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Melanistic Mask
A melanistic mask (also referred to as a mask or masking) is a dog coat pattern that gives the appearance of a mask on the dog's face. The hairs on the muzzle, and sometimes entire face or ears, are colored by eumelanin instead of pheomelanin pigment. Eumelanin is typically black, but may instead be brown, dark gray, or light gray-brown. Pheomelanin ranges in color from pale cream to mahogany. The trait is caused by M264V (''EM''), a completely dominant allele (form) of the melanocortin 1 receptor gene. Appearance At minimum, a melanistic mask will appear on the muzzle, and may also be visible on the eartips, entire ears, or entire face. Hairs in those areas will be colored by eumelanin instead of pheomelanin pigment, making it look as though the dog has a mask on its face. Eumelanin is usually black, but may instead be liver (also known as chocolate; dark brown), blue (also known as slate; dark grey), or isabella (also known as lilac; light grey-brown); accordingly, a mask ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pug Portrait
The Pug is a breed of dog originally from China, with physically distinctive features of a wrinkly, short-muzzled face and curled tail. The breed has a fine, glossy coat that comes in a variety of colors, most often light brown (fawn) or black, and a compact, square body with well developed and thick muscles all over the body. Pugs were brought from China to Europe in the sixteenth century and were popularized in Western Europe by the House of Orange of the Netherlands, and the House of Stuart. In the United Kingdom, in the nineteenth century, Queen Victoria developed a passion for pugs which she passed on to other members of the Royal Family. Pugs are known for being sociable and gentle companion dogs. The American Kennel Club describes the breed's personality as "even-tempered and charming". Pugs remain popular into the twenty-first century, with some famous celebrity owners. Description Physical characteristics While the pugs that are depicted in eighteenth century p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brindle
Brindle is a coat (animal), coat coloring pattern in animals, particularly dogs, cattle, guinea pigs, Cat, cats, and, rarely, horses. It is sometimes described as "tiger-striped", although the brindle pattern is more subtle than that of a tiger's coat. Brindle typically appears as black stripes on a red base. The stripes are eumelanin (black/brown pigment) and the base is phaeomelanin (red/yellow pigment), so the appearance of those pigments can be changed by any of the genes which usually affect them. * Eumelanin (the pigment making up the stripes) can be affected by: merle (and harlequin), liver, dilution, greying, and recessive red. * Phaeomelanin (the pigment making up the base) can be affected by: Intensity locus. And of course, white markings and ticking can occur on any brindle dog. Brindle is caused by a complex gene process and is technically a form of mosaicism, where some cells express one allele (KB) and other cells express a different allele (ky), a little like t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dog Anatomy
Dog anatomy comprises the anatomical studies of the visible parts of the body of a domestic dog. Details of structures vary tremendously from breed to breed, more than in any other animal species, wild or domesticated, as dogs are highly variable in height and weight. The smallest known adult dog was a Yorkshire Terrier that stood only at the shoulder, in length along the head and body, and weighed only . The heaviest dog was an English Mastiff named Zorba which weighed . The tallest known adult dog is a Great Dane that stands at the shoulder. Anatomy Source: Muscles The following is a list of the muscles in the dog, along with their origin, insertion, action and innervation. ''Extrinsic muscles of the thoracic limb and related structures:'' Descending superficial pectoral: originates on the first sternebrae and inserts on the greater tubercle of the humerus. It both adducts the limb and also prevents the limb from being abducted during weight bearing. It is innervated b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Border Collie
The Border Collie is a Scottish breed of herding dog of medium size. Widely considered to be the most intelligent dog breed, they are descended from landrace sheepdogs once found all over the British Isles, but became standardised in the Anglo-Scottish border region. They are now mostly used as working dogs to herd livestock, specifically sheep. Border Collies are extremely energetic, acrobatic, and athletic. They frequently compete with great success in sheepdog trials and a range of dog sports like dog obedience, disc dog, herding and dog agility. Border Collies continue to be employed in their traditional work of herding livestock throughout the world and are kept as pets. Description In general, Border Collies are medium-sized dogs with a moderate amount of coat, which is more often thick and prone to shedding. They have a double coat that varies from smooth to rough and is occasionally curled. While black and white is the most commonly seen colour pattern of the Bor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kerry Blue Terrier
The Kerry Blue Terrier (also known as the Irish Blue Terrier) ( gle, An Brocaire Gorm) is a breed of dog. Originally bred to control vermin including rats, rabbits, badgers, foxes, otters and hares, over time the Kerry became a general working dog used for a variety of jobs including herding cattle and sheep, and as a guard dog. Today the Kerry has spread around the world as a companion and working dog. Despite a Kerry Blue winning Crufts (the most prestigious UK dog show) in 2000, it remains an "unfashionable" breed, and is distinctly uncommon; however, it is not as threatened as some of the other terrier breeds such as the Skye Terrier, Sealyham Terrier, and Dandie Dinmont Terrier. Description Appearance Some characteristics of the Kerry Blue Terrier include a long head, flat skull, deep chest, and a soft wavy-to-curly coat that comes in several shades of "blue", the general term outside this breed being progressive grey. Puppies are born black; the blue appears gradually as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dogue De Bordeaux
