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List Of Aldolases
Unqualified, aldolase usually refers to the enzyme fructose-bisphosphate aldolase. Aldolase may also refer to: Proteins serving as fructose-bisphosphate aldolase * Aldolase A * Aldolase B * Aldolase C Other enzymes called "aldolases" * 17a-hydroxyprogesterone aldolase * 2-dehydro-3-deoxy-6-phosphogalactonate aldolase * 2-dehydro-3-deoxy-D-pentonate aldolase * 2-dehydro-3-deoxyglucarate aldolase * 2-dehydro-3-deoxy-L-pentonate aldolase * 2-dehydro-3-deoxy-phosphogluconate aldolase * 2-dehydropantoate aldolase * 3-deoxy-D-manno-octulosonate aldolase * 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase * 5-dehydro-2-deoxyphosphogluconate aldolase * Benzoin aldolase * Deoxyribose-phosphate aldolase * Dihydroneopterin aldolase * Dimethylaniline-N-oxide aldolase * Ketotetrose-phosphate aldolase * Lactate aldolase * L-fuculose-phosphate aldolase * Phenylserine aldolase * Rhamnulose-1-phosphate aldolase * Sphinganine-1-phosphate aldolase * Tagatose-bisphosphate aldolase * Threonine aldolas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fructose-bisphosphate Aldolase
Fructose-bisphosphate aldolase (), often just aldolase, is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1,6-bisphosphate, into the triose phosphates dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P). Aldolase can also produce DHAP from other (3S,4R)-ketose 1-phosphates such as fructose 1-phosphate and sedoheptulose 1,7-bisphosphate. Gluconeogenesis and the Calvin cycle, which are anabolic pathways, use the reverse reaction. Glycolysis, a catabolic pathway, uses the forward reaction. Aldolase is divided into two classes by mechanism. The word aldolase also refers, more generally, to an enzyme that performs an aldol reaction (creating an aldol) or its reverse (cleaving an aldol), such as Sialic acid aldolase, which forms sialic acid. See the list of aldolases. Mechanism and structure Class I proteins form a protonated Schiff base intermediate linking a highly conserved active site lysine with the DHAP carbonyl carbon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzoin Aldolase
The enzyme benzoin aldolase () catalyzes the chemical reaction :2-hydroxy-1,2-diphenylethanoneAlso known as benzoin. \rightleftharpoons 2 benzaldehyde This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)—the systematic name of benzoin is 2-hydroxy-1,2-diphenylethanone. Other names in common use include benzaldehyde lyase, and 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase. It employs one cofactor, thiamin diphosphate. Structural studies As of late 2007, 3 structures A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as ... have been solved for this class of enzymes, with PDB accession codes , , and . Re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Threonine Aldolase
The enzyme threonine aldolase () is an enzyme that catalyzes the chemical reaction :L-threonine \rightleftharpoons glycine + acetaldehyde This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-threonine acetaldehyde-lyase (glycine-forming). This enzyme is also called L-threonine acetaldehyde-lyase. This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, pyridoxal phosphate. Structural studies As of late 2007, 5 structures A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as ... have been solved for this class of enzymes, with Protein Data Bank, PDB accession codes , , , , and . Presence in human and mouse The enzyme is synthesized and functi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tagatose-bisphosphate Aldolase
The enzyme tagatose-bisphosphate aldolase () catalysis, catalyzes the chemical reaction :D-tagatose 1,6-bisphosphate \rightleftharpoons glycerone phosphateCommonly known as dihydroxyacetone phosphate. + Dglyceraldehyde 3-phosphate This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The List of enzymes, systematic name of this enzyme class is D-tagatose 1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming). This enzyme is also called D-tagatose-1,6-bisphosphate triosephosphate lyase. This enzyme participates in galactose metabolism. Structural studies As of late 2007, only one tertiary structure, structure has been solved for this class of enzymes, with the Protein Data Bank, PDB accession code . References * * EC 4.1.2 Enzymes of known structure {{4.1-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sphinganine-1-phosphate Aldolase
The enzyme sphinganine-1-phosphate aldolase () catalyzes the chemical reaction :sphinganine 1-phosphate \rightleftharpoons phosphoethanolamine + palmitaldehyde This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming). Other names in common use include dihydrosphingosine 1-phosphate aldolase, sphinganine-1-phosphate alkanal-lyase, sphinganine-1-phosphate lyase, and sphinganine-1-phosphate palmitaldehyde-lyase. This enzyme participates in sphingolipid metabolism. It employs one cofactor, pyridoxal phosphate Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions. The International Union of Biochemistry and Molecular Biology has catalogued more than 140 PLP-dependent ac .... References * EC 4.1.2 Pyridoxal phosphat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rhamnulose-1-phosphate Aldolase
