Krebiozen
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Krebiozen
Krebiozen (aka Carcalon, creatine, substance X, or drug X) is a disproven cancer treatment that is made available as an alternative cancer treatment. While the substance has been marketed as a cure for cancer, originally sold for thousands of dollars per dose in the 1950s and early '60s, Krebiozen is not known to possess any therapeutic value. Attempts to analyze its composition have shown that Krebiozen consists only of the amino acid creatine dissolved in mineral oil, and some samples sold as Krebiozen consist solely of mineral oil with no other discernible ingredients. The American Cancer Society states: "Available scientific evidence does not support claims that Krebiozen is effective in treating cancer or any other disease." According to the U.S. Food and Drug Administration (FDA), Krebiozen has been linked to several dangerous side effects. History and evaluation Krebiozen was initially promoted by Stevan Durovic, a Yugoslavian physician who claimed that the substance c ...
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List Of Unproven And Disproven Cancer Treatments
This is a non-exhaustive list of alternative treatments that have been promoted to treat or prevent cancer in humans but which lack scientific and medical evidence of effectiveness. In many cases, there is scientific evidence that the alleged treatments are not effective, and in some cases, may even be harmful. Unlike accepted cancer treatments, treatments lacking in evidence of efficacy are generally ignored or avoided by the medical community and are often pseudoscientific. Alternative health systems * Aromatherapy – the use of fragrant substances, such as essential oils, in the belief that smelling them will positively affect health. There is some evidence that aromatherapy improves general well-being, but it has also been promoted for its ability to fight diseases, including cancer. The American Cancer Society states "available scientific evidence does not support claims that aromatherapy is effective in preventing or treating cancer". * Ayurvedic medicine  ...
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List Of Ineffective Cancer Treatments
This is a non-exhaustive list of alternative treatments that have been promoted to treat or prevent cancer in humans but which lack scientific and medical evidence of effectiveness. In many cases, there is scientific evidence that the alleged treatments are not effective, and in some cases, may even be harmful. Unlike accepted cancer treatments, treatments lacking in evidence of efficacy are generally ignored or avoided by the medical community and are often pseudoscientific. Alternative health systems * Aromatherapy – the use of fragrant substances, such as essential oils, in the belief that smelling them will positively affect health. There is some evidence that aromatherapy improves general well-being, but it has also been promoted for its ability to fight diseases, including cancer. The American Cancer Society states "available scientific evidence does not support claims that aromatherapy is effective in preventing or treating cancer". * Ayurvedic medicine  ...
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Andrew Conway Ivy
Andrew Conway Ivy (February 25, 1893 – February 7, 1978) was an American physician. He was appointed by the American Medical Association as its representative at the 1946 Nuremberg Medical Trial for Nazi doctors, but later fell into disrepute for advocating the fraudulent drug Krebiozen. Personal life Born in Farmington, Missouri, Ivy grew up in Cape Girardeau, Missouri. His father was a science professor and his mother was a teacher. Ivy trained in medicine and physiology in Chicago and taught at Northwestern University before becoming vice president of the University of Illinois, being responsible for the medicine, dentistry and pharmacy schools. From 1939 to 1941 he was president of the American Physiological Society. According to author Jonathan Moreno, by the end of the war he was probably ''the most famous doctor in the country''. He was author of the Green report. In 1919, he was married to Emma Anna Kohman, who had her PhD in physiology from the University of Chicago. ...
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Journal Of The American Medical Association
''The Journal of the American Medical Association'' (''JAMA'') is a peer-reviewed medical journal published 48 times a year by the American Medical Association. It publishes original research, reviews, and editorials covering all aspects of biomedicine. The journal was established in 1883 with Nathan Smith Davis as the founding editor. Kirsten Bibbins-Domingo of the University of California San Francisco became the journal editor-in-chief on July 1, 2022, succeeding Howard Bauchner of Boston University. History The journal was established in 1883 by the American Medical Association and superseded the ''Transactions of the American Medical Association''. ''Councilor's Bulletin'' was renamed the ''Bulletin of the American Medical Association'', which later was absorbed by the ''Journal of the American Medical Association''. In 1960, the journal obtained its current title, ''JAMA: The Journal of the American Medical Association''. The journal is commonly referred to as ''JAMA''. ...
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Alternative Cancer Treatments
Alternative cancer treatment describes any cancer treatment or practice that is not part of the conventional standard of cancer care. These include special diets and exercises, chemicals, herbs, devices, and manual procedures. Most alternative cancer treatments do not have high-quality evidence supporting their use. Concerns have been raised about the safety of some of them. Some have even been found to be unsafe in certain settings. Despite this, many untested and disproven treatments are used around the world. Promoting or marketing such treatments is illegal in most of the developed world. Alternative cancer treatments are typically contrasted with experimental cancer treatments – science-based treatment methods – and complementary treatments, which are non-invasive practices used in combination with conventional treatment. All approved chemotherapy medications were considered experimental treatments before completing safety and efficacy testing. Since the ...
