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Levon Khachigian
Levon Michael Khachigian (born 6 March 1964 in Beirut, Lebanon) is an Australian medical research scientist notable for his work in vascular cell and molecular biology. He is a Professor in the Faculty of Medicine at the University of New South Wales. Khachigian is known for his studies in the area of transcriptional control and for translating basic discoveries into potential novel therapeutics. He is the inventor of the experimental drug Dz13, which may help treat a range of common diseases or complications including skin cancer, post-angioplasty restenosis, macular degeneration and asthma. Early life and education Khachigian was born to Armenian parents who served as evangelical protestant missionaries in the Middle East and migrated to Australia at age 18 months. He was raised in Naremburn, New South Wales, Australia and attended Naremburn Public School and later Crows Nest Boys' High School. Khachigian obtained a B.Sc. with first-class honours in biochemistry in 1986 and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beirut
Beirut, french: Beyrouth is the capital and largest city of Lebanon. , Greater Beirut has a population of 2.5 million, which makes it the third-largest city in the Levant region. The city is situated on a peninsula at the midpoint of Lebanon's Mediterranean coast. Beirut has been inhabited for more than 5,000 years, and was one of Phoenicia's most prominent city states, making it one of the oldest cities in the world (see Berytus). The first historical mention of Beirut is found in the Amarna letters from the New Kingdom of Egypt, which date to the 14th century BC. Beirut is Lebanon's seat of government and plays a central role in the Lebanese economy, with many banks and corporations based in the city. Beirut is an important seaport for the country and region, and rated a Beta + World City by the Globalization and World Cities Research Network. Beirut was severely damaged by the Lebanese Civil War, the 2006 Lebanon War, and the 2020 massive explosion in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
St George Hospital (Sydney)
The St George Hospital and Community Health Service is a tertiary referral hospital located in Kogarah, a southern suburb of Sydney, New South Wales, Australia. It is part of the ''South East Sydney Local Health District'' and is an accredited principal teaching Hospital of the University of New South Wales. Overview As a major tertiary and teaching hospital, St George accepts patients from other parts of Sydney, NSW and beyond. It primarily serves about 250,000 residents of southern Sydney, in the St George area bounded by Botany Bay, Cooks River in the north, Georges River in the south and Salt Pan Creek in the west. Approximately 35% of the St George area's residents are from a non-English speaking background. The hospital is also the nearest provider of specialist medical services for around 200,000 residents of the Sutherland Shire. The hospital has a designated medical trauma service and is the Medical Retrieval Service Coordination Centre for NSW. The hospital's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Australian Vascular Biology Society
Australian(s) may refer to: Australia * Australia, a country * Australians, citizens of the Commonwealth of Australia ** European Australians ** Anglo-Celtic Australians, Australians descended principally from British colonists ** Aboriginal Australians, indigenous peoples of Australia as identified and defined within Australian law * Australia (continent) ** Indigenous Australians * Australian English, the dialect of the English language spoken in Australia * Australian Aboriginal languages * ''The Australian'', a newspaper * Australiana, things of Australian origins Other uses * Australian (horse), a racehorse * Australian, British Columbia, an unincorporated community in Canada See also * The Australian (other) * Australia (other) * * * Austrian (other) Austrian may refer to: * Austrians, someone from Austria or of Austrian descent ** Someone who is considered an Austrian citizen, see Austrian nationality law * Austrian German dialect * Someth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Australian Society For Medical Research
Australian(s) may refer to: Australia * Australia, a country * Australians, citizens of the Commonwealth of Australia ** European Australians ** Anglo-Celtic Australians, Australians descended principally from British colonists ** Aboriginal Australians, indigenous peoples of Australia as identified and defined within Australian law * Australia (continent) ** Indigenous Australians * Australian English, the dialect of the English language spoken in Australia * Australian Aboriginal languages * ''The Australian'', a newspaper * Australiana, things of Australian origins Other uses * Australian (horse), a racehorse * Australian, British Columbia, an unincorporated community in Canada See also * The Australian (other) * Australia (other) * * * Austrian (other) Austrian may refer to: * Austrians, someone from Austria or of Austrian descent ** Someone who is considered an Austrian citizen, see Austrian nationality law * Austrian German dialect * Someth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Society On Thrombosis And Haemostasis
