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Literature-based Discovery
Literature-based discovery (LBD), also called literature-related discovery (LRD) is a form of knowledge extraction and automated hypothesis generation that uses papers and other academic publications (the "literature") to find new relationships between existing knowledge (the "discovery"). Literature-based discovery aims to discover new knowledge by connecting information which have been explicitly stated in literature to deduce connections which have not been explicitly stated. LBD can help researchers to quickly discover and explore hypotheses as well as gain information on relevant advances inside and outside of their niches and increase interdisciplinary information sharing. The most basic and widespread type of LBD is called the ABC paradigm because it centers around three concepts called A, B and C. It states that if there is a connection between A and B and one between B and C, then there is one between A and C which, if not explicitly stated, is yet to be explored. Histo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swanson Linking
Literature-based discovery (LBD), also called literature-related discovery (LRD) is a form of knowledge extraction and automated hypothesis generation that uses papers and other academic publications (the "literature") to find new relationships between existing knowledge (the "discovery"). Literature-based discovery aims to discover new knowledge by connecting information which have been explicitly stated in literature to deduce connections which have not been explicitly stated. LBD can help researchers to quickly discover and explore hypotheses as well as gain information on relevant advances inside and outside of their niches and increase interdisciplinary information sharing. The most basic and widespread type of LBD is called the ABC paradigm because it centers around three concepts called A, B and C. It states that if there is a connection between A and B and one between B and C, then there is one between A and C which, if not explicitly stated, is yet to be explored. Histo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Graph Theory
In mathematics, graph theory is the study of ''graphs'', which are mathematical structures used to model pairwise relations between objects. A graph in this context is made up of '' vertices'' (also called ''nodes'' or ''points'') which are connected by '' edges'' (also called ''links'' or ''lines''). A distinction is made between undirected graphs, where edges link two vertices symmetrically, and directed graphs, where edges link two vertices asymmetrically. Graphs are one of the principal objects of study in discrete mathematics. Definitions Definitions in graph theory vary. The following are some of the more basic ways of defining graphs and related mathematical structures. Graph In one restricted but very common sense of the term, a graph is an ordered pair G=(V,E) comprising: * V, a set of vertices (also called nodes or points); * E \subseteq \, a set of edges (also called links or lines), which are unordered pairs of vertices (that is, an edge is associated with t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evaluation Measures (information Retrieval)
Evaluation measures for an information retrieval (IR) system assess how well an index, search engine or database returns results from a collection of resources that satisfy a user's query. They are therefore fundamental to the success of information systems and digital platforms. The success of an IR system may be judged by a range of criteria including relevance, speed, user satisfaction, usability, efficiency and reliability. However the most important factor in determining a systems effectiveness for users is the overall relevance of results retrieved in response to a query. Evaluation measures may be categorised in various ways including offline or online, user-based or system-based and include methods such as observed user behaviour, test collections, precision and recall, and scores from prepared benchmark test sets. Evaluation for an information retrieval system should also include a validation of the measures used, i.e. an assessment of how well they measure what they are i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantic Relationship
Contemporary ontologies share many structural similarities, regardless of the ontology language in which they are expressed. Most ontologies describe individuals (instances), classes (concepts), attributes, and relations. Overview Common components of ontologies include: ;Individuals: instances or objects (the basic or "ground level" objects). ;Classes: sets, collections, concepts, types of objects, or kinds of things. ;Attributes: aspects, properties, features, characteristics, or parameters that objects (and classes) can have. ; Relations: ways in which classes and individuals can be related to one another. ;Function terms: complex structures formed from certain relations that can be used in place of an individual term in a statement. ;Restrictions: formally stated descriptions of what must be true in order for some assertion to be accepted as input. ;Rules: statements in the form of an if-then (antecedent-consequent) sentence that describe the logical inferences that can be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Database
Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis. They contain information from research areas including genomics, proteomics, metabolomics, microarray gene expression, and phylogenetics. Information contained in biological databases includes gene function, structure, localization (both cellular and chromosomal), clinical effects of mutations as well as similarities of biological sequences and structures. Biological databases can be classified by the kind of data they collect (see below). Broadly, there are molecular databases (for sequences, molecules, etc.), functional databases (for physiology, enzyme activities, phenotypes, ecology etc), taxonomic databases (for species and other taxonomic ranks), images and other media, or specimens (for museum collections etc.) Databases are important tools in assisting scientists to analyze and explain a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific Literature
