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Laser Desorption Atmospheric Pressure Chemical Ionization
Ambient ionization is a form of ionization in which ions are formed in an ion source outside the mass spectrometer without sample preparation or separation. Ions can be formed by extraction into charged electrospray droplets, thermally desorbed and ionized by chemical ionization, or laser desorbed or ablated and post-ionized before they enter the mass spectrometer. Solid-liquid extraction Solid-liquid extraction based ambient ionization is based on the use of a charged spray, for example electrospray to create a liquid film on the sample surface. Molecules on the surface are extracted into the solvent. The action of the primary droplets hitting the surface produces secondary droplets that are the source of ions for the mass spectrometer. Desorption electrospray ionization (DESI) is one of the original ambient ionization sources and uses an electrospray source to create charged droplets that are directed at a solid sample. The charged droplets pick up the sample through i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ambient Ionization Diagram
Ambient or Ambiance or Ambience may refer to: Music and sound * Ambience (sound recording), also known as atmospheres or backgrounds * Ambient music, a genre of music that puts an emphasis on tone and atmosphere * ''Ambient'' (album), by Moby * ''Ambience'' (album), by the Lambrettas * Virgin Ambient series, a series of 24 albums released on the UK Virgin Records label between 1993 and 1997 *''Ambient 1–4'', a set of four albums by Brian Eno, released by Obscure Records between 1978 and 1982 Other * Ambient (computation), a process calculus * Ambient (desktop environment), a MUI-based desktop environment for MorphOS * ''Ambient'' (novel), a novel by Jack Womack * Mark Ambient (1860–1937), pen name of Harold Harley, English dramatist * ''Ambiancé'', an unreleased experimental film * MS ''Ambience'', a cruise ship See also * Ambient lighting (other) Ambient lighting may refer to: * Available light in an environment * Low-key lighting, a photographic technique usi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DART Schematic Small
Dart or DART may refer to: * Dart, the equipment in the game of darts Arts, entertainment and media * Dart (comics), an Image Comics superhero * Dart, a character from ''G.I. Joe'' * Dart, a ''Thomas & Friends'' railway engine character * Dart Feld, protagonist in the video game '' The Legend of Dragoon'' * ''Dart'' (poetry collection), a 2002 collection by British poet Alice Oswald Businesses and organizations * Dart (commercial vehicle), a former manufacturer of commercial vehicles in Iowa * Dart Container, a US cup and container manufacturer incorporated in the Cayman Islands * Dart Container Line, a shipping consortium that operated from 1969 to 1981 * Dart Drug, a former US drug-store chain * Dart Group, a British airline and industrial holding company * Dart Industries, a US drug-store group founded by Justin Whitlock Dart * Dart Music, a digital music aggregator based in Tennessee * Dart National Bank, a private bank in Michigan * Direct Action and Research Tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laser
A laser is a device that emits light through a process of optical amplification based on the stimulated emission of electromagnetic radiation. The word "laser" is an acronym for "light amplification by stimulated emission of radiation". The first laser was built in 1960 by Theodore H. Maiman at Hughes Research Laboratories, based on theoretical work by Charles Hard Townes and Arthur Leonard Schawlow. A laser differs from other sources of light in that it emits light which is ''coherent''. Spatial coherence allows a laser to be focused to a tight spot, enabling applications such as laser cutting and lithography. Spatial coherence also allows a laser beam to stay narrow over great distances (collimation), enabling applications such as laser pointers and lidar (light detection and ranging). Lasers can also have high temporal coherence, which allows them to emit light with a very narrow spectrum. Alternatively, temporal coherence can be used to produce ultrashort pulses of ligh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Corona Discharge
A corona discharge is an electrical discharge caused by the ionization of a fluid such as air surrounding a conductor carrying a high voltage. It represents a local region where the air (or other fluid) has undergone electrical breakdown and become conductive, allowing charge to continuously leak off the conductor into the air. A corona discharge occurs at locations where the strength of the electric field (potential gradient) around a conductor exceeds the dielectric strength of the air. It is often seen as a bluish glow in the air adjacent to pointed metal conductors carrying high voltages, and emits light by the same mechanism as a gas discharge lamp. In many high voltage applications, corona is an unwanted side effect. Corona discharge from high voltage electric power transmission lines constitutes an economically significant waste of energy for utilities. In high voltage equipment like cathode ray tube televisions, radio transmitters, X-ray machines, and particl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atmospheric Pressure Chemical Ionization
Atmospheric pressure chemical ionization (APCI) is an ionization method used in mass spectrometry which utilizes gas-phase ion-molecule reactions at atmospheric pressure (105 Pa), commonly coupled with high-performance liquid chromatography (HPLC). APCI is a soft ionization method similar to chemical ionization where primary ions are produced on a solvent spray. The main usage of APCI is for polar and relatively less polar thermally stable compounds with molecular weight less than 1500 Da. The application of APCI with HPLC has gained a large popularity in trace analysis detection such as steroids, pesticides and also in pharmacology for drug metabolites. Instrument structure A typical APCI source usually consists of three main parts: a sample inlet, a corona discharge needle, and an ion transfer region under intermediate pressure. In the case of the heated nebulizer inlet from an LC, as shown in the figure, the eluate flows at 0.2 to 2.0 mL/min into a pneumatic nebulizer which ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Probe Electrospray Ionization (schematic)