The International Society on Thrombosis and Haemostasis (ISTH) is a not-for-profit global membership organization of specialists in the field of blood coagulation and its disorders, such as thrombosis and hemophilia. It was founded in 1954 as the International Committee on Thrombosis and Haemostasis (ICTH). The society was reorganized in 1969 as the ISTH. It currently represents about 5,000 members from 98 different countries. The society initiates and promotes education and outreach initiatives, research activities, scientific meetings, peer-reviewed publications, expert committees and the development of standards allowing a common language and approach to basic and clinical science all over the world. It also publishes the medical journal ''Journal of Thrombosis and Haemostasis'' and its open access counterpart, ''Research and Practice in Thrombosis and Haemostasis''. Mission statement The International Society on Thrombosis and Haemostasis (ISTH) advances the understanding, pre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brigham And Women’s Hospital
Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two founding members of Mass General Brigham, the largest healthcare provider in Massachusetts. Sunil Eappen serves as the hospital's current president. Brigham and Women's Hospital conducts the second largest (behind MGH) hospital-based research program in the world, with an annual research budget of more than $630 million. Pioneering achievements at BWH have included the world's first successful heart valve operation and the world's first solid organ transplant. In the 2020 '' U.S. News & World Report'' hospital rankings, BWH was ranked second in Massachusetts (behind MGH) and twelfth nationally. History Brigham and Women's Hospital was established with the 1980 merger of three Harvard-affiliated hospitals: Peter Bent Brigham Hospital ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fulbright Program
The Fulbright Program, including the Fulbright–Hays Program, is one of several United States Cultural Exchange Programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of the United States and other countries, through the exchange of persons, knowledge, and skills. Via the program, competitively-selected American citizens including students, scholars, teachers, professionals, scientists, and artists may receive scholarships or grants to study, conduct research, teach, or exercise their talents abroad; and citizens of other countries may qualify to do the same in the United States. The program was founded by United States Senator J. William Fulbright in 1946 and is considered to be one of the most widely recognized and prestigious scholarships in the world. The program provides approximately 8,000 grants annually – roughly 1,600 to U.S. students, 1,200 to U.S. scholars, 4,000 to foreign students, 900 to f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Health And Medical Research Council
The National Health and Medical Research Council (NHMRC) is the main statutory authority of the Australian Government responsible for medical research. It was the eighth largest research funding body in the world in 2016, and NHMRC-funded research is globally recognised for its high quality. Around 45% of all Australian medical research from 200812 was funded by the federal government, through the NHMRC. As an independent arm of the Department of Health, the NHMRC funds high quality health and medical research, builds research capability in Australia, support the translation of health and medical research into better health outcomes, and promote the ethics and integrity in research. Non-health research is funded by the Australian Research Council. Activities The National Health and Medical Research Council Act 1992' provides for NHMRC to pursue activities designed to: * raise the standard of individual and public health throughout Australia * foster the development of consi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GATA3
GATA3 is a transcription factor that in humans is encoded by the ''GATA3'' gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes. The GATA3 transcription factor is critical for the embryonic development of various tissues as well as for inflammatory and humoral immune responses and the proper functioning of the endothelium of blood vessels. GATA3 plays central role in allergy and immunity against worm infections. ''GATA3'' haploinsufficiency (i.e. loss of one or the two inherited ''GATA3'' genes) results in a congenital disorder termed the Barakat syndrome. Current clinical and laboratory research is focusing on determining the benefits of directly or indirectly blocking the action of GATA3 in inflammatory and allergic diseases such as asthma. It is also proposed to be a clinically important marker for various types of cancer, particularly those of the breast. However, the role, if any, o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
C-Jun
Transcription factor Jun is a protein that in humans is encoded by the ''JUN'' gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the JUN gene. c-jun was the first oncogenic transcription factor discovered. The proto-oncogene c-Jun is the cellular homolog of the viral oncoprotein v-jun (). The viral homolog v-jun was discovered in avian sarcoma virus 17 and was named for ''ju-nana'', the Japanese word for 17. The human JUN encodes a protein that is highly similar to the viral protein, which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. Function Regulation Both Jun and its dimerization partners in AP-1 formation are subject to regulation by diverse extr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Egr1
EGR-1 (Early growth response protein 1) also known as ZNF268 (zinc finger protein 268) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the ''EGR1'' gene. EGR-1 is a mammalian transcription factor. It was also named Krox-24, TIS8, and ZENK. It was originally discovered in mice. Function The protein encoded by this gene belongs to the EGR family of Cys2His2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 is an important transcription factor in memory formation. It has an essential role in brain neuron epigenetic reprogramming. EGR-1 recruits the TET1 p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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