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LGD-4033
Ligandrol (VK5211, LGD-4033) is a novel nonsteroidal oral selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting and osteoporosis, discovered by Ligand Pharmaceuticals and under development by Viking Therapeutics. Ligandrol has been found in World Anti-Doping Agency (WADA) samples and in racehorses too. Like anabolic steroids, it can stimulate muscle growth. "SARMs have shown superior side effect profiles compared with anabolic steroids, which arguably makes them attractive for use by individuals seeking an unfair advantage over their competitors". WADA control At least since June 2015, ligandrol has been available via the internet. In that month, German scientists proposed a new test to detect its metabolites present in human urine, and suggested an expansion of the WADA regime. Misbranded as dietary supplement On 23 October 2017, a nutritional supplement company in Missouri called Infantry Labs was warned by the FDA that the distribut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Selective Androgen Receptor Modulator
Selective Androgen Receptor Modulators or SARMs are a class of androgen receptor ligands that maintain some of the desirable effects of androgens, such as preventing osteoporosis and muscle loss while reducing risks of developing prostate cancer. In the late 1990s, the first nonsteroidal SARM, an analog of bicalutamide, was discovered. They are intended to have the same kind of effects as androgenic drugs, such as anabolic-androgenic steroids, but be more selective in their action. At present, there are no SARMs which have been approved for therapeutic use by the U.S. Food and Drug Administration. Comparison to testosterone As previously mentioned, the purpose of research in relation to SARMs is to replace testosterone supplementation in disease treatment with selective androgen receptor molecules. This is due to the fact that testosterone supplementation can have adverse effects on patients, which are detailed on the testosterone page. Thinking of testosterone as a model m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shayna Jack
Shayna Jack (born 6 November 1998) is an Australian swimmer. She competed at the 2017 World Aquatics Championships, where she won two silver and two bronze medals in the relay events. From 2019 to 2021, Jack served a 24 month suspension upheld by the Court of Arbitration for Sport for an anti-doping rule violation on 26 June 2019. 2014: Double Junior Pan Pacific champion at 15 years of age At the 2014 Junior Pan Pacific Swimming Championships, held in August in Kihei, United States, 15-year-old Jack won a gold medal in the 4×100 meter freestyle relay with a Championships record time of 3:39.73, the gold medal in the 100 meter freestyle with a 54.82, the silver medal in the 200 meter freestyle with a 1:59.48, a silver medal in the 4×200 meter freestyle relay, and placed fifth in the 50 meter freestyle.Hy-Tek (31 August 2014)"2014 Jr Pan Pacific Swimming Championships: Results" ''swmeets.com''. Retrieved 24 August 2022. 2019–2021: Positive doping test, Suspension Jack pul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oral Administration
Oral administration is a route of administration where a substance is taken through the mouth. Per os abbreviated to P.O. is sometimes used as a direction for medication to be taken orally. Many medications are taken orally because they are intended to have a systemic effect, reaching different parts of the body via the bloodstream, for example. Oral administration can be easier and less painful than other routes, such as injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients willing and able to swallow. Terminology ''Per os'' (; ''P.O.'') is an adverbial phrase meaning literally from Latin "through the mouth" or "by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanozolol
Stanozolol ( abbrev. Stz), sold under many brand names, is an androgen and anabolic steroid (AAS) medication derived from dihydrotestosterone (DHT). It is used to treat hereditary angioedema. It was developed by American pharmaceutical company Winthrop Laboratories (Sterling Drug) in 1962, and has been approved by the U.S. Food and Drug Administration for human use, though it is no longer marketed in the USA. It is also used in veterinary medicine. Stanozolol has mostly been discontinued, and remains available in only a few countries. It is given by mouth in humans or by injection into muscle in animals. Unlike most injectable AAS, stanozolol is not esterified and is sold as an aqueous suspension, or in oral tablet form. The drug has a high oral bioavailability, due to a C17α alkylation which allows the hormone to survive first-pass liver metabolism when ingested. It is because of this that stanozolol is also sold in tablet form. Stanozolol is one of the AAS commonly used as p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicolás Jarry
Nicolás Jarry Fillol (; born 11 October 1995) is a professional tennis player from Chile. He has won one tournament in singles and two in doubles on the ATP Tour. He achieved his highest ATP singles ranking of World No. 38 in July 2019, after clinching his first ATP title in Båstad. His highest doubles ranking of World No. 40 was achieved in March 2019. Personal life He is the grandson of Jaime Fillol, a former ATP player who won seven titles, and the great-nephew of Álvaro Fillol. Career Junior and early career Jarry reached the final of the 2013 French Open in boys' doubles, partnering with Cristian Garín were defeated by Kyle Edmund and Frederico Ferreira Silva. Fillol ended the year no. 18 in junior rankings. Jarry was called for the Chile Davis Cup team for the first time in September 2013 in the rubber against Dominican Republic. Chile lost and was relegated to the Group II of Americas Zone. 2015–16: Pro debut, top 200 and constant injuries In February 2015 Jar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Association Of Tennis Professionals
The Association of Tennis Professionals (ATP) is the governing body of the men's professional tennis circuits – the ATP Tour, the ATP Challenger Tour and the ATP Champions Tour. It was formed in September 1972 by Donald Dell, Jack Kramer, and Cliff Drysdale to protect the interests of professional tennis players, and Drysdale became the first President. Since 1990, the association has organized the ATP Tour, the worldwide tennis tour for men and linked the title of the tour with the organization's name. It is the governing body of men's professional tennis. In 1990 the organization was called the ATP Tour, which was renamed in 2001 as just ATP and the tour being called ATP Tour. In 2009 the name of the tour was changed again and was known as the ATP World Tour, but changed again to the ATP Tour by 2019. It is an evolution of the tour competitions previously known as Grand Prix tennis tournaments and World Championship Tennis (WCT).The ATP's global headquarters are in London. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laurence Vincent-Lapointe
