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Lumbrokinase
Lumbrokinase is a fibrinolytic enzyme present in the earthworm '' Lumbricus bimastus''. It is a clinically approved and proven antithrombotic An antithrombotic agent is a drug that reduces the formation of blood clots (thrombi).http://cancerweb.ncl.ac.uk/cgi-bin/omd?antithrombotic Antithrombotics can be used therapeutically for prevention ( primary prevention, secondary prevention) or ... agent in Asia. References Antithrombotic agents {{enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibrinolytic
Fibrinolysis is a process that prevents blood clots from growing and becoming problematic. Primary fibrinolysis is a normal body process, while secondary fibrinolysis is the breakdown of clots due to a medicine, a medical disorder, or some other cause.Dugdale, David et al.Primary or secondary fibrinolysis, Medline Plus. Retrieved 7 August 2011. In fibrinolysis, a fibrin clot, the product of coagulation, is broken down. Its main enzyme plasmin cuts the fibrin mesh at various places, leading to the production of circulating fragments that are cleared by other proteases or by the kidney and liver. Physiology Plasmin is produced in an inactive form, plasminogen, in the liver. Although plasminogen cannot cleave fibrin, it still has an affinity for it, and is incorporated into the clot when it is formed. Tissue plasminogen activator (t-PA) and urokinase are the agents that convert plasminogen to the active plasmin, thus allowing fibrinolysis to occur. t-PA is released into the blood ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the react ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Earthworm
An earthworm is a terrestrial invertebrate that belongs to the phylum Annelida. They exhibit a tube-within-a-tube body plan; they are externally segmented with corresponding internal segmentation; and they usually have setae on all segments. They occur worldwide where soil, water, and temperature allow. Earthworms are commonly found in soil, eating a wide variety of organic matter. This organic matter includes plant matter, living protozoa, rotifers, nematodes, bacteria, fungi, and other microorganisms. An earthworm's digestive system runs the length of its body. An earthworm respires (breathes) through its skin. It has a double transport system made of coelomic fluid that moves within the fluid-filled coelom and a simple, closed circulatory system. It has a central and peripheral nervous system. Its central nervous system consists of two ganglia above the mouth, one on either side, connected to a nerve running along its length to motor neurons and sensory cells in ea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lumbricus Bimastus
The genus ''Lumbricus'' contains some of the most commonly seen earthworms in Europe among its nearly 700 valid species. Characteristics of some commonly encountered species are: * ''Lumbricus rubellus'' is usually reddish brown or reddish violet, iridescent dorsally, and pale yellow ventrally. They are usually about 25–105 mm in length, and have around 95-120 segments. * '' Lumbricus castaneus'' varies from chesnut to violet brown; brown or yellow ventrally, and has an orange clitellum. They are usually about 30–70 mm long, and have around 82–100 segments. * ''Lumbricus terrestris'' has several common names, including common earthworm, nightcrawler, and dew worm. It is strongly pigmented, brown-red dorsally, and yellowish ventrally. Setae are widely paired at both ends of the body. It is about 90–300 mm long, and has around 110–160 segments. * '' Lumbricus festivus'' is not found in large numbers. It is red-brown, lighter ventrally, iridescent dorsally. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antithrombotic
An antithrombotic agent is a drug that reduces the formation of blood clots (thrombi).http://cancerweb.ncl.ac.uk/cgi-bin/omd?antithrombotic Antithrombotics can be used therapeutically for prevention ( primary prevention, secondary prevention) or treatment of a dangerous blood clot (acute thrombus). In the U.S., the American College of Chest Physicians publishes clinical guidelines for clinicians for the use of these drugs to treat and prevent a variety of diseases. Processes Different antithrombotics affect different blood clotting processes: * Antiplatelet drugs limit the migration or aggregation of platelets. * Anticoagulants limit the ability of the blood to clot. * Thrombolytic drugs act to dissolve clots after they have formed. See also * Direct Xa inhibitor Direct factor Xa inhibitors (xabans) are anticoagulants (blood thinning drugs), used to both treat and prevent blood clots in veins, and prevent stroke and embolism in people with atrial fibrillation (AF). Medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
