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List Of Genetic Genealogy Topics
This is a list of genetic genealogy topics. Important concepts * Genetic genealogy * Genealogical DNA test * Human mitochondrial DNA haplogroups * Human Y-chromosome DNA haplogroups * Allele * Allele frequency * Electropherogram * Genetic recombination * Haplogroup * Haplotype * * (haplogroup) * Most recent common ancestor * Short tandem repeat (STR) * Single nucleotide polymorphism (SNP) * Y-STR (Y-chromosome short tandem repeat) Related fields * Archaeogenetics * Genealogy * Genetics ** Genetic fingerprinting ** DNA sequencing ** Population genetics ** Molecular genetics Patrilineal relationships * Patrilineality * XY sex-determination system * Y-chromosomal Adam * Y-chromosomal Aaron * Adam's Curse * Paternal mtDNA transmission * RecLOH Matrilineal relationships * Matrilineality * Mitochondrion * Mitochondrial DNA * Human mitochondrial genetics * Mitochondrial Eve * X chromosome Biogeography, ethnicity and migration * Human migration * Population genetics * Multiregional hy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Genealogy
Genetic genealogy is the use of genealogical DNA tests, i.e., DNA profiling and DNA testing, in combination with traditional genealogical methods, to infer genetic relationships between individuals. This application of genetics came to be used by family historians in the 21st century, as DNA tests became affordable. The tests have been promoted by amateur groups, such as surname study groups or regional genealogical groups, as well as research projects such as the Genographic Project. As of 2019, about 30 million people had been tested. As the field developed, the aims of practitioners broadened, with many seeking knowledge of their ancestry beyond the recent centuries, for which traditional pedigrees can be constructed. History The investigation of surnames in genetics can be said to go back to George Darwin, a son of Charles Darwin and Charles' first cousin Emma Darwin. In 1875, George Darwin used surnames to estimate the frequency of first-cousin marriages and calculated t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mitochondrion
A mitochondrion (; ) is an organelle found in the cells of most Eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term ''mitochondrion'' was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase coined by Philip Siekevitz in a 1957 article of the same name. Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells). A large number of unicellular organisms, such as microsporidia, parabasalids and diplomonads, have reduced or transformed their mitochondria into other structures. One eukaryote, ''Monocercomonoides'', is known to have completely lost its mitochondria, and one multicellular organism, '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Matrilineality
Matrilineality is the tracing of kinship through the female line. It may also correlate with a social system in which each person is identified with their matriline – their mother's lineage – and which can involve the inheritance of property and/or titles. A matriline is a line of descent from a female ancestor to a descendant (of either sex) in which the individuals in all intervening generations are mothersin other words, a "mother line". In a matrilineal descent system, an individual is considered to belong to the same descent group as their mother. This ancient matrilineal descent pattern is in contrast to the currently more popular pattern of patrilineal descent from which a family name is usually derived. The ''matriline'' of historical nobility was also called their enatic or uterine ancestry, corresponding to the patrilineal or "agnatic" ancestry. Early human kinship In the late 19th century, almost all prehistorians and anthropologists believed, followi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RecLOH
RecLOH is a term in genetics that is an abbreviation for " Recombinant Loss of Heterozygosity". This is a type of mutation which occurs with DNA by recombination. From a pair of equivalent ("homologous"), but slightly different (heterozygous) genes, a pair of identical genes results. In this case there is a non-reciprocal exchange of genetic code between the chromosomes, in contrast to chromosomal crossover, because genetic information is lost. For Y chromosome In genetic genealogy, the term is used particularly concerning similar seeming events in Y chromosome DNA. This type of mutation happens within one chromosome, and does not involve a reciprocal transfer. Rather, one homologous segment "writes over" the other. The mechanism is presumed to be different from RecLOH events in autosomal chromosomes, since the target is the very same chromosome instead of the homologous one. During the mutation one of these copies overwrites the other. Thus the differences between the two ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paternal MtDNA Transmission
In genetics, paternal mtDNA transmission and paternal mtDNA inheritance refer to the incidence of mitochondrial DNA (mtDNA) being passed from a father to his offspring. Paternal mtDNA inheritance is observed in a small proportion of species; in general, mtDNA is passed unchanged from a mother to her offspring, making it an example of non-Mendelian inheritance. In contrast, mtDNA transmission from both parents occurs regularly in certain bivalves. In animals Paternal mtDNA inheritance in animals varies. For example, in Mytilidae mussels, paternal mtDNA "is transmitted through the sperm and establishes itself only in the male gonad." In testing 172 sheep, "The Mitochondrial DNA from three lambs in two half-sib families were found to show paternal inheritance." An instance of paternal leakage resulted in a study on chickens. There has been evidences that paternal leakage is an integral part of mitochondrial inheritance of ''Drosophila simulans''. In humans In human mitochondria ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adam's Curse
