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Mitral Valve Repair
Mitral valve repair is a cardiac surgery procedure performed by cardiac surgeons to treat stenosis (narrowing) or regurgitation (leakage) of the mitral valve. The mitral valve is the "inflow valve" for the left side of the heart. Blood flows from the lungs, where it picks up oxygen, through the pulmonary veins, to the left atrium of the heart. After the left atrium fills with blood, the mitral valve allows blood to flow from the left atrium into the heart's main pumping chamber called the left ventricle. It then closes to keep blood from leaking back into the left atrium or lungs when the ventricle contracts (squeezes) to push blood out to the body. It has two flaps, or leaflets, known as cusps. The techniques of mitral valve repair include inserting a cloth-covered ring around the valve to bring the leaflets into contact with each other ( annuloplasty), removal of redundant/loose segments of the leaflets (quadrangular resection), and re-suspension of the leaflets with artificia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiac Surgery
Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease (for example, with coronary artery bypass grafting); to correct congenital heart disease; or to treat valvular heart disease from various causes, including endocarditis, Rheumatic fever, rheumatic heart disease, and atherosclerosis. It also includes heart transplantation. History 19th century The earliest operations on the pericardium (the sac that surrounds the heart) took place in the 19th century and were performed by Francisco Romero (surgeon), Francisco Romero (1801) in the city of Almería (Spain), Dominique Jean Larrey (1810), Henry Dalton (1891), and Daniel Hale Williams (1893). The first surgery on the heart itself was performed by Axel Cappelen on 4 September 1895 at Rikshospitalet in Kristiania, now Oslo. Cappelen ligature (medicine), ligated a bleeding coronary circulation, coronary ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Degeneration (medical)
Degeneration is deterioration in the medical sense. Generally, it is the change from a higher to a lower form. More specifically, it is the change of tissue to a lower or less functionally active form. *True degeneration: when there is actual chemical change of the tissue itself. *Infiltration: when the change consists of the deposit of abnormal matter in the tissues *Degenerative disease See also *macular degeneration *neurodegenerative disease A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic ... References Dorland's Illustrated Medical Dictionary (Twenty-sixth Edition) () Medical terminology {{med-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Median Sternotomy
Median sternotomy is a type of surgical procedure in which a vertical inline incision is made along the sternum, after which the sternum itself is divided using a sternal saw. This procedure provides access to the heart and lungs for surgical procedures such as heart transplant, lung transplant, corrective surgery for congenital heart defects, or coronary artery bypass surgery Coronary artery bypass surgery, also known as coronary artery bypass graft (CABG, pronounced "cabbage") is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve chest pai .... References {{Cardiac surgery Thoracic surgical procedures Surgical incisions ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alain F
Alain may refer to: People * Alain (given name), common given name, including list of persons and fictional characters with the name * Alain (surname) * "Alain", a pseudonym for cartoonist Daniel Brustlein * Alain, a standard author abbreviation used to indicate Henri Alain Liogier, also known as Brother Alain, as the author when citing a botanical name * Émile Chartier (1868–1951), French philosopher and antimilitarist commonly known as Alain Places * Alain, Iran, a village in Tehran Province, Iran * Al Ain, a city in Abu Dhabi, United Arab Emirates ** Al Ain International Airport in the United Arab Emirates * Val-Alain, Quebec, village of 950 people in Quebec, Canada Other uses * 1969 Alain (1935 CG), a Main-belt Asteroid discovered in 1935 * ''Alain'' (crab), a genus of crabs in the family Pinnotheridae * Prix Alain-Grandbois or Alain Grandbois Prize is awarded each year to an author for a book of poetry * Rosa 'Alain', popular red floribunda rose variety See also * Allain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Normalized Ratio
The prothrombin time (PT) – along with its derived measures of prothrombin ratio (PR) and international normalized ratio (INR) – is an assay for evaluating the ''extrinsic'' pathway and common pathway of coagulation. This blood test is also called ''protime INR'' and ''PT/INR''. They are used to determine the clotting tendency of blood, in such things as the measure of warfarin dosage, liver damage, and vitamin K status. PT measures the following coagulation factors: I (fibrinogen), II (prothrombin), V (proaccelerin), VII (proconvertin), and X (Stuart–Prower factor). PT is often used in conjunction with the activated partial thromboplastin time (aPTT) which measures the ''intrinsic'' pathway and common pathway of coagulation. Laboratory measurement The reference range for prothrombin time depends on the analytical method used, but is usually around 12–13 seconds (results should always be interpreted using the reference range from the laboratory that performed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anti-coagulant
Anticoagulants, commonly known as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time. Some of them occur naturally in blood-eating animals such as leeches and mosquitoes, where they help keep the bite area unclotted long enough for the animal to obtain some blood. As a class of medications, anticoagulants are used in therapy for thrombotic disorders. Oral anticoagulants (OACs) are taken by many people in pill or tablet form, and various intravenous anticoagulant dosage forms are used in hospitals. Some anticoagulants are used in medical equipment, such as sample tubes, blood transfusion bags, heart–lung machines, and dialysis equipment. One of the first anticoagulants, warfarin, was initially approved as a rodenticide. Anticoagulants are closely related to antiplatelet drugs and thrombolytic drugs by manipulating the various pathways of blood coagulation. Specifically, antiplatelet drugs inhibit platelet aggreg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artificial Heart Valve
