Marc Lacroix (biochemist)
Marc Guy Albert Marie Lacroix (; born 28 April 1963 in Verviers, Wallonia, Belgium) is a biochemist (educated at University of Liège) and a researcher who specializes in breast cancer biology, metastasis and therapy. He works at Institut Jules Bordet (Brussels, Belgium). He lives in Baelen Earlier work Breast cancer cells (BCC) frequently metastasize to the skeleton, where they lead to tumor-induced osteolysis and subsequent morbidity. Marc Lacroix has investigated the interrelationships between BCC and bone cells (osteoblasts, the bone-building cells, and osteoclasts, the bone-degrading cells). With colleagues, he discovered that BCC produce soluble factors increasing osteoclast activity, notably interleukin-11, the production of which is reduced by the cyclooxygenase inhibitor aspirin. BCC also reduce the proliferation of osteoblasts and their production of collagen, the main protein component of bone. Marc Lacroix also examined the response BCC to the anti-osteolytic agent ...
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