Probe electrospray ionization (PESI) is an electrospray-based ambient ionization technique which is coupled with mass spectrometry Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is use ... for sample analysis. Unlike traditional mass spectrometry ion sources which must be maintained in a vacuum, ambient ionization techniques permit sample ionization under ambient conditions, allowing for the high-throughput analysis of samples in their native state, often with minimal or no sample pre-treatment. The PESI ion source simply consists of a needle to which a high voltage is applied following sample pick-up, initiating electrospray directly from the solid needle. History Probe electrospray ionization is an ambient ionization mass spectrometry technique developed by Professor Kenzo Hiraoka et ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glow Discharge
A glow discharge is a plasma formed by the passage of electric current through a gas. It is often created by applying a voltage between two electrodes in a glass tube containing a low-pressure gas. When the voltage exceeds a value called the striking voltage, the gas ionization becomes self-sustaining, and the tube glows with a colored light. The color depends on the gas used. Glow discharges are used as a source of light in devices such as neon lights, fluorescent lamps, and plasma-screen televisions. Analyzing the light produced with spectroscopy can reveal information about the atomic interactions in the gas, so glow discharges are used in plasma physics and analytical chemistry. They are also used in the surface treatment technique called sputtering. Electrical conduction in gas Conduction in a gas requires charge carriers, which can be either electrons or ions. Charge carriers come from ionizing some of the gas molecules. In terms of current flow, glow discharge falls ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Excited State
In quantum mechanics, an excited state of a system (such as an atom, molecule or nucleus) is any quantum state of the system that has a higher energy than the ground state (that is, more energy than the absolute minimum). Excitation refers to an increase in energy level above a chosen starting point, usually the ground state, but sometimes an already excited state. The temperature of a group of particles is indicative of the level of excitation (with the notable exception of systems that exhibit negative temperature). The lifetime of a system in an excited state is usually short: spontaneous or induced emission of a quantum of energy (such as a photon or a phonon) usually occurs shortly after the system is promoted to the excited state, returning the system to a state with lower energy (a less excited state or the ground state). This return to a lower energy level is often loosely described as decay and is the inverse of excitation. Long-lived excited states are often called ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metastability In Molecules
In chemistry and physics, metastability denotes an intermediate Energy level, energetic state within a dynamical system other than the system's ground state, state of least energy. A ball resting in a hollow on a slope is a simple example of metastability. If the ball is only slightly pushed, it will settle back into its hollow, but a stronger push may start the ball rolling down the slope. Bowling pins show similar metastability by either merely wobbling for a moment or tipping over completely. A common example of metastability in science is isomerisation. Higher energy isomers are long lived because they are prevented from rearranging to their preferred ground state by (possibly large) barriers in the potential energy. During a metastable state of finite lifetime, all state-describing parameters reach and hold stationary values. In isolation: *the state of least energy is the only one the system will inhabit for an indefinite length of time, until more external energy is added ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecules
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and biochemistry, the distinction from ions is dropped and ''molecule'' is often used when referring to polyatomic ions. A molecule may be homonuclear, that is, it consists of atoms of one chemical element, e.g. two atoms in the oxygen molecule (O2); or it may be heteronuclear, a chemical compound composed of more than one element, e.g. water (molecule), water (two hydrogen atoms and one oxygen atom; H2O). In the kinetic theory of gases, the term ''molecule'' is often used for any gaseous particle regardless of its composition. This relaxes the requirement that a molecule contains two or more atoms, since the noble gases are individual atoms. Atoms and complexes connected by non-covalent interactions, such as hydrogen bonds or ionic bonds, are typic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atoms
Every atom is composed of a nucleus and one or more electrons bound to the nucleus. The nucleus is made of one or more protons and a number of neutrons. Only the most common variety of hydrogen has no neutrons. Every solid, liquid, gas, and plasma is composed of neutral or ionized atoms. Atoms are extremely small, typically around 100 picometers across. They are so small that accurately predicting their behavior using classical physics, as if they were tennis balls for example, is not possible due to quantum effects. More than 99.94% of an atom's mass is in the nucleus. The protons have a positive electric charge, the electrons have a negative electric charge, and the neutrons have no electric charge. If the number of protons and electrons are equal, then the atom is electrically neutral. If an atom has more or fewer electrons than protons, then it has an overall negative or positive charge, respectively – such atoms are called ions. The electrons of an atom are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
