Medicines Discovery Catapult
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Medicines Discovery Catapult
The Medicines Discovery Catapult (MDC) is the United Kingdom's catapult centre for medicine research and innovation, headquartered at Alderley Park in Cheshire. History The intention to form the company was announced by the Chancellor on 13 July 2015 with funding of £5m, on a visit to Cheshire. It would be part of the Northern Powerhouse initiative. The Medicines Technologies Catapult was established in December 2015, funded by a £10m grant from Innovate UK and based at the Alderley Park science park in Cheshire. On 1 March 2016 its name changed to the Medicines Discovery Catapult. Further funding of approximately £10m per year was secured from Innovate UK for the years 2018 to 2023. Precision Medicine Catapult The PMC was based in Cambridge and had regional centres of excellence at Belfast, Glasgow, Cardiff, Oxford, Leeds and Manchester. It worked with precision medicine. It started from April 2015, and worked with regional parts of the Diagnostic Evidence Cooperative and ...
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Catapult Centres
Catapult centres are organisations set up from 2011 onwards by Innovate UK in the United Kingdom to promote research and development through business-led collaboration between scientists and engineers to exploit market opportunities. They receive grants from public funds but are also expected to seek commercial funding. History In 2010, the Department for Business, Innovation and Skills commissioned a report on technical innovation from Hermann Hauser, an entrepreneur who had been active in information technology since 1978. The report recommended the establishment of a number of Technology and Innovation Centres. Each centre received "core" funding of £10 million per year for five years via the Technology Strategy Board (which since 2014 has used the name Innovate UK). Since 2018, Innovate UK has been a council of United Kingdom Research and Innovation, a non-departmental public body. It was intended that the long-term split would be one-third core funding, one-third commer ...
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European Lead Factory
The European Lead Factory is a public-private partnership that aims to accelerate early drug discovery in Europe. The European Lead Factory is funded by the Innovative Medicines Initiative and consists of a pan-European consortium that includes 7 pharmaceutical companies as well as partners from academia and small and medium-sized enterprises (SMEs). Drug discovery platform The European Lead Factory is operational since 2013 and consists of two main components: the Joint European Compound Library and the European Screening Centre. Together these elements provide a platform for pharmaceutical researchers in Europe to identify drug discovery starting points, by connecting innovative drug targets to high-quality small molecules. The result is defined in a ‘hit list’: a number of compounds that show affinity for the target. The compounds on those lists can either be used as probes to better understand biological pathways or as starting points for lead discovery efforts for nove ...
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Pharmacognosy
Pharmacognosy is the study of medicinal plants and other natural substances as sources of drugs. The American Society of Pharmacognosy defines pharmacognosy as "the study of the physical, chemical, biochemical, and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources". Description The word "pharmacognosy" is derived from two Greek words: ', (drug), and '' gnosis'' (knowledge) or the Latin verb '' cognosco'' (', 'with', and , 'know'; itself a cognate of the Greek verb , , meaning 'I know, perceive'), meaning 'to conceptualize' or 'to recognize'. The term "pharmacognosy" was used for the first time by the Austrian physician Schmidt in 1811 and by Anotheus Seydler in 1815 in a work titled ''Analecta Pharmacognostica''. Originally—during the 19th century and the beginning of the 20th century—"pharmacognosy" was used to define the branch of medicine or commodity ...
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Pharmaceutical Industry In The United Kingdom
The pharmaceutical industry in the United Kingdom directly employs around 73,000 people and in 2007 contributed £8.4 billion to the UK's GDP and invested a total of £3.9 billion in research and development. In 2007 exports of pharmaceutical products from the UK totalled £14.6 billion, creating a trade surplus in pharmaceutical products of £4.3 billion. UK Pharmaceutical employment of 73,000 in 2017 compares to 114,000 as of 2015 in Germany, 92,000 as of 2014 in France and 723,000 in the European Union as a whole. In the United States 281,440 people work in pharmaceutical industry as of 2016. The UK is home to GlaxoSmithKline and AstraZeneca, respectively the world's fifth- and sixth-largest pharmaceutical companies measured by 2009 market share. It is also home to the multinational Hikma Pharmaceuticals. Foreign companies with a major presence in the UK pharmaceutical industry include Pfizer, Novartis, Hoffmann–La Roche and Eisai. One in five of the world's biggest-selling ...
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Organisations Based In Cheshire
An organization or organisation (Commonwealth English; see spelling differences), is an entity—such as a company, an institution, or an association—comprising one or more people and having a particular purpose. The word is derived from the Greek word ''organon'', which means tool or instrument, musical instrument, and organ. Types There are a variety of legal types of organizations, including corporations, governments, non-governmental organizations, political organizations, international organizations, armed forces, charities, not-for-profit corporations, partnerships, cooperatives, and educational institutions, etc. A hybrid organization is a body that operates in both the public sector and the private sector simultaneously, fulfilling public duties and developing commercial market activities. A voluntary association is an organization consisting of volunteers. Such organizations may be able to operate without legal formalities, depending on jurisdiction, incl ...
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Medicinal Chemistry
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). Medicinal chemistry is a highly interdisciplinary science combining organic chemistry with biochemistry, computational chemistry, pharmacology, molecular biology, statistics, and physical chemistry. Compounds used as medicines are most often organic compounds, which are often divided into the broad classes of small organic molecules (e.g., atorvastatin, fluticasone, clopidogrel) and "biologics" (infliximab, erythropoietin, insulin glargine), the latter of which are most often medicinal preparations of proteins (natural and recombinant anti ...
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Medical Research Organizations
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an an ...
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Medical And Health Organisations Based In The United Kingdom
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an anci ...
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Health In Cheshire
Health, according to the World Health Organization, is "a state of complete physical, Mental health, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World Health Organization''– ''Basic Documents'', Forty-fifth edition, Supplement, October 2006. A variety of definitions have been used for different purposes over time. Health can be promoted by encouraging healthful activities, such as regular physical exercise and adequate sleep, and by reducing or avoiding unhealthful activities or situations, such as smoking or excessive Stress (biology), stress. Some factors affecting health are due to Agency (sociology), individual choices, such as whether to engage in a high-risk behavior, while others are due to Social structure, structural causes, such as whether the society is arranged in a way that makes it easier or harder for people to get necessary healthcare services. Still, other factors are be ...
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Government Agencies Established In 2015
A government is the system or group of people governing an organized community, generally a state. In the case of its broad associative definition, government normally consists of legislature, executive, and judiciary. Government is a means by which organizational policies are enforced, as well as a mechanism for determining policy. In many countries, the government has a kind of constitution, a statement of its governing principles and philosophy. While all types of organizations have governance, the term ''government'' is often used more specifically to refer to the approximately 200 independent national governments and subsidiary organizations. The major types of political systems in the modern era are democracies, monarchies, and authoritarian and totalitarian regimes. Historically prevalent forms of government include monarchy, aristocracy, timocracy, oligarchy, democracy, theocracy, and tyranny. These forms are not always mutually exclusive, and mixed gover ...
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British Medical Research
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, the English language as spoken and written in the United Kingdom or, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *''Brit(ish)'', a 2018 memoir by Afua Hirsch *People or things associated with: ** Great Britain, an island ** United Kingdom, a sovereign state ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) See also * Terminology of the British Isles * Alternative names for the British * English (other) * Britannic (other) * British Isles * Brit (other) * B ...
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Borough Of Cheshire East
A borough is an administrative division in various English-speaking countries. In principle, the term ''borough'' designates a self-governing walled town, although in practice, official use of the term varies widely. History In the Middle Ages, boroughs were settlements in England that were granted some self-government; burghs were the Scottish equivalent. In medieval England, boroughs were also entitled to elect members of parliament. The use of the word ''borough'' probably derives from the burghal system of Alfred the Great. Alfred set up a system of defensive strong points (Burhs); in order to maintain these particular settlements, he granted them a degree of autonomy. After the Norman Conquest, when certain towns were granted self-governance, the concept of the burh/borough seems to have been reused to mean a self-governing settlement. The concept of the borough has been used repeatedly (and often differently) throughout the world. Often, a borough is a single town with ...
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