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Mildew Resistance Locus O
Mildew locus o (MLO) is a plant-specific gene family. Specific members of the Mildew Locus O gene family act as powdery mildew susceptibility factors. Their inactivation, as the result of a loss-of-function mutation, gene knock-out, or knock-down, is associated with a peculiar form of resistance, referred to as ''mlo'' resistance. The ''mlo'' gene family is widely conserved across the plant kingdom with some members evolving as early as the first land plants. Mlo proteins contain seven highly conserved transmembrane domains, as well as a calmodulin-binding domain. ''TaMLO'' genes are the MLOs in ''Triticum aestivum''. MLO genes in tomatoes At least 17 MLO genes exist in tomatoes. They have a protein length of between 270 and 591 amino acids Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alp ...
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Gene Family
A gene family is a set of several similar genes, formed by duplication of a single original gene, and generally with similar biochemical functions. One such family are the genes for human hemoglobin subunits; the ten genes are in two clusters on different chromosomes, called the α-globin and β-globin loci. These two gene clusters are thought to have arisen as a result of a precursor gene being duplicated approximately 500 million years ago. Genes are categorized into families based on shared nucleotide or protein sequences. Phylogenetic techniques can be used as a more rigorous test. The positions of exons within the coding sequence can be used to infer common ancestry. Knowing the sequence of the protein encoded by a gene can allow researchers to apply methods that find similarities among protein sequences that provide more information than similarities or differences among DNA sequences. If the genes of a gene family encode proteins, the term '' protein family'' is often ...
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Transmembrane Domains
A transmembrane domain (TMD) is a membrane-spanning protein domain. TMDs generally adopt an alpha helix topological conformation, although some TMDs such as those in porins can adopt a different conformation. Because the interior of the lipid bilayer is hydrophobic, the amino acid residues in TMDs are often hydrophobic, although proteins such as membrane pumps and ion channels can contain polar residues. TMDs vary greatly in length, sequence, and hydrophobicity, adopting organelle-specific properties. Functions of transmembrane domains Transmembrane domains are known to perform a variety of functions. These include: * Anchoring transmembrane proteins to the membrane. *Facilitating molecular transport of molecules such as ions and proteins across biological membranes; usually hydrophilic residues and binding sites in the TMDs help in this process. * Signal transduction across the membrane; many transmembrane proteins, such as G protein-coupled receptors, receive extracellula ...
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Calmodulin-binding Domain
In molecular biology, calmodulin binding domain (CaMBD) is a protein domain found in small-conductance calcium-activated potassium channels (SK channels). These channels are independent of voltage and gated solely by intracellular Ca2+. They are heteromeric complexes that comprise pore-forming alpha-subunits and the Ca2+-binding protein calmodulin (CaM). CaM Molecular binding, binds to the SK channel through the CaMBD, which is located in an intracellular region of the alpha-subunit immediately carboxy-terminal to the pore. Channel opening is triggered when Ca2+ binds the Ef hand motifs, EF hands in the N-lobe of CaM. The secondary structure, structure of this domain complexed with CaM is known. This domain forms an elongated protein dimer, dimer with a CaM molecule bound at each end; each CaM wraps around three alpha-helices, two from one CaMBD subunit and one from the other. References

{{InterPro content, IPR004178 Protein families ...
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TaMLO
Mildew locus o (MLO) is a plant-specific gene family. Specific members of the Mildew Locus O gene family act as powdery mildew susceptibility factors. Their inactivation, as the result of a loss-of-function mutation, gene knock-out, or knock-down, is associated with a peculiar form of resistance, referred to as ''mlo'' resistance. The ''mlo'' gene family is widely conserved across the plant kingdom with some members evolving as early as the first land plants. Mlo proteins contain seven highly conserved transmembrane domains, as well as a calmodulin-binding domain. ''TaMLO'' genes are the MLOs in ''Triticum aestivum''. MLO genes in tomatoes At least 17 MLO genes exist in tomatoes. They have a protein length of between 270 and 591 amino acids Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alph ...
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Triticum Aestivum
Common wheat (''Triticum aestivum''), also known as bread wheat, is a cultivated wheat species. About 95% of wheat produced worldwide is common wheat; it is the most widely grown of all crops and the cereal with the highest monetary yield. Taxonomy Numerous forms of wheat have evolved under human selection. This diversity has led to confusion in the naming of wheats, with names based on both genetic and morphological characteristics. List of common cultivars * Albimonte * Manital Phylogeny Bread wheat is an allohexaploid (an allopolyploid with six sets of chromosomes: two sets from each of three different species). Of the six sets of chromosomes, two come from ''Triticum urartu'' (einkorn wheat) and two from a species related to ''Aegilops speltoides''. This spontaneous hybridisation created the tetraploid species ''Triticum turgidum'' (an ancestor of wild emmer wheat and durum wheat) 580,000–820,000 years ago. The last two sets of chromosomes came from wild goat-gra ...
