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László Detre (microbiologist)
László Detre (October 29, 1874, Nagysurány – May 7, 1939, Washington, DC (a.k.a. Ladislas Deutsch, Ladislaus Deutsch"Origins of the Terms 'Antibody' and 'Antigen'", ''Scand. J. Immunol.'', 19, 281-285, 198p. 281/ref>) was a Hungarian physician and microbiologist, the founder and first director of the Hungarian Serum Institute in Budapest. Detre coined the term "antigen" in a 1903 French-language paper co-authored with Russian biologist Élie Metchnikoff Ilya Ilyich Mechnikov (russian: Илья Ильич Мечников; – 15 July 1916), also spelled Élie Metchnikoff, was a Russian zoologist best known for his pioneering research in immunology. Belkin, a Russian science historian, explains ... (referring to "substances immunogènes ou antigènes"), although the word and concept appears in his research as early as 1899. He is also a codiscoverer of the Wassermann reaction, publishing his discovery in humans just two weeks after Wassermann documented his findings ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Washington, DC
) , image_skyline = , image_caption = Clockwise from top left: the Washington Monument and Lincoln Memorial on the National Mall, United States Capitol, Logan Circle, Jefferson Memorial, White House, Adams Morgan, National Cathedral , image_flag = Flag of the District of Columbia.svg , image_seal = Seal of the District of Columbia.svg , nickname = D.C., The District , image_map = , map_caption = Interactive map of Washington, D.C. , coordinates = , subdivision_type = Country , subdivision_name = , established_title = Residence Act , established_date = 1790 , named_for = George Washington, Christopher Columbus , established_title1 = Organized , established_date1 = 1801 , established_title2 = Consolidated , established_date2 = 1871 , established_title3 = Home Rule Ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few varia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hungarians
Hungarians, also known as Magyars ( ; hu, magyarok ), are a nation and ethnic group native to Hungary () and historical Hungarian lands who share a common culture, history, ancestry, and language. The Hungarian language belongs to the Uralic language family. There are an estimated 15 million ethnic Hungarians and their descendants worldwide, of whom 9.6 million live in today's Hungary. About 2–3 million Hungarians live in areas that were part of the Kingdom of Hungary before the Treaty of Trianon in 1920 and are now parts of Hungary's seven neighbouring countries, Slovakia, Ukraine, Romania, Serbia, Croatia, Slovenia, and Austria. Significant groups of people with Hungarian ancestry live in various other parts of the world, most of them in the United States, Canada, Germany, France, the United Kingdom, Chile, Brazil, Australia, and Argentina. Hungarians can be divided into several subgroups according to local linguistic and cultural characteristics; subgroups with distinc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbiologist
A microbiologist (from Ancient Greek, Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of Microorganism, microscopic organisms such as bacteria, algae, fungi, and some types of parasites and their vectors. Most microbiologists work in offices and/or research facilities, both in private biotechnology companies and in academia. Most microbiologists specialize in a given topic within microbiology such as bacteriology, parasitology, virology, or immunology. Duties Microbiologists generally work in some way to increase scientific knowledge or to utilise that knowledge in a way that improves outcomes in medicine or some industry. For many microbiologists, this work includes planning and conducting experimental research projects in some kind of laboratory setting. Others may have a more administrative role, supervising scientists and evaluating their results. Microbiologists working in the medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hungarian Serum Institute
Hungarian may refer to: * Hungary, a country in Central Europe * Kingdom of Hungary, state of Hungary, existing between 1000 and 1946 * Hungarians, ethnic groups in Hungary * Hungarian algorithm, a polynomial time algorithm for solving the assignment problem * Hungarian language, a Finno-Ugric language spoken in Hungary and all neighbouring countries * Hungarian notation, a naming convention in computer programming * Hungarian cuisine Hungarian or Magyar cuisine is the cuisine characteristic of the nation of Hungary and its primary ethnic group, the Magyars. Traditional Hungarian dishes are primarily based on meats, seasonal vegetables, fruits, bread, and dairy products. ..., the cuisine of Hungary and the Hungarians See also * * {{disambiguation Language and nationality disambiguation pages ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antigen
