Lord Dowding Fund For Humane Research
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Lord Dowding Fund For Humane Research
The Lord Dowding Fund for Humane Research (LDF) – a department of the National Anti-Vivisection Society, the world's first anti-vivisection organisation – awards grants to scientists undertaking medical research which benefits humans, without the use of animals. Founded in 1974, the name of the Fund is in honour of the Battle of Britain's Air Chief Marshal the Lord Dowding, a past President of the National Anti-Vivisection Society. To date, the Fund has awarded grants approaching £2 million to researchers working in a wide range of research fields including microsurgery, toxicity testing of dental fillings, breast and lung cancer, product safety testing, Parkinson's disease, schizophrenia, cot deaths, cataracts, kidney research, cell culture, computer-aided drug design, biotechnology, brain damage and computer teaching packages which replace the use of animals in education of students at school and university level. LDF grant around £300,000 per year for projects which ...
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Lord Dowding
Air Chief Marshal Hugh Caswall Tremenheere Dowding, 1st Baron Dowding, (24 April 1882 – 15 February 1970) was an officer in the Royal Air Force. He was Air Officer Commanding RAF Fighter Command during the Battle of Britain and is generally credited with playing a crucial role in Britain's defence, and hence, the defeat of Adolf Hitler's plan to invade Britain. Born in Moffat, Scotland, Dowding was an officer in the British Army in the 1900s and early 1910s. He joined the Royal Flying Corps at the start of the First World War and went on to serve as a fighter pilot and then as commanding officer of No. 16 Squadron. During the inter-war years he became Air Officer Commanding Fighting Area, Air Defence of Great Britain and then joined the Air Council as Air Member for Supply and Research. In July 1936, Dowding was appointed chief of the newly created RAF Fighter Command. During the Battle of Britain in the Second World War, Dowding's Fighter Command successfully defended th ...
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London
London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a major settlement for two millennia. The City of London, its ancient core and financial centre, was founded by the Romans as '' Londinium'' and retains its medieval boundaries.See also: Independent city § National capitals The City of Westminster, to the west of the City of London, has for centuries hosted the national government and parliament. Since the 19th century, the name "London" has also referred to the metropolis around this core, historically split between the counties of Middlesex, Essex, Surrey, Kent, and Hertfordshire, which largely comprises Greater London, governed by the Greater London Authority.The Greater London Authority consists of the Mayor of London and the London Assembly. The London Mayor is distinguished fr ...
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National Anti-Vivisection Society
The National Anti-Vivisection Society (NAVS) is an international not-for-profit animal protection group, based in London, working to end animal testing, and focused on the replacement of animals in research with advanced, scientific techniques. Since 2006, the NAVS has operated its international campaigns under the working name Animal Defenders International (ADI), and the two groups now work together under the ADI name. History The NAVS of the UK is the world's first anti-vivisection organisation, founded in 1875 by Frances Power Cobbe, a humanitarian who authored articles and leaflets opposing animal experiments. Many notable people of the day supported NAVS. The Society was formed on 2 December 1875 in Victoria Street, London, under the name of the Victoria Street Society. At the time there were about 300 experiments on animals each year. Public opposition to vivisection led the Government to appoint the First Royal Commission on Vivisection in July 1875; it reported its f ...
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FMRI
Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow (hemodynamic response) related to energy use by brain cells. Since the early 1990s, fMRI has come to dominate brain mapping research because it does not involve the use of injections, surgery, the ingestion of substances, or exposure to ionizing radiation. This measure is frequently corrupted by noise from various sources; hence, statistical procedures are used to extract the underlying signal. T ...
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Magnetoencephalography
Magnetoencephalography (MEG) is a functional neuroimaging technique for mapping brain activity by recording magnetic fields produced by electrical currents occurring naturally in the brain, using very sensitive magnetometers. Arrays of SQUIDs (superconducting quantum interference devices) are currently the most common magnetometer, while the SERF (spin exchange relaxation-free) magnetometer is being investigated for future machines. Applications of MEG include basic research into perceptual and cognitive brain processes, localizing regions affected by pathology before surgical removal, determining the function of various parts of the brain, and neurofeedback. This can be applied in a clinical setting to find locations of abnormalities as well as in an experimental setting to simply measure brain activity. History MEG signals were first measured by University of Illinois physicist David Cohen in 1968, before the availability of the SQUID, using a copper induction coil as the d ...