The enzyme rhamnulose-1-phosphate aldolase () catalyzes the chemical reaction :L-rhamnulose 1-phosphate \rightleftharpoons glycerone phosphateGlycerone phosphate is often known as dihydroxyacetone phosphate. + (''S'')-lactaldehyde This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-rhamnulose-1-phosphate (S)-lactaldehyde-lyase (glycerone-phosphate-forming). Other names in common use include rhamnulose phosphate aldolase, L-rhamnulose 1-phosphate aldolase, L-rhamnulose-phosphate aldolase, and L-rhamnulose-1-phosphate lactaldehyde-lyase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism Mannose is a sugar monomer of the aldohexose series of carbohydrates. It is a C-2 epimer of glucose. Mannose is important in human metabolism, especially in the glycosylation of certain proteins. Several congenital disorders of glyc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenylserine Aldolase
The enzyme phenylserine aldolase () catalyzes the chemical reaction :L-''threo''-3-phenylserine \rightleftharpoons glycine + benzaldehyde This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming). This enzyme is also called L-threo-3-phenylserine benzaldehyde-lyase. It employs one cofactor, pyridoxal phosphate. Structural studies As of late 2007, only one structure A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as ... has been solved for this class of enzymes, with the PDB accession code . References * EC 4.1.2 Pyridoxal phosphate enzymes Enzymes of known structure {{4.1-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
L-fuculose-phosphate Aldolase
The enzyme L-fuculose-phosphate aldolase () catalysis, catalyzes the chemical reaction : L-fuculose-1-phosphate \rightleftharpoons glycerone phosphateGlycerone phosphate is often known as dihydroxyacetone phosphate. + (''S'')-lactaldehyde This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The List of enzymes, systematic name of this enzyme class is L-fuculose-1-phosphate (S)-lactaldehyde-lyase (glycerone-phosphate-forming). Other names in common use include L-fuculose 1-phosphate aldolase, fuculose aldolase, and L-fuculose-1-phosphate lactaldehyde-lyase. This enzyme participates in Fructose metabolism, fructose and mannose metabolism. Structural studies As of late 2007, 20 tertiary structure, structures have been solved for this class of enzymes, with Protein Data Bank, PDB accession codes , , , , , , , , , , , , , , , , , , , and . See also * Fuculose * L-Fuculose kinase, L-Fuculose kinase References * * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lactate Aldolase
The enzyme lactate aldolase () catalyzes the chemical reaction :(''S'')-lactate \rightleftharpoons formate + acetaldehyde This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-lactate acetaldehyde-lyase (formate-forming). Other names in common use include lactate synthase, and (S)-lactate acetaldehyde-lyase. This enzyme participates in pyruvate metabolism Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base A conjugate acid, within the Brønsted–Lowry acid–base theory, is a chemical compoun .... References * EC 4.1.2 Enzymes of unknown structure {{4.1-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ketotetrose-phosphate Aldolase
The enzyme ketotetrose-phosphate aldolase () catalyzes the chemical reaction :erythrulose 1-phosphate \rightleftharpoons glycerone phosphate + formaldehyde Hence, this enzyme has one substrate, erythrulose 1-phosphate, and two products, dihydroxyacetone phosphate and formaldehyde. This enzyme belongs to the family of lyase In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. ...s, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming). Other names in common use include phosphoketotetrose aldolase, erythrulose-1-phosphate synthetase, erythrose-1-phosphate synthase, and erythrulose-1-phosphate formaldehyde-lyase. References * EC 4.1.2 Enzymes of u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dimethylaniline-N-oxide Aldolase
The enzyme dimethylaniline-''N''-oxide aldolase () catalyzes the chemical reaction :''N,N''-dimethylaniline ''N''-oxide \rightleftharpoons ''N''-methylaniline + formaldehyde This enzyme belongs to the family of lyase In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. ...s, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming). Other names in common use include microsomal oxidase II, microsomal N-oxide dealkylase, and N,N-dimethylaniline-N-oxide formaldehyde-lyase. References * EC 4.1.2 Enzymes of unknown structure {{4.1-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dihydroneopterin Aldolase
The enzyme dihydroneopterin aldolase () catalyzes the chemical reaction :2-amino-4-hydroxy-6-(D-''erythro''-1,2,3-trihydroxypropyl)-7,8- dihydropteridine \rightleftharpoons 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropt eridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming). Other names in common use include 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-, and dihydropteridine glycolaldehyde-lyase. This enzyme participates in folate biosynthesis Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as a dietary supplement and in food fortification as it is more stable during proce ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |