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Marco Antonio Zago
Marco Antonio Zago (born January 11, 1946, in Birigüi, São Paulo) is a Brazilian physician and prominent medical scientist, who is active in the fields of hereditary diseases of the blood (hemoglobins, clotting, thrombosis), molecular basis of cancer and human population genetics. Aside from working directly as scientes, he has been president of the Brazilian National Research Council (CNPq) and dean of the University of São Paulo. He's now the president of the São Paulo Research Foundation (São Paulo Research Foundation, Fapesp). Dr. Zago graduated in Medicine from the School of Medicine of Ribeirão Preto of the University of São Paulo in 1970, where he received the M.Sc. degree in medicine (1973) and the Ph.D. degree (1975), under the supervision of Professor Cássio Bottura, one of the most outstanding Brazilian hematologist and cytogeneticist. After his post-doctoral training at the Oxford University, in the laboratories of Professor Sir David J. Wetherall, whose group ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marco Antonio Zago 11072007
Marco may refer to: People * Marco (given name), people with the given name Marco * Marco (actor) (born 1977), South Korean model and actor * Georg Marco (1863–1923), Romanian chess player of German origin * Tomás Marco (born 1942), Spanish composer and writer on music Places * Marco, Ceará, Brazil, a municipality * Marco, New Zealand, a locality in the Taranaki Region * Marco, Indiana, United States, an unincorporated town * Marco, Missouri, United States, an unincorporated community * Marco Island, Florida, United States, a city and an island Science and technology * Mars Cube One (MarCO), a pair of small satellites which fly by Mars in 2018 * MARCO, a macrophage receptor protein that in humans is encoded by the MARCO gene * Mid-Atlantic Regional Council on the Ocean (MARCO) * Marco, the official window manager of MATE (software), MATE Arts and entertainment * ''Marco: 3000 Leagues in Search of Mother'', a 1976 Japanese anime series, directed by Isao Takahata * Marco (film ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemophilia
Haemophilia, or hemophilia (), is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding for a longer time after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain. Those with a mild case of the disease may have symptoms only after an accident or during surgery. Bleeding into a joint can result in permanent damage while bleeding in the brain can result in long term headaches, seizures, or a decreased level of consciousness. There are two main types of haemophilia: haemophilia A, which occurs due to low amounts of clotting factor VIII, and haemophilia B, which occurs due to low levels of clotting factor IX. They are typically inherited from one's parents through an X chromosome carrying a nonfunctional gene. Rarely a new mutation may occur during early development or haemophilia may develop later in life due to antibodies forming against ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gamma Globin
Gamma (uppercase , lowercase ; ''gámma'') is the third letter of the Greek alphabet. In the system of Greek numerals it has a value of 3. In Ancient Greek, the letter gamma represented a voiced velar stop . In Modern Greek, this letter represents either a voiced velar fricative or a voiced palatal fricative (while /g/ in foreign words is instead commonly transcribed as γκ). In the International Phonetic Alphabet and other modern Latin-alphabet based phonetic notations, it represents the voiced velar fricative. History The Greek letter Gamma Γ is a grapheme derived from the Phoenician letter (''gīml'') which was rotated from the right-to-left script of Canaanite to accommodate the Greek language's writing system of left-to-right. The Canaanite grapheme represented the /g/ phoneme in the Canaanite language, and as such is cognate with '' gimel'' ג of the Hebrew alphabet. Based on its name, the letter has been interpreted as an abstract representation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Point Mutation
A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism's genome. Point mutations have a variety of effects on the downstream protein product—consequences that are moderately predictable based upon the specifics of the mutation. These consequences can range from no effect (e.g. synonymous mutations) to deleterious effects (e.g. frameshift mutations), with regard to protein production, composition, and function. Causes Point mutations usually take place during DNA replication. DNA replication occurs when one double-stranded DNA molecule creates two single strands of DNA, each of which is a template for the creation of the complementary strand. A single point mutation can change the whole DNA sequence. Changing one purine or pyrimidine may change the amino acid that the nucleotides code for. Point mutations may arise from spontaneous mutations that occur during DNA replication. The rate of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anemia
Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen due to a lower than normal number of red blood cells, or a reduction in the amount of hemoglobin. When anemia comes on slowly, the symptoms are often vague, such as tiredness, weakness, shortness of breath, headaches, and a reduced ability to exercise. When anemia is acute, symptoms may include confusion, feeling like one is going to pass out, loss of consciousness, and increased thirst. Anemia must be significant before a person becomes noticeably pale. Symptoms of anemia depend on how quickly hemoglobin decreases. Additional symptoms may occur depending on the underlying cause. Preoperative anemia can increase the risk of needing a blood transfusion following surgery. Anemia can be temporary or long term and can range from mild to severe. Anemia can be caused by blood loss, decreased red blood cell production, and increased red blood cell breakdown. Causes o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Diseases
:''This is an incomplete list, which may never be able to satisfy certain standards for completion.'' There are many conditions of or affecting the human hematologic system—the biological system that includes plasma, platelets, leukocytes, and erythrocytes, the major components of blood and the bone marrow. Anemias An anemia is a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocyte ... in the blood.MedicineNet.com Definition of Anemia Last Editorial Review: 12/9/2000 Retrieved March 27, 2011 [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research
Research is "creativity, creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, Discovery (observation), discovery, interpretation (philosophy), interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemology, epistemologies, which vary considerably both within and between humanities and sciences. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thalassemia
Thalassemias are inherited blood disorders characterized by decreased hemoglobin production. Symptoms depend on the type and can vary from none to severe. Often there is mild to severe anemia (low red blood cells or hemoglobin). Anemia can result in feeling tired and pale skin. There may also be bone problems, an enlarged spleen, yellowish skin, and dark urine. Slow growth may occur in children. Thalassemias are genetic disorders inherited from a person's parents. There are two main types, alpha thalassemia and beta thalassemia. The severity of alpha and beta thalassemia depends on how many of the four genes for alpha globin or two genes for beta globin are missing. Diagnosis is typically by blood tests including a complete blood count, special hemoglobin tests, and genetic tests. Diagnosis may occur before birth through prenatal testing. Treatment depends on the type and severity. Treatment for those with more severe disease often includes regular blood transfusions, iron chel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David J
David John Haskins (born 24 April 1957, Northampton, Northamptonshire, England), better known as David J, is a British alternative rock musician, producer, and writer. He is the bassist for the gothic rock band Bauhaus and for Love and Rockets. He has composed the scores for a number of plays and films, and also wrote and directed his own plays, ''Silver for Gold (The Odyssey of Edie Sedgwick)'', in 2008, which was restaged at REDCAT in Los Angeles in 2011, and ''The Chanteuse and The Devil's Muse'' in 2011. His artwork has been shown in galleries internationally, and he has been a resident DJ at venues such as the Knitting Factory. David J has released a number of singles and solo albums, and in 1990 he released one of the first No. 1 hits on the then nascent Modern Rock Tracks charts, with "I'll Be Your Chauffeur". His most recent single, "The Day That David Bowie Died" entered the UK vinyl singles chart at number 4 in 2016. The track appears on his double album, ''Vaga ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford University
Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the University of Oxford, the oldest university in the English-speaking world; it has buildings in every style of English architecture since late Anglo-Saxon. Oxford's industries include motor manufacturing, education, publishing, information technology and science. History The history of Oxford in England dates back to its original settlement in the Saxon period. Originally of strategic significance due to its controlling location on the upper reaches of the River Thames at its junction with the River Cherwell, the town grew in national importance during the early Norman period, and in the late 12th century became home to the fledgling University of Oxford. The city was besieged during The Anarchy in 1142. The university rose to domina ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