The Dogue de Bordeaux, Bordeaux Mastiff, French Mastiff or Bordeauxdog is a large French mastiff breed. A typical brachycephalic mastiff breed, the Bordeaux is a very powerful dog, with a very muscular body. This muscular breed has been put to work pulling carts, transporting heavy objects, and guarding flocks. History The Dogue de Bordeaux was known in France as early as the 14th century, particularly in southern France in the region around Bordeaux. Hence, the city lent its name to this large dog. The breed was first exhibited in France in 1863 after which time it gained in popularity not only in their home country but in other parts of the world. The first record of the Dogue de Bordeaux in the UK can be seen in the Kennel Club Gazette in 1897. The breed was officially recognised by the Kennel Club (UK) in 1997 but it was not until 2001 that the Kennel Club (UK) accepted an interim breed standard. A uniform breed type of the Bordeaux dog did not exist before about 1920. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whippet
The Whippet is a dog breed of medium size. It is a sighthound breed that originated in England, descended from the Greyhound. Whippets today still strongly resemble a smaller Greyhound. Part of the hound group, Whippets have relatively few health problems other than arrhythmia. Whippets also participate in dog sports such as lure coursing, agility, dock diving and flyball. The name is derived from an early 17th-century word, now obsolete, meaning "to move briskly". There has been continuity in describing Greyhound-types of different sizes: large, medium and small, recorded in hunting manuals and works on natural history from the Middle Ages. Edward of Norwich, 2nd Duke of York confirmed in his early 15th-century translation and additions to the original late 14th-century French ''Livre de chasse'' the advantage of maintaining the great, the middle, and the small size of greyhound for different sorts of game. The English physician and academic John Caius refers in his 16th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agouti Gene
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. It is responsible for the distribution of melanin pigment in mammals. Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). This interaction is responsible for making distinct light and dark bands in the hairs of animals such as the agouti, which the gene is named after. In other species such as horses, agouti signalling is responsible for determining which parts of the body will be red or black. Mice with wildtype agouti will be grey, with each hair being partly yellow and partly black. Loss of function mutations in mice and other species cause black fur coloration, while mutations causing expression throughout the whole body in mice cause yellow fur and obesity. The agouti-signaling protein (ASIP) is a competitive antagonist with alpha-Melanocyte-stimulating hormon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melanocyte-stimulating Hormone
The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary gland. Synthetic analogues of α-MSH, such as afamelanotide (melanotan I; Scenesse), melanotan II, and bremelanotide (PT-141), have been developed and researched. Biosynthesis The various forms of MSH are generated from different cleavages of the proopiomelanocortin protein, which also yields other important neuropeptides like adrenocorticotropic hormone. Melanocytes in skin make and secrete MSH in response to ultraviolet light, where it increases synthesis of melanin. Some neurons in arcuate nucleus of the hypothalamus make and secrete α-MSH in response to leptin; α-MSH is also m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UC Davis School Of Veterinary Medicine
The University of California, Davis, School of Veterinary Medicine is the largest veterinary school in the United States. Established in 1948, the school is the primary health resource for California's various animal populations. In 2020, the school was again ranked No. 1 in the United States by '' U.S. News & World Report'' and in 2021, ranked No. 2 in the world bQS World University Rankings The school is located in the southwest corner of the main campus of the University of California, Davis. The current Dean of Veterinary Medicine is Dr. Mark Stetter. The School focuses on students of the professional Doctor of Veterinary Medicine program, the Master of Preventive Veterinary Medicine program, graduate clinical residency programs, and graduate academic MS and PhD programs. The School of Veterinary Medicine provides educational, research, clinical service, and public service programs to advance the health and care of animals, the health of the environment, and public health. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Locus (genetics)
In genetics, a locus (plural loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of protein-coding genes in a complete haploid set of 23 chromosomes is estimated at 19,000–20,000. Genes may possess multiple variants known as alleles, and an allele may also be said to reside at a particular locus. Diploid and polyploid cells whose chromosomes have the same allele at a given locus are called homozygous with respect to that locus, while those that have different alleles at a given locus are called heterozygous. The ordered list of loci known for a particular genome is called a gene map. Gene mapping is the process of determining the specific locus or loci responsible for producing a particular phenotype or biological trait. Association mapping, also known as "linkage disequilibrium mapping", is a method of ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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