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Homeopathy
Homeopathy or homoeopathy is a pseudoscientific system of alternative medicine. It was conceived in 1796 by the German physician Samuel Hahnemann. Its practitioners, called homeopaths, believe that a substance that causes symptoms of a disease in healthy people can cure similar symptoms in sick people; this doctrine is called '' similia similibus curentur'', or "like cures like". Homeopathic preparations are termed ''remedies'' and are made using homeopathic dilution. In this process, the selected substance is repeatedly diluted until the final product is chemically indistinguishable from the diluent. Often not even a single molecule of the original substance can be expected to remain in the product. Between each dilution homeopaths may hit and/or shake the product, claiming this makes the diluent remember the original substance after its removal. Practitioners claim that such preparations, upon oral intake, can treat or cure disease. All relevant scientific knowledge about ...
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Active Ingredient
An active ingredient is any ingredient that provides biologically active or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the body of humans or animals. The similar terms active pharmaceutical ingredient (also abbreviated as API) and bulk active are also used in medicine, and the term active substance may be used for natural products. Some medication products may contain more than one active ingredient. The traditional word for the active pharmaceutical agent is pharmacon or pharmakon (from el, φάρμακον, adapted from '' pharmacos'') which originally denoted a magical substance or drug. The terms active constituent or active principle are often chosen when referring to the active substance of interest in a plant (such as salicylic acid in willow bark or arecoline in areca nuts), because the word "ingredient" in many minds connotes a sense of human agency (that is, something t ...
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Creatine Monohydrate
Creatine ( or ) is an organic compound with the nominal formula (H2N)(HN)CN(CH3)CH2CO2H. It exists in various modifications (tautomers) in solution. Creatine is found in vertebrates where it facilitates recycling of adenosine triphosphate (ATP), primarily in muscle and brain tissue. Recycling is achieved by converting adenosine diphosphate (ADP) back to ATP via donation of phosphate groups. Creatine also acts as a buffer. History Creatine was first identified in 1832 when Michel Eugène Chevreul isolated it from the basified water-extract of skeletal muscle. He later named the crystallized precipitate after the Greek word for meat, κρέας (''kreas''). In 1928, creatine was shown to exist in equilibrium with creatinine. Studies in the 1920s showed that consumption of large amounts of creatine did not result in its excretion. This result pointed to the ability of the body to store creatine, which in turn suggested its use as a dietary supplement. In 1912, Harvard Univers ...
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Alma Levant Hayden
Alma Levant Hayden (March 27, 1927 – August 2, 1967) was an American chemist, and one of the first African-American women to gain a scientist position at a science agency in Washington, D.C. She joined the National Institutes of Health (NIH) in the 1950s. Hayden graduated from Howard University with a master's degree in chemistry, and became an expert in spectrophotometry, the measurement of how substances absorb light. She published work on infrared and other techniques for analyzing chemicals in a range of journals. Hayden was appointed Chief of the Spectrophotometer Research Branch in the Division of Pharmaceutical Chemistry at the U.S. Food and Drug Administration (FDA) in 1963, and may have been the first African-American scientist at the FDA. Hayden came to national attention in 1963 when she led the team that exposed the common substance in Krebiozen, a long-controversial alternative and expensive drug promoted as anti-cancer. Education Alma Levant was born in Greenville ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ...
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National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship. NCI is the oldest and has the largest budget and research program of the 27 institutes and centers of the NIH ($6.9 billion in 2020). It fulfills the majority of its mission via an extramural program that provides grants for cancer research. Additionally, the National Cancer Institute has intramural research programs in Bethesda, Maryland, and at the Frederick National Laboratory for Cancer Research at Fort Detrick in Frederick, Maryland. The NCI receives more than in funding each ...
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Time (magazine)
''Time'' (stylized in all caps) is an American news magazine based in New York City. For nearly a century, it was published Weekly newspaper, weekly, but starting in March 2020 it transitioned to every other week. It was first published in New York City on March 3, 1923, and for many years it was run by its influential co-founder, Henry Luce. A European edition (''Time Europe'', formerly known as ''Time Atlantic'') is published in London and also covers the Middle East, Africa, and, since 2003, Latin America. An Asian edition (''Time Asia'') is based in Hong Kong. The South Pacific edition, which covers Australia, New Zealand, and the Pacific Islands, is based in Sydney. Since 2018, ''Time'' has been published by Time USA, LLC, owned by Marc Benioff, who acquired it from Meredith Corporation. History ''Time'' has been based in New York City since its first issue published on March 3, 1923, by Briton Hadden and Henry Luce. It was the first weekly news magazine in the United St ...
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