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MIPModDB
MIPModDB is a database of comparative protein structure models of MIP (Major intrinsic proteins) family of proteins. See also * Major intrinsic proteins Major intrinsic proteins comprise a large superfamily of transmembrane protein channels that are grouped together on the basis of homology. The MIP superfamily includes three subfamilies: aquaporins, aquaglyceroporins and S-aquaporins. # The aqua ... References External links * http://bioinfo.iitk.ac.in/MIPModDB. Biological databases Protein domains Protein families Transmembrane proteins {{Biodatabase-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Major Intrinsic Proteins
Major intrinsic proteins comprise a large superfamily of transmembrane protein channels that are grouped together on the basis of homology. The MIP superfamily includes three subfamilies: aquaporins, aquaglyceroporins and S-aquaporins. # The aquaporins (AQPs) are water selective. # The aquaglyceroporins are permeable to water, but also to other small uncharged molecules such as glycerol. # The third subfamily, with little conserved amino acid sequences around the NPA boxes, include ' superaquaporins' (S-aquaporins). The phylogeny of insect MIP family channels has been published. Families There are two families that belong to thMIP Superfamily 1.A.8- The Major Intrinsic Protein (MIP) Family 1.A.16- The Formate-Nitrite Transporter (FNT) Family The Major Intrinsic Protein Family (TC# 1.A.8) The MIP family is large and diverse, possessing thousands of members that form transmembrane channels. These channel proteins function in transporting water, small carbohydrates (e.g., gly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Database
In computing, a database is an organized collection of data stored and accessed electronically. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases spans formal techniques and practical considerations, including data modeling, efficient data representation and storage, query languages, security and privacy of sensitive data, and distributed computing issues, including supporting concurrent access and fault tolerance. A database management system (DBMS) is the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS software additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an appli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indian Institute Of Technology Kanpur, INDIA
The Indian Institute of Technology Kanpur (IIT Kanpur) Hindi: भारतीय प्रौद्योगिकी संस्थान कानपुर) is a public institute of technology located in Kanpur, Uttar Pradesh, India. It was declared to be an Institute of National Importance by the Government of India under the Institutes of Technology Act. The institution was established in 1959. As one of the first Indian Institutes of Technology, the institute was created with the assistance of a consortium of nine US research universities as part of the Kanpur Indo-American Programme (KIAP). History IIT Kanpur was established by an Act of Parliament in 1960 by the Government of India. The institute was started in December 1959 in a room in the canteen building of the Harcourt Butler Technological Institute at Agricultural Gardens in Kanpur. In 1963, the institute moved to its present location, on the Grand Trunk Road near Kalyanpur locality in Kanpur district. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Department Of Biological Sciences And Bioengineering
Department may refer to: * Departmentalization, division of a larger organization into parts with specific responsibility Government and military * Department (administrative division), a geographical and administrative division within a country, for example: **Departments of Colombia, a grouping of municipalities ** Departments of France, administrative divisions three levels below the national government **Departments of Honduras ** Departments of Peru, name given to the subdivisions of Peru until 2002 ** Departments of Uruguay * Department (United States Army), corps areas of the U.S. Army prior to World War I *Fire department, a public or private organization that provides emergency firefighting and rescue services * Ministry (government department), a specialized division of a government *Police department, a body empowered by the state to enforce the law *Department (naval) administrative/functional sub-unit of a ship's company. Other uses * ''Department'' (film), a 2012 Bol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Databases
Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis. They contain information from research areas including genomics, proteomics, metabolomics, microarray gene expression, and phylogenetics. Information contained in biological databases includes gene function, structure, localization (both cellular and chromosomal), clinical effects of mutations as well as similarities of biological sequences and structures. Biological databases can be classified by the kind of data they collect (see below). Broadly, there are molecular databases (for sequences, molecules, etc.), functional databases (for physiology, enzyme activities, phenotypes, ecology etc), taxonomic databases (for species and other taxonomic ranks), images and other media, or specimens (for museum collections etc.) Databases are important tools in assisting scientists to analyze and explain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Domains
In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest. Each domain forms a compact folded three-dimensional structure. Many proteins consist of several domains, and a domain may appear in a variety of different proteins. Molecular evolution uses domains as building blocks and these may be recombined in different arrangements to create proteins with different functions. In general, domains vary in length from between about 50 amino acids up to 250 amino acids in length. The shortest domains, such as zinc fingers, are stabilized by metal ions or disulfide bridges. Domains often form functional units, such as the calcium-binding EF hand domain of calmodulin. Because they are independently stable, domains can be "swapped" by genetic engineering between one protein and another to make chimeric proteins. Background The concept of the domain was first proposed in 1973 by Wetlaufer after ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Families
A protein family is a group of evolutionarily related proteins. In many cases, a protein family has a corresponding gene family, in which each gene encodes a corresponding protein with a 1:1 relationship. The term "protein family" should not be confused with family as it is used in taxonomy. Proteins in a family descend from a common ancestor and typically have similar three-dimensional structures, functions, and significant sequence similarity. The most important of these is sequence similarity (usually amino-acid sequence), since it is the strictest indicator of homology and therefore the clearest indicator of common ancestry. A fairly well developed framework exists for evaluating the significance of similarity between a group of sequences using sequence alignment methods. Proteins that do not share a common ancestor are very unlikely to show statistically significant sequence similarity, making sequence alignment a powerful tool for identifying the members of protein familie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