''Adam's Curse: A Future Without Men'' (also known as ''Adam's Curse: A Story of Sex, Genetics, and the Extinction of Men'') is a 2003 book by Oxford University human genetics professor Bryan Sykes expounding his hypothesis that with the declining sperm count in men and the continual atrophy of the Y chromosome, within 5,000 generations (approximately 125,000 years) men shall become extinct. Sykes thinks one of the options for humanity's survival is unisex reproduction by females: female eggs fertilised by the nuclear X chromosomes of another female and implanted using in vitro fertilisation methods. He also introduces the possibility of moving the SRY and associated genes responsible for maleness and male fertility to another chromosome, which he refers to as "the Adonis chromosome", engendering fertile males with an XX karyotype. See also * Sex-determination system * Y-chromosomal Adam References * External links Review of ''Adam's Curse''from ''The Daily Telegraph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Y-chromosomal Aaron
Y-chromosomal Aaron is the name given to the hypothesized most recent common ancestor of the patrilineal Jewish priestly caste known as ''Kohanim'' (singular "Kohen", also spelled "Cohen"). According to the traditional understanding of the Hebrew Bible, this ancestor was Aaron, the brother of Moses. While some early genetic studies were seen as possibly supporting the traditional biblical narrative, this view was subsequently challenged with some researchers arguing that the genetic evidence "refutes the idea of a single founder for Jewish Cohanim who lived in Biblical times." However, recent studies have provided further support for the model of descent from a common ancestor who lived in the First Temple period by demonstrating that Kohanim from different Jewish communities form a "tight cluster" which is "specific to the Jewish Cohens". The original scientific research was based on the hypothesis that a majority of present-day Jewish Kohanim share a pattern of values fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Y-chromosomal Adam
In human genetics, the Y-chromosomal most recent common ancestor (Y-MRCA, informally known as Y-chromosomal Adam) is the patrilineal most recent common ancestor (MRCA) from whom all currently living humans are descended. He is the most recent male from whom all living humans are descended through an unbroken line of their male ancestors. The term Y-MRCA reflects the fact that the Y chromosomes of all currently living human males are directly derived from the Y chromosome of this remote ancestor. The analogous concept of the matrilineal most recent common ancestor is known as "Mitochondrial Eve" (mt-MRCA, named for the matrilineal transmission of mtDNA), the most recent woman from whom all living humans are descended matrilineally. As with "Mitochondrial Eve", the title of "Y-chromosomal Adam" is not permanently fixed to a single individual, but can advance over the course of human history as paternal lineages become extinct. Estimates of the time when Y-MRCA lived have also shifte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
XY Sex-determination System
The XY sex-determination system is a sex-determination system used to classify many mammals, including humans, some insects (''Drosophila''), some snakes, some fish (guppies), and some plants (''Ginkgo'' tree). In this system, the sex of an individual is determined by a pair of sex chromosomes. Females have two of the same kind of sex chromosome (XX), and are called the homogametic sex. Males have two different kinds of sex chromosomes (XY), and are called the heterogametic sex. In humans, the presence of the Y chromosome is responsible for triggering male development; in the absence of the Y chromosome, the fetus will undergo female development. There are various exceptions, such as individuals with Klinefelter syndrome (who have XXY chromosomes), Swyer syndrome (women with XY chromosomes), and XX male syndrome (men with XX chromosomes), however these exceptions are rare. In most species with XY sex determination, an organism must have at least one X chromosome in order to sur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patrilineality
Patrilineality, also known as the male line, the spear side or agnatic kinship, is a common kinship system in which an individual's family membership derives from and is recorded through their father's lineage. It generally involves the inheritance of property, rights, names, or titles by persons related through male kin. This is sometimes distinguished from cognate kinship, through the mother's lineage, also called the spindle side or the distaff side. A patriline ("father line") is a person's father, and additional ancestors, as traced only through males. Traditionally and historically people would identify the person's ethnicity with the father's heritage and ignore the maternal ancestry in the ethnic factor. In the Bible In the Bible, family and tribal membership appears to be transmitted through the father. For example, a person is considered to be a priest or Levite, if his father is a priest or Levite, and the members of all the Twelve Tribes are called Israelites because ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Genetics
Molecular genetics is a sub-field of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the structure and/or function of genes in an organism's genome using genetic screens. The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, Cell biology, cellular biology, molecular biology, biochemistry, and biotechnology. Researchers search for mutations in a gene or induce mutations in a gene to link a gene sequence to a specific phenotype. Molecular genetics is a powerful methodology for linking mutations to genetic conditions that may aid the search for treatments/cures for various genetics diseases. History For molecular genetics to develop as a discipline, several scientific discoveries were necessary. The discovery of DNA as a means to transfer the genetic code of life f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
