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Kristen Kroll
Kristen Kroll is an American developmental and stem cell biologist and Professor of Developmental Biology at Washington University School of Medicine. Her laboratory studies transcriptional and epigenetic regulation of brain development and its disruption to cause neurodevelopmental disorders. Early life and education Kroll grew up in Wisconsin. She graduated from Wilmot High School in 1984 and received her Bachelor's Degree with the highest honors from Northwestern University in 1988. She became interested in a career in developmental biology while doing undergraduate research in the laboratory of Robert Holmgren, where her project involved cloning the segment polarity gene Cubitus interruptus, a ''Drosophila'' homolog of the GLI transcription factors that mediate Hedgehog signaling. Career In her doctoral work in John Gerhart's lab at the University of California at Berkeley, Kroll developed nuclear transplantation-based approaches for transgenesis in embryos of the frog ''Xen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of Regeneration (biology), regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryogenesis, embryonic development of animals are: tissue patterning (via regional specification and patterned cellular differentiation, cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