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. The term ''antigen'' originally referred to a substance that is an antibody generator. Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of monosaccharides/simple sugars), lipids, or nucleic acids. Antigens are recognized by antigen receptors, including antibodies and T-cell receptors. Diverse antigen receptors are made by cells of the immune system so that each cell has a specificity for a single antigen. Upon exposure to an antigen, only the lymphocytes that recognize that antigen are activated and expanded, a process known as clonal selection. In most cases, an antibody can only react to and bind one specific antigen; in some instances, however, antibodies may cross-react and bind more than one antigen. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Élie Metchnikoff
Ilya Ilyich Mechnikov (russian: Илья Ильич Мечников; – 15 July 1916), also spelled Élie Metchnikoff, was a Russian zoologist best known for his pioneering research in immunology. Belkin, a Russian science historian, explains why Metchnikoff himself, in his Nobel autobiography – and subsequently, many other sources – mistakenly cited his date of birth as 16 May instead of 15 May. Metchnikoff made the mistake of adding 13 days to 3 May, his Old Style birthday, as was the convention in the 20th century. But since he had been born in the 19th century, only 12 days should have been added. He and Paul Ehrlich were jointly awarded the 1908 Nobel Prize in Physiology or Medicine "in recognition of their work on immunity". Mechnikov was born in modern-day Ukraine to a Romanian noble father and a Ukrainian-Jewish mother, lived and worked for many years on the territory of what was then the Russian Empire, and later on continued his career in France. Given this com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wassermann Reaction
The Wassermann test or Wassermann reaction (WR) is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests, have mostly replaced it. Method A sample of blood or cerebrospinal fluid is taken and introduced to the antigen – cardiolipin extracted from bovine muscle or heart. Syphilis non-specific antibodies ( reagin, see RPR) react with the lipid – the Wassermann reaction of antiphospholipid antibodies (APAs). The intensity of the reaction (classed 1, 2, 3, or 4) indicates the severity of the condition. Uncertainty The reaction is not specific to syphilis and will produce a positive reaction to other diseases, including systemic lupus erythematosus, malaria, and tuberculosis. It is possible for an infected individual to produce no reaction and for a successfully treated ind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
August Paul Von Wassermann
August Paul von Wassermann (21 February 1866 – 16 March 1925) was a German bacteriologist and hygienist. Born in Bamberg, with Jewish origins, he studied at several universities throughout Germany, receiving his medical doctorate in 1888 from the University of Strassburg. In 1890 he began work under Robert Koch at the Institute for Infectious Diseases in Berlin. In 1906 he became director of the division for experimental therapy and serum research at the institute, followed by a directorship of the department of experimental therapy at the Kaiser-Wilhelm-Gesellschaft for the Advancement of Science in Berlin-Dahlem (1913).August Paul von Wassermann @ Wassermann developed a [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hungarian Microbiologists
Hungarian may refer to: * Hungary, a country in Central Europe * Kingdom of Hungary, state of Hungary, existing between 1000 and 1946 * Hungarians, ethnic groups in Hungary * Hungarian algorithm, a polynomial time algorithm for solving the assignment problem * Hungarian language, a Finno-Ugric language spoken in Hungary and all neighbouring countries * Hungarian notation, a naming convention in computer programming * Hungarian cuisine Hungarian or Magyar cuisine is the cuisine characteristic of the nation of Hungary and its primary ethnic group, the Magyars. Traditional Hungarian dishes are primarily based on meats, seasonal vegetables, fruits, bread, and dairy products. ..., the cuisine of Hungary and the Hungarians See also * * {{disambiguation Language and nationality disambiguation pages ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1874 Births
Events January–March * January 1 – New York City annexes The Bronx. * January 2 – Ignacio María González becomes head of state of the Dominican Republic for the first time. * January 3 – Third Carlist War – Battle of Caspe: Campaigning on the Ebro in Aragon for the Spanish Republican Government, Colonel Eulogio Despujol surprises a Carlist force under Manuel Marco de Bello at Caspe, northeast of Alcañiz. In a brilliant action the Carlists are routed, losing 200 prisoners and 80 horses, while Despujol is promoted to Brigadier and becomes Conde de Caspe. * January 20 – The Pangkor Treaty (also known as the Pangkor Engagement), by which the British extended their control over first the Sultanate of Perak, and later the other independent Malay States, is signed. * January 23 **Alfred, Duke of Saxe-Coburg and Gotha, Prince Alfred, Duke of Edinburgh, second son of Queen Victoria, marries Grand Duchess Maria Alexandrovna of Russia, only daug ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
