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Kitasato Shibasaburō
Baron was a Japanese physician and bacteriologist. He is remembered as the co-discoverer of the infectious agent of bubonic plague in Hong Kong during an outbreak in 1894, almost simultaneously with Alexandre Yersin. Kitasato was nominated for the first annual Nobel Prize in Physiology or Medicine in 1901. Kitasato and Emil von Behring, working together in Berlin in 1890, announced the discovery of diphtheria antitoxin serum. Von Behring was awarded the 1901 Nobel Prize because of this work, but Kitasato was not. Biography Kitasato was born in Okuni village, Higo Province, (present-day Oguni Town, Kumamoto Prefecture, Kyūshū), the son of Kitasato Korenobu, a village head, and Tei, the daughter of a samurai. His parents were strict about his education and sent him to a relative's home and requested rigid discipline. He is said to have inherited his leadership qualities from his mother. He was educated at Kumamoto Medical School and Tokyo Imperial University. He studied ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oguni, Kumamoto
is a town in Aso District, Kumamoto Prefecture, Japan. As of 2003, the town had an estimated population of 8,735 and a density of 63.76 persons per km². The total area is 137.00 km². Sightseeing *Kitasato Shibasaburō Baron was a Japanese physician and bacteriologist. He is remembered as the co-discoverer of the infectious agent of bubonic plague in Hong Kong during an outbreak in 1894, almost simultaneously with Alexandre Yersin. Kitasato was nominated ... Memorial Museum: Oguni is Kitasato's birthplace. * Tsuetate Onsen (杖立温泉) * Nuruyu Onsen (奴留湯温泉) * Nabegataki Falls (鍋ケ滝) *Sakamoto Zenzo Museum of Art References External links *Oguni official website Towns in Kumamoto Prefecture {{Kumamoto-geo-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diphtheria
Diphtheria is an infection caused by the bacterium '' Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild clinical course, but in some outbreaks more than 10% of those diagnosed with the disease may die. Signs and symptoms may vary from mild to severe and usually start two to five days after exposure. Symptoms often come on fairly gradually, beginning with a sore throat and fever. In severe cases, a grey or white patch develops in the throat. This can block the airway and create a barking cough as in croup. The neck may swell in part due to enlarged lymph nodes. A form of diphtheria which involves the skin, eyes or genitals also exists. Complications may include myocarditis, inflammation of nerves, kidney problems, and bleeding problems due to low levels of platelets. Myocarditis may result in an abnormal heart rate and inflammation of the nerves may result in paralysis. Diphtheria is usually spread between people by direct contact or through th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fukuzawa Yukichi
was a Japanese educator, philosopher, writer, entrepreneur and samurai who founded Keio University, the newspaper '' Jiji-Shinpō'', and the Institute for Study of Infectious Diseases. Fukuzawa was an early advocate for reform in Japan. His ideas about the organization of government and the structure of social institutions made a lasting impression on a rapidly changing Japan during the Meiji period. He appears on the current 10,000- Japanese yen banknote. Early life Fukuzawa Yukichi was born into an impoverished low-ranking samurai (military nobility) family of the Okudaira Clan of Nakatsu Domain (present-day Ōita, Kyushu) in 1835. His family lived in Osaka, the main trading center