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Neurotoxicity
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system. It occurs when exposure to a substance – specifically, a neurotoxin or neurotoxicant– alters the normal activity of the nervous system in such a way as to cause permanent or reversible damage to nervous tissue. This can eventually disrupt or even kill neurons, which are cells that transmit and process signals in the brain and other parts of the nervous system. Neurotoxicity can result from organ transplants, radiation treatment, certain drug therapies, recreational drug use, and exposure to heavy metals, bites from certain species of venomous snakes, pesticides, certain industrial cleaning solvents, fuels and certain naturally occurring substances. Symptoms may appear immediately after exposure or be delayed. They may include limb weakness or numbness, loss of memory, vision, and/or ...
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Astrocytes
Astrocytes (from Ancient Greek , , "star" + , , "cavity", "cell"), also known collectively as astroglia, are characteristic star-shaped glial cells in the brain and spinal cord. They perform many functions, including biochemical control of endothelial cells that form the blood–brain barrier, provision of nutrients to the nervous tissue, maintenance of extracellular ion balance, regulation of cerebral blood flow, and a role in the repair and scarring process of the brain and spinal cord following infection and traumatic injuries. The proportion of astrocytes in the brain is not well defined; depending on the counting technique used, studies have found that the astrocyte proportion varies by region and ranges from 20% to 40% of all glia. Another study reports that astrocytes are the most numerous cell type in the brain. Astrocytes are the major source of cholesterol in the central nervous system. Apolipoprotein E transports cholesterol from astrocytes to neurons and other glial ...
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1974 Establishments In The United Kingdom
Major events in 1974 include the aftermath of the 1973 oil crisis and the resignation of United States President Richard Nixon following the Watergate scandal. In the Middle East, the aftermath of the 1973 Yom Kippur War determined politics; following Israeli Prime Minister Golda Meir's resignation in response to high Israeli casualties, she was succeeded by Yitzhak Rabin. In Europe, the invasion and occupation of northern Cyprus by Turkish troops initiated the Cyprus dispute, the Carnation Revolution took place in Portugal, and Chancellor of West Germany Willy Brandt resigned following an espionage scandal surrounding his secretary Günter Guillaume. In sports, the year was primarily dominated by the FIFA World Cup in West Germany, in which the German national team won the championship title, as well as The Rumble in the Jungle, a boxing match between Muhammad Ali and George Foreman in Zaire. Events January–February * January 26 – Bülent Ecevit of CHP forms the ne ...
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Animal Welfare Organisations Based In The United Kingdom
Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia. With few exceptions, animals consume organic material, breathe oxygen, are able to move, can reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of cells, the blastula, during embryonic development. Over 1.5 million living animal species have been described—of which around 1 million are insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a bilaterally symmetric body plan. The Bilateria include the protostomes, containing animals such as nematodes, arthropods, flatworms, annelids and molluscs, and the deuterostomes, containing the echino ...
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Anti-vivisection Organizations
Vivisection () is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for experimentation on live animalsTansey, E.MReview of ''Vivisection in Historical Perspective by Nicholaas A. Rupke, book reviews, National Center for Biotechnology Information, p. 226. by organizations opposed to animal experimentation,Yarri, Donna''The Ethics of Animal Experimentation: A Critical Analysis and Constructive Christian Proposal, Oxford University Press, 2005, p. 163. but the term is rarely used by practising scientists. Human vivisection, such as live organ harvesting, has been perpetrated as a form of torture. Animal vivisection Research requiring vivisection techniques that cannot be met through other means is often subject to an external ethics review in conception and implementation, and in many jurisdictions use of anesthesia is l ...
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