Laurence Vincent Lapointe (born May 27, 1992) is a Canadian sprint canoer. She has won eleven gold medals at the ICF Canoe Sprint World Championships, starting with the 2010 Poznań Championships, and most recently three gold medals at the 2018 Montemor-o-Velho Championships. She has also won a gold medal at the 2015 Pan American Games, and silver and bronze medals at the 2020 Summer Olympics in Tokyo. Career Laurence Vincent Lapointe first made her name on the international scene in 2010 when she won a pair of gold medals in the C-1 200m and C-2 500m at the ICF World Championships. She repeated those results at the 2011 and 2013 World Championships. Also in 2013, she became the first-ever U-23 world champion in the C-1 200m. In 2014, she won her fourth straight world title in the C-1 200m in world record time of 46.419 seconds. Vincent Lapointe returned to the top of the world championship podium in 2017, winning C-1 200m gold and C-2 500m gold with Katie Vincent. At the f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Australian Broadcasting Corporation
The Australian Broadcasting Corporation (ABC) is the national broadcaster of Australia. It is principally funded by direct grants from the Australian Government and is administered by a government-appointed board. The ABC is a publicly-owned body that is politically independent and fully accountable, with its charter enshrined in legislation, the ''Australian Broadcasting Corporation Act 1983''. ABC Commercial, a profit-making division of the corporation, also helps to generate funding for content provision. The ABC was established as the Australian Broadcasting Commission on 1 July 1932 by an act of federal parliament. It effectively replaced the Australian Broadcasting Company, a private company established in 1924 to provide programming for A-class radio stations. The ABC was given statutory powers that reinforced its independence from the government and enhanced its news-gathering role. Modelled after the British Broadcasting Corporation ( BBC), which is funded by a te ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Joakim Noah
Joakim Simon Noah ( ; born February 25, 1985) is an American-born French-Swedish former professional basketball player. He played college basketball for the Florida Gators, winning back-to-back NCAA championships in 2006 and 2007. The Chicago Bulls selected Noah with the ninth overall pick in the 2007 NBA draft. Noah is a two-time NBA All-Star and was named to the All-NBA First Team in 2014 when he also was named the NBA Defensive Player of the Year. He was also a member of the French national team. Early life Noah was born in New York City, to French singer and former world No. 3 tennis player Yannick Noah, winner of the French Open in 1983, and Cécilia Rodhe, Miss Sweden and fourth runner-up at Miss Universe 1978. His grandfather Zacharie Noah was a Cameroonian professional football player, winner of the Coupe de France in 1961. Noah lived in Paris, France from 1988 to 1998 and returned to New York City at age 13. He played youth basketball with the youth teams of the F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Florida
The University of Florida (Florida or UF) is a public land-grant research university in Gainesville, Florida. It is a senior member of the State University System of Florida, traces its origins to 1853, and has operated continuously on its Gainesville campus since September 1906. After the Florida state legislature's creation of performance standards in 2013, the Florida Board of Governors designated the University of Florida as a "preeminent university". For 2022, '' U.S. News & World Report'' ranked Florida as the fifth (tied) best public university and 28th (tied) best university in the United States. The University of Florida is the only member of the Association of American Universities in Florida and is classified among "R1: Doctoral Universities – Very high research activity". The university is accredited by the Southern Association of Colleges and Schools (SACS). It is the third largest Florida university by student population,Nathan Crabbe, UF is no longer l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Will Grier
William Grier (born April 3, 1995) is an American football quarterback for the Dallas Cowboys of the National Football League (NFL). He played college football at Florida and West Virginia and was drafted by the Carolina Panthers in the third round in the 2019 NFL Draft. Early years Grier attended SouthLake Christian Academy in Huntersville, North Carolina, then transferred to Davidson Day School in Davidson, North Carolina. As a junior, he threw for a national record 837 yards in a game, breaking the old record of 764. As a senior, he had 4,989 passing yards with a nation-leading and North Carolina record 77 touchdowns. He also rushed for 1,251 yards with 13 touchdowns. He was named the Parade All-American Player of the Year and Mr. Football USA. For his career, Grier had 14,565 passing yards, a state record 195 touchdown passes, 2,955 rushing yards and 31 rushing touchdowns. Grier was rated by Rivals.com as a four-star recruit and was ranked as the second best dual-threat q ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Florida Gators
The Florida Gators are the intercollegiate athletic teams that represent the University of Florida, located in Gainesville. The University of Florida, its athletic program, its alumni and its sports fans are often collectively referred to as the "Gator Nation." The Gators compete in the National Collegiate Athletic Association (NCAA) and the Southeastern Conference (SEC) and are consistently ranked among the top college sports programs in the United States. The University of Florida currently fields teams in nine men's sports and twelve women's sports. All Florida Gators sports teams compete in NCAA Division I, and 20 of the 21 Gators teams compete in the SEC. The sole University of Florida sports team that does not play in the SEC is the women's lacrosse team, which joined the American Athletic Conference beginning in the 2019 lacrosse season because the SEC does not sponsor competition in the sport. The University of Florida was one of the thirteen charter members who joined ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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