylum at Prestwich, he joined in May 1915 the RAMC and was sent to France, where the explosion of a heavy gun caused him to have tinnitus for the remainder of his life. He was then stationed as a neurologist at Moss Side Military Hospital at Maghull (near Liverpool), from 1917 in 1918 in Salonica, and from May to November 1919 at the Royal Victoria Hospital, Netley. He received in 1920 the M.D. degree from the University of Edinburgh Medical School. In 1920 he became deputy medical superintendent of Whittingham Mental Hospital Whittingham Hospital was a psychiatric hospital in the parish of Whittingham, near Preston, Lancashire, England. The hospital opened in 1873 as th ...
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Giovanni Battista Morgagni
Giovanni Battista Morgagni (25 February 1682 – 6 December 1771) was an Italian anatomist, generally regarded as the father of modern anatomical pathology, who taught thousands of medical students from many countries during his 56 years as Professor of Anatomy at the University of Padua. His most significant literary contribution, the monumental five-volume ''On the Seats and Causes of Disease'', embodied a lifetime of experience in anatomical dissection and observation, and established the fundamental principle that most diseases are not vaguely dispersed throughout the body, but originate locally, in specific organs and tissues. Education His parents were in comfortable circumstances, but not of the nobility; it appears from his letters to Giovanni Maria Lancisi that Morgagni had ambitions to improve his rank. It may be inferred that he succeeded from the fact that he is described on a memorial tablet at Padua as ''nobilis forolensis'', "noble of Forlì", apparently by right ...
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Hyperostosis Frontalis Interna
Hyperostosis frontalis interna is a common, benign thickening of the inner side of the frontal bone of the skull. It is found predominantly in women after menopause and is usually asymptomatic. Mostly frequently it is found as an incidental finding discovered during an X-ray An X-ray, or, much less commonly, X-radiation, is a penetrating form of high-energy electromagnetic radiation. Most X-rays have a wavelength ranging from 10  picometers to 10  nanometers, corresponding to frequencies in the range 30&nb ... or CT scan of the skull. Additional images References * External links Skull Osteopathies {{musculoskeletal-disease-stub ...
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Seizures
An epileptic seizure, informally known as a seizure, is a period of symptoms due to abnormally excessive or neural oscillation, synchronous neuronal activity in the brain. Outward effects vary from uncontrolled shaking movements involving much of the body with loss of consciousness (tonic-clonic seizure), to shaking movements involving only part of the body with variable levels of consciousness (focal seizure), to a subtle momentary loss of awareness (absence seizure). Most of the time these episodes last less than two minutes and it takes some time to return to normal. Urinary incontinence, Loss of bladder control may occur. Seizures may be provoked and unprovoked. Provoked seizures are due to a temporary event such as low blood sugar, alcohol withdrawal, abusing alcohol together with prescription medication, low blood sodium, fever, brain infection, or concussion. Unprovoked seizures occur without a known or fixable cause such that ongoing seizures are likely. Unprovoked seizur ...
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Obesity
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity has individual, socioeconomic, and environmental causes. Some known causes are diet, physical activity, automation, urbanization, genetic susceptibility, medications, mental disorders, economic policies, endocrine disorders, and exposure to endocrine-disrupting chemicals. While a majority of obese individuals at any given time are attempting to ...
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Diabetes Mellitus
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to lo ...
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Galactorrhoea
Galactorrhea ( also spelled galactorrhoea) ( galacto- + -rrhea) or lactorrhea ( lacto- + -rrhea) is the spontaneous flow of milk from the breast, unassociated with childbirth or nursing. Galactorrhea is reported to occur in 5–32% of women. Much of the difference in reported incidence can be attributed to different definitions of galactorrhea. Although frequently benign, it may be caused by serious underlying conditions and should be properly investigated. Galactorrhea also occurs in males, newborn infants and adolescents of both sexes. Causes Galactorrhea can take place as a result of dysregulation of certain hormones. Hormonal causes most frequently associated with galactorrhea are hyperprolactinemia and thyroid conditions with elevated levels of thyroid-stimulating hormone (TSH) or thyrotropin-releasing hormone (TRH). No obvious cause is found in about 50% of cases. Lactation requires the presence of prolactin, and the evaluation of galactorrhea includes eliciting a histor ...
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Menstrual Disorder
A menstrual disorder is characterized as any abnormal condition with regards to a person's menstrual cycle. There are many different types of menstrual disorders that vary with signs and symptoms, including pain during menstruation, heavy bleeding, or absence of menstruation. Normal variations can occur in menstrual patterns but generally menstrual disorders can also include periods that come sooner than 21 days apart, more than 3 months apart, or last more than 10 days in duration. Variations of the menstrual cycle are mainly caused by the immaturity of the hypothalamic-pituitary-ovarian (HPO) axis, and early detection and management is required in order to minimize the possibility of complications regarding future reproductive ability. Though menstrual disorders were once considered more of a nuisance problem, they are now widely recognized as having a serious impact on society in the form of days lost from work brought about by the pain and suffering experienced by women. These ...
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