Laboratory Response Network
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Laboratory Response Network
The Laboratory Response Network (LRN) is a collaborative effort within the US federal government involving the Association of Public Health Laboratories and the Centers for Disease Control and Prevention (CDC). Most state public health laboratories participate as reference laboratories (formerly level B/C) of the LRN. These facilities support hundreds of sentinel (formerly level A) laboratories in local hospitals throughout the United States and can provide sophisticated confirmatory diagnosis and typing of biological agents that may be used in a bioterrorist attack or other bio-agent incident. The LRN was established in 1999. Levels The LRN consists of a loose network of government labs at three levels:Cieslak, Theodore J. and George W. Christopher (2007), "Medical Management of Potential Biological Casualties: A Stepwise Approach", InDembek, Zygmunt F. (2007), ''Medical Aspects of Biological Warfare'', (Series: Textbooks of Military Medicine), Washington, DC: The Borden Institut ...
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Association Of Public Health Laboratories
The Association of Public Health Laboratories (APHL) is a membership organization in the United States representing the laboratories that protect the health and safety of the public. APHL serves as a liaison between public health laboratories and federal and international agencies. Membership consists of local, state, county, and territorial public health laboratories; public health environmental, agricultural and veterinary laboratories; and corporations and individuals with an interest in public health and laboratory science. APHL is a non-profit, 501(c)(3) organization with a history of over fifty years. History * 1899: American Public Health Association formed the Committee of Laboratories * 1921: Southern Public Health Laboratory Association (SPHLA) formed * 1927: SPHLA became State Laboratory Directors Conference and opened membership to other states * 1939: SPHLA changed its name to Conference of State and Provincial Laboratory Directors * 1951: Association of State and ...
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Molecular Typing Studies
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and biochemistry, the distinction from ions is dropped and ''molecule'' is often used when referring to polyatomic ions. A molecule may be homonuclear, that is, it consists of atoms of one chemical element, e.g. two atoms in the oxygen molecule (O2); or it may be heteronuclear, a chemical compound composed of more than one element, e.g. water (two hydrogen atoms and one oxygen atom; H2O). In the kinetic theory of gases, the term ''molecule'' is often used for any gaseous particle regardless of its composition. This relaxes the requirement that a molecule contains two or more atoms, since the noble gases are individual atoms. Atoms and complexes connected by non-covalent interactions, such as hydrogen bonds or ionic bonds, are typically not considere ...
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United States Department Of Homeland Security
The United States Department of Homeland Security (DHS) is the Federal government of the United States, U.S. United States federal executive departments, federal executive department responsible for public security, roughly comparable to the Interior minister, interior or home ministries of other countries. Its stated missions involve anti-terrorism, border security, immigration and customs, cyber security, and disaster prevention and management. It began operations in 2003, formed as a result of the Homeland Security Act of 2002, enacted in response to the September 11 attacks. With more than 240,000 employees, DHS is the third-largest Cabinet of the United States, Cabinet department, after the Departments of United States Department of Defense, Defense and United States Department of Veterans Affairs, Veterans Affairs. Homeland security policy is coordinated at the White House by the United States Homeland Security Council, Homeland Security Council. Other agencies with signi ...
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War On Terror
The war on terror, officially the Global War on Terrorism (GWOT), is an ongoing international Counterterrorism, counterterrorism military campaign initiated by the United States following the September 11 attacks. The main targets of the campaign are Militant Islamism, militant Islamist and Salafi jihadism, Salafi-Jihadist armed organisations such as Al-Qaeda, the Islamic State and their international affiliates; which are waging military insurgencies to overthrow governments of various Muslim world, Muslim countries. The "war on terror" uses War as metaphor, war as a metaphor to describe a variety of actions which fall outside the traditional definition of war taken to eliminate international terrorism. 43rd President of the United States George W. Bush first used the Slogans and terms derived from the September 11 attacks, term "war on terrorism" on 16 September 2001, and then "war on terror" a few days later in a formal speech to United States Congress, Congress. Bush indica ...
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Counterterrorism In The United States
Counterterrorism (also spelled counter-terrorism), also known as anti-terrorism, incorporates the practices, military tactics, techniques, and strategies that governments, law enforcement, business, and intelligence agencies use to combat or eliminate terrorism. Counterterrorism strategies are a government's motivation to use the instruments of national power to defeat terrorists, the organizations they maintain, and the networks they contain. If definitions of terrorism are part of a broader insurgency, counterterrorism may employ counterinsurgency measures. The United States Armed Forces uses the term foreign internal defense for programs that support other countries' attempts to suppress insurgency, lawlessness, or subversion, or to reduce the conditions under which threats to national security may develop. History The first counter-terrorism body formed was the Special Irish Branch of the Metropolitan Police, later renamed the Special Branch after it expanded its sc ...
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BioWatch
BioWatch is a United States federal government program to detect the release of pathogens into the air as part of a terrorist attack on major American cities. Reportedly operating in Philadelphia, New York City, Washington, DC, San Diego, Boston, Chicago, San Francisco, Atlanta, St. Louis, Houston, Los Angeles and 21 other cities,''The BioWatch Program: Detection of Bioterrorism''
Congressional Research Service Report No. RL 32152. November 19, 2003, retrieved October 22, 2007
the BioWatch program was created in 2001 in response to the increased threat of bioterrorism sparked by the , and was announced in

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Chimera (genetics)
A genetic chimerism or chimera ( ) is a single organism composed of cells with more than one distinct genotype. In animals, this means an individual derived from two or more zygotes, which can include possessing blood cells of different blood types, subtle variations in form (phenotype) and, if the zygotes were of differing sexes, then even the possession of both female and male sex organs. Animal chimeras are produced by the merger of two (or more) embryos. In plant chimeras, however, the distinct types of tissue may originate from the same zygote, and the difference is often due to mutation during ordinary cell division. Normally, genetic chimerism is not visible on casual inspection; however, it has been detected in the course of proving parentage. Another way that chimerism can occur in animals is by organ transplantation, giving one individual tissues that developed from a different genome. For example, transplantation of bone marrow often determines the recipient's en ...
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Genetic Recombination
Genetic recombination (also known as genetic reshuffling) is the exchange of genetic material between different organisms which leads to production of offspring with combinations of traits that differ from those found in either parent. In eukaryotes, genetic recombination during meiosis can lead to a novel set of genetic information that can be further passed on from parents to offspring. Most recombination occurs naturally and can be classified into two types: (1) ''interchromosomal'' recombination, occurring through independent assortment of alleles whose loci are on different but homologous chromosomes (random orientation of pairs of homologous chromosomes in meiosis I); & (2) ''intrachromosomal'' recombination, occurring through crossing over. During meiosis in eukaryotes, genetic recombination involves the pairing of homologous chromosomes. This may be followed by information transfer between the chromosomes. The information transfer may occur without physical exchange (a se ...
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Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation; Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications ...
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Centers For Disease Control And Prevention
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgia. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It especially focuses its attention on infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities designed to improve the health of United States citizens. The CDC also conducts research and provides information on non-infectious diseases, such as obesity and diabetes, and is a founding member of the International Association of National Public Health Institutes.
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