: ''For a broader class of literature, see Academic publishing.'' Scientific literature comprises scholarly publications that report original empirical and theoretical work in the natural and social sciences. Within an academic field, scientific literature is often referred to as the literature. Academic publishing is the process of contributing the results of one's research into the literature, which often requires a peer-review process. Original scientific research published for the first time in scientific journals is called the primary literature. Patents and technical reports, for minor research results and engineering and design work (including computer software), can also be considered primary literature. Secondary sources include review articles (which summarize the findings of published studies to highlight advances and new lines of research) and books (for large projects or broad arguments, including compilations of articles). Tertiary sources might include encyc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Discovery (observation)
Discovery is the act of detecting something new, or something previously unrecognized as meaningful. With reference to sciences and academic disciplines, discovery is the observation of new phenomena, new actions, or new events and providing new reasoning to explain the knowledge gathered through such observations with previously acquired knowledge from abstract thought and everyday experiences. A discovery may sometimes be based on earlier discoveries, collaborations, or ideas. Some discoveries represent a radical breakthrough in knowledge or technology. New discoveries are acquired through various senses and are usually assimilated, merging with pre-existing knowledge and actions. Questioning is a major form of human thought and interpersonal communication, and plays a key role in discovery. Discoveries are often made due to questions. Some discoveries lead to the invention of objects, processes, or techniques. A discovery may sometimes be based on earlier discoveries, col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anni 2
Anni may refer to: * The popular name of Mohamed Nasheed (born 1967), third president of the second republic of the Maldives * Ani, Armenia * Anni Anwander, former West German slalom canoeist * Anni Dewani (1982–2010), Swedish female murder victim * Anni Domingo (born 1950s), British actress, director and writer * Anni, India, or Ani, a subdivision of Kullu district, Himachal Pradesh, India ** Anni Assembly constituency * Ani, Iran (other), places in Iran * ''Anni'' (1948 film), an Austrian-German film directed by Max Neufeld * ''Anni'' (1951 film), a Tamil film directed by K. S. Prakash Rao * ''Anni'' (TV series), a Tamil TV show written and produced by K. Balachander * Anni, a character in the puzzle game '' Baba Is You'' See also * Ani (other) * Annie (other) Annie may refer to: People and fictional characters * Annie (given name), a given name and a list of people and fictional characters with the name * Annie (actress) (born 1975), Indi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Online Mendelian Inheritance In Man
Online Mendelian Inheritance in Man (OMIM) is a continuously updated catalog of human genes and genetic disorders and traits, with a particular focus on the gene-phenotype relationship. , approximately 9,000 of the over 25,000 entries in OMIM represented phenotypes; the rest represented genes, many of which were related to known phenotypes. Versions and history OMIM is the online continuation of Dr. Victor A. McKusick's ''Mendelian Inheritance in Man'' (MIM), which was published in 12 editions between 1966 and 1998.McKusick, V. A. ''Mendelian Inheritance in Man. Catalogs of Autosomal Dominant, Autosomal Recessive and X-Linked Phenotypes.'' Baltimore, MD: Johns Hopkins University Press, 1st ed, 1996; 2nd ed, 1969; 3rd ed, 1971; 4th ed, 1975; 5th ed, 1978; 6th ed, 1983; 7th ed, 1986; 8th ed, 1988; 9th ed, 1990; 10th ed, 1992. Nearly all of the 1,486 entries in the first edition of MIM discussed phenotypes. MIM/OMIM is produced and curated at the Johns Hopkins School of Medicine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biocuration
Biocuration is the field of life sciences dedicated to organizing biomedical data, information and knowledge into structured formats, such as spreadsheets, tables and knowledge graphs. The biocuration of biomedical knowledge is made possible by the cooperative work of biocurators, software developers and bioinformaticians and is at the base of the work of biological databases. Biocuration as a profession A biocurator is a professional scientist who curates, collects, annotates, and validates information that is disseminated by biological and model organism databases. It is a new profession, with the first mentions in the scientific literature dating of 2006 in the context of the work in databases like the Immune Epitope Database and Analysis Resource. Biocurators usually are PhD-level with a mix of experiences in wet lab and computational representations of knowledge (e.g. via ontologies). The role of a biocurator encompasses quality control of primary biological research da ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Ontology
The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and gene product attributes; 2) annotate genes and gene products, and assimilate and disseminate annotation data; and 3) provide tools for easy access to all aspects of the data provided by the project, and to enable functional interpretation of experimental data using the GO, for example via enrichment analysis. GO is part of a larger classification effort, the Open Biomedical Ontologies, being one of the Initial Candidate Members of the OBO Foundry. Whereas gene nomenclature focuses on gene and gene products, the Gene Ontology focuses on the function of the genes and gene products. The GO also extends the effort by using markup language to make the data (not only of the genes and their products but also of curated attributes) machine read ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Unified Medical Language System
The Unified Medical Language System (UMLS) is a compendium of many controlled vocabularies in the biomedical sciences (created 1986). It provides a mapping structure among these vocabularies and thus allows one to translate among the various terminology systems; it may also be viewed as a comprehensive thesaurus and ontology of biomedical concepts. UMLS further provides facilities for natural language processing. It is intended to be used mainly by developers of systems in medical informatics. UMLS consists of Knowledge Sources (databases) and a set of software tools. The UMLS was designed and is maintained by the US National Library of Medicine, is updated quarterly and may be used for free. The project was initiated in 1986 by Donald A.B. Lindberg, M.D., then Director of the Library of Medicine, and directed by Betsy Humphreys. Purpose and applications The number of biomedical resources available to researchers is enormous. Often this is a problem due to the large volume o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