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Plant Communications
Plants are predominantly photosynthetic eukaryotes of the kingdom Plantae. Historically, the plant kingdom encompassed all living things that were not animals, and included algae and fungi; however, all current definitions of Plantae exclude the fungi and some algae, as well as the prokaryotes (the archaea and bacteria). By one definition, plants form the clade Viridiplantae (Latin name for "green plants") which is sister of the Glaucophyta, and consists of the green algae and Embryophyta (land plants). The latter includes the flowering plants, conifers and other gymnosperms, ferns and their allies, hornworts, liverworts, and mosses. Most plants are multicellular organisms. Green plants obtain most of their energy from sunlight via photosynthesis by primary chloroplasts that are derived from endosymbiosis with cyanobacteria. Their chloroplasts contain chlorophylls a and b, which gives them their green color. Some plants are parasitic or mycotrophic and have lost the ability ...
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Chinese Academy Of Sciences
The Chinese Academy of Sciences (CAS); ), known by Academia Sinica in English until the 1980s, is the national academy of the People's Republic of China for natural sciences. It has historical origins in the Academia Sinica during the Republican era and was formerly also known by that name. Collectively known as the "Two Academies (两院)" along with the Chinese Academy of Engineering, it functions as the national scientific think tank and academic governing body, providing advisory and appraisal services on issues stemming from the national economy, social development, and science and technology progress. It is headquartered in Xicheng District, Beijing, with branch institutes all over mainland China. It has also created hundreds of commercial enterprises, Lenovo being one of the most famous. CAS is the world's largest research organization. It had 60,000 researchers in 2018 and 114 institutes in 2016, and has been consistently ranked among the top research organizations ...
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Center For Excellence In Molecular Plant Sciences
The Chinese Academy of Sciences (CAS); ), known by Academia Sinica in English until the 1980s, is the national academy of the People's Republic of China for natural sciences. It has historical origins in the Academia Sinica during the Republican era and was formerly also known by that name. Collectively known as the "Two Academies (两院)" along with the Chinese Academy of Engineering, it functions as the national scientific think tank and academic governing body, providing advisory and appraisal services on issues stemming from the national economy, social development, and science and technology progress. It is headquartered in Xicheng District, Beijing, with branch institutes all over mainland China. It has also created hundreds of commercial enterprises, Lenovo being one of the most famous. CAS is the world's largest research organization. It had 60,000 researchers in 2018 and 114 institutes in 2016, and has been consistently ranked among the top research organizations ar ...
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Chinese Society For Plant Biology
Chinese can refer to: * Something related to China * Chinese people, people of Chinese nationality, citizenship, and/or ethnicity **''Zhonghua minzu'', the supra-ethnic concept of the Chinese nation ** List of ethnic groups in China, people of various ethnicities in contemporary China ** Han Chinese, the largest ethnic group in the world and the majority ethnic group in Mainland China, Hong Kong, Macau, Taiwan, and Singapore ** Ethnic minorities in China, people of non-Han Chinese ethnicities in modern China ** Ethnic groups in Chinese history, people of various ethnicities in historical China ** Nationals of the People's Republic of China ** Nationals of the Republic of China ** Overseas Chinese, Chinese people residing outside the territories of Mainland China, Hong Kong, Macau, and Taiwan * Sinitic languages, the major branch of the Sino-Tibetan language family ** Chinese language, a group of related languages spoken predominantly in China, sharing a written script (Chinese c ...
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Cell Press
Cell Press is an all-science publisher of over 50 scientific journals across the life, physical, earth, and health sciences, both independently and in partnership with scientific societies. Many of Cell Press's journals are among the most reputable in their fields. Cell Press was founded and is currently based in Cambridge, MA, and has offices across the United States, Europe, and Asia under its parent company Elsevier. History Benjamin Lewin founded ''Cell'' in January 1974, under the aegis of MIT Press. He then bought the title and established an independent Cell Press in 1986. The company spun off new journals as follows: ''Neuron'' in March 1988; ''Immunity'' in April 1994; and ''Molecular Cell'' in December 1997. Benjamin Lewin left in October 1999, after having sold Cell Press to Elsevier the previous April. Since that time, Cell Press has launched a number of new titles: ''Developmental Cell'' in July 2001; ''Cancer Cell'' in February 2002; ''Cell Metabolism'' in Janua ...
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Tomato
The tomato is the edible berry of the plant ''Solanum lycopersicum'', commonly known as the tomato plant. The species originated in western South America, Mexico, and Central America. The Mexican Nahuatl word gave rise to the Spanish word , from which the English word ''tomato'' derived. Its domestication and use as a cultivated food may have originated with the indigenous peoples of Mexico. The Aztecs used tomatoes in their cooking at the time of the Spanish conquest of the Aztec Empire, and after the Spanish encountered the tomato for the first time after their contact with the Aztecs, they brought the plant to Europe, in a widespread transfer of plants known as the Columbian exchange. From there, the tomato was introduced to other parts of the European-colonized world during the 16th century. Tomatoes are a significant source of umami flavor. They are consumed in diverse ways: raw or cooked, and in many dishes, sauces, salads, and drinks. While tomatoes are fruits†...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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