An artificial heart valve is a one-way valve implanted into a person's heart to replace a heart valve that is not functioning properly (valvular heart disease). Artificial heart valves can be separated into three broad classes: mechanical heart valves, bioprosthetic tissue valves and engineered tissue valves. The human heart contains four valves: tricuspid valve, pulmonary valve, mitral valve and aortic valve. Their main purpose is to keep blood flowing in the proper direction through the heart, and from the heart into the major blood vessels connected to it (the pulmonary artery and the aorta). Heart valves can malfunction for a variety of reasons, which can impede the flow of blood through the valve ( stenosis) and/or let blood flow backwards through the valve ( regurgitation). Both processes put strain on the heart and may lead to serious problems, including heart failure. While some dysfunctional valves can be treated with drugs or repaired, others need to be replaced wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mitral Valve Replacement
Mitral valve replacement is a procedure whereby the diseased mitral valve of a patient's heart is replaced by either a mechanical or tissue (bioprosthetic) valve. The mitral valve may need to be replaced because: * The valve is leaky (mitral valve regurgitation) * The valve is narrowed and doesn't open properly (mitral valve stenosis) Causes of mitral valve disease include infection, calcification and inherited collagen disease. Current mitral valve replacement approaches include open heart surgery and minimally invasive cardiac surgery (MICS). Normal mitral valve anatomy and physiology The mitral valve is a bileaflet valve sited between the left atrium and left ventricle, responsible for preventing blood flowing from the ventricle to the atrium when the heart contracts. It is elliptical, and its area varies from 5.0 to 11.4 cm2. The valve leaflets are separated by two commissures, and each leaflet of the valve (anterior leaflet, the large one, and posterior leaflet, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artificial Heart Valve
An artificial heart valve is a one-way valve implanted into a person's heart to replace a heart valve that is not functioning properly (valvular heart disease). Artificial heart valves can be separated into three broad classes: mechanical heart valves, bioprosthetic tissue valves and engineered tissue valves. The human heart contains four valves: tricuspid valve, pulmonary valve, mitral valve and aortic valve. Their main purpose is to keep blood flowing in the proper direction through the heart, and from the heart into the major blood vessels connected to it (the pulmonary artery and the aorta). Heart valves can malfunction for a variety of reasons, which can impede the flow of blood through the valve ( stenosis) and/or let blood flow backwards through the valve ( regurgitation). Both processes put strain on the heart and may lead to serious problems, including heart failure. While some dysfunctional valves can be treated with drugs or repaired, others need to be replaced wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rheumatic Heart Disease
Rheumatic fever (RF) is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a streptococcal throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and occasionally a characteristic non-itchy rash known as erythema marginatum. The heart is involved in about half of the cases. Damage to the heart valves, known as rheumatic heart disease (RHD), usually occurs after repeated attacks but can sometimes occur after one. The damaged valves may result in heart failure, atrial fibrillation and infection of the valves. Rheumatic fever may occur following an infection of the throat by the bacterium ''Streptococcus pyogenes''. If the infection is left untreated, rheumatic fever occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Due to their genetics, some peop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brigham And Women's Hospital
Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two founding members of Mass General Brigham, the largest healthcare provider in Massachusetts. Sunil Eappen serves as the hospital's current president. Brigham and Women's Hospital conducts the second largest (behind MGH) hospital-based research program in the world, with an annual research budget of more than $630 million. Pioneering achievements at BWH have included the world's first successful heart valve operation and the world's first solid organ transplant. In the 2020 ''U.S. News & World Report'' hospital rankings, BWH was ranked second in Massachusetts (behind MGH) and twelfth nationally. History Brigham and Women's Hospital was established with the 1980 merger of three Harvard-affiliated hospita ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elliott Cutler
Elliot Carr Cutler (July 30, 1888 – August 16, 1947) was an American surgeon, military physician, and medical educator. He was Moseley Professor of Surgery at Harvard Medical School, surgeon-in-chief at Peter Bent Brigham Hospital from 1932 to 1947, and a brigadier general in the U.S. Army Medical Corps. Early life Cutler was born on July 30, 1888, in Bangor, Maine. He was the son of George Chalmers Cutler and Mary Franklin Wilson. His father was a lumber merchant. He was named for his maternal grandmother, Mary Elliot Carr (d. 1869), who belonged to a prominent political and mercantile family in Bangor (see Francis Carr). The Carr-Wing House remains a local landmark. Cutler studied at Harvard College and graduated from that institution in 1909. After completing his A.B., he studied at Harvard Medical School (HMS) and received his M.D. ''summa cum laude'' in 1913, ranking first in his class. He studied pathology with Frank Burr Mallory at the Boston City Hospital (now Bosto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
