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Laura L. Kiessling
Laura Lee Kiessling (born 21 September 1960) is an American chemist and the Novartis Professor of Chemistry at the Massachusetts Institute of Technology. Kiessling's research focuses on elucidating and exploiting interactions on the cell surface, especially those mediated by proteins binding to carbohydrates. Multivalent protein-carbohydrate interactions play roles in cell-cell recognition and signal transduction. Understanding and manipulating these interactions provides tools to study biological processes and design therapeutic treatments. Kiessling's interdisciplinary research combines organic synthesis, polymer chemistry, structural biology, and molecular and cell biology. Education Kiessling earned a B.S. in Chemistry from the Massachusetts Institute of Technology in 1983 and a Ph.D. in Chemistry from Yale University in 1989. At Yale, she worked with Stuart Schreiber to synthesize and study small molecules as probes of biological function. After earning her PhD, Kiessling ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lake Mills, Wisconsin
Lake Mills is a city in Jefferson County, Wisconsin, United States. The population was 6,211 at the 2020 census. The city is located partially within the Town of Lake Mills. History Lake Mills occupies the east shore of Rock Lake. The area was first settled by Captain Joseph Keyes. He called it "Lake Mills", after building a saw mill and grist mill using power from nearby Rock Lake. Lake Mills was chartered in 1836, and the first building was built in 1837. The village of Lake Mills incorporated in 1852 out of the surrounding town of Lake Mills. In 1866 the village changed its name to "Tyranena", but changed it back again to "Lake Mills" the next year. (''Tyranena'' is supposedly an indigenous name meaning "sparkling waters".) Geography Lake Mills is located at (43.080108, -88.909209). According to the United States Census Bureau, the city has a total area of , of which is land and is water. Demographics 2010 census As of the census of 2010, there were 5,708 people, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Academy Of Arts And Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other Founding Fathers of the United States. It is headquartered in Cambridge, Massachusetts. Membership in the academy is achieved through a thorough petition, review, and election process. The academy's quarterly journal, ''Dædalus'', is published by MIT Press on behalf of the academy. The academy also conducts multidisciplinary public policy research. History The Academy was established by the Massachusetts legislature on May 4, 1780, charted in order "to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people." The sixty-two incorporating fellows represented varying interests and high standing in the political, professional, and commercial secto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetrahedron Prize
The Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry is awarded annually by Elsevier, the publisher of Tetrahedron Publications. It was established in 1980 and named in honour of the founding co-chairmen of these publications, Professor Sir Robert Robinson and Professor Robert Burns Woodward. The prize consists of a gold medal, a certificate, and a monetary award of US $15,000. Prizewinners Winners of the prize are: See also * List of chemistry awards This list of chemistry awards is an index to articles about notable awards for chemistry. It includes awards by the Royal Society of Chemistry, the American Chemical Society, the Society of Chemical Industry and awards by other organizations. ... References {{reflist Awards established in 1981 British science and technology awards Chemistry awards ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MacArthur Fellows Program
The MacArthur Fellows Program, also known as the MacArthur Fellowship and commonly but unofficially known as the "Genius Grant", is a prize awarded annually by the John D. and Catherine T. MacArthur Foundation typically to between 20 and 30 individuals, working in any field, who have shown "extraordinary originality and dedication in their creative pursuits and a marked capacity for self-direction" and are citizens or residents of the United States. According to the foundation's website, "the fellowship is not a reward for past accomplishment, but rather an investment in a person's originality, insight, and potential," but it also says such potential is "based on a track record of significant accomplishments." The current prize is $800,000 paid over five years in quarterly installments. Previously it was $625,000. This figure was increased from $500,000 in 2013 with the release of a review of the MacArthur Fellows Program. Since 1981, 1,111 people have been named MacArthur Fello ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laura Kiessling Research - Glycopolymers And Cell Signaling
Laura may refer to: People * Laura (given name) * Laura, the British code name for the World War I Belgian spy Marthe Cnockaert Places Australia * Laura, Queensland, a town on the Cape York Peninsula * Laura, South Australia * Laura Bay, a bay on Eyre Peninsula ** Laura Bay, South Australia, a locality ** Laura Bay Conservation Park, a protected area * Laura River (Queensland) * Laura River (Western Australia) Canada * Laura, Saskatchewan Italy * Laura (Capaccio), a village of the municipality of Capaccio, Campania * Laura, Crespina Lorenzana, a village in Tuscany Marshall Islands * Laura, Marshall Islands, an island town in the Majuro Atoll of the Marshall Islands Poland * Laura, Silesian Voivodeship, a village in the administrative district of Gmina Toszek, within Gliwice County, Silesian Voivodeship, in southern Poland United States * Laura, Illinois * Laura, Indiana * Laura, Kentucky, a city * Laura, Missouri * Laura, Ohio, a small village Arts, media, and entertainme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunotherapy
Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as ''activation immunotherapies,'' while immunotherapies that reduce or suppress are classified as '' suppression immunotherapies''. Immunotherapy is under preliminary research for its potential to treat various forms of cancer. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural killer cells, and cytotoxic T lymphocytes work together to defend the body against cancer by targeting abnormal antigens expressed on the surface of tumor cells. Vaccine-induced immunity to COVID-19 relies mostly on an immunomodulatory T cell response. Therapies such as granulocyte colony-stimulating factor (G-CSF), interferons, imiquimod and cellular membrane fractions from bacteria are licensed for medical use. Others includin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Signaling
In biology, cell signaling (cell signalling in British English) or cell communication is the ability of a cell to receive, process, and transmit signals with its environment and with itself. Cell signaling is a fundamental property of all cellular life in prokaryotes and eukaryotes. Signals that originate from outside a cell (or extracellular signals) can be physical agents like mechanical pressure, voltage, temperature, light, or chemical signals (e.g., small molecules, peptides, or gas). Cell signaling can occur over short or long distances, and as a result can be classified as autocrine, juxtacrine, intracrine, paracrine, or endocrine. Signaling molecules can be synthesized from various biosynthetic pathways and released through passive or active transports, or even from cell damage. Receptors play a key role in cell signaling as they are able to detect chemical signals or physical stimuli. Receptors are generally proteins located on the cell surface or within the interio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycopolymer
Glycopolymer is synthetic polymer with pendant carbohydrates. Glycopolymers play an important role in many biological recognition events such as cell–cell adhesion, development of new tissues and infectious behavior of virus and bacteria. They have high potential in targeted drug delivery, tissue engineering and synthesis of bio-compatible materials. The first glycopolymer was synthesized in 1978 by free-radical polymerization. Subsequent efforts have been devoted to synthesizing glycopolymers with various structures and sizes, and the synthesis techniques have widened to controlled/living radical polymerisation, ring-opening polymerization In polymer chemistry, ring-opening polymerization (ROP) is a form of chain-growth polymerization, in which the terminus of a polymer chain attacks cyclic monomers to form a longer polymer (see figure). The reactive center can be radical, anion ..., ring-opening metathesis polymerization and post-functionalization. References {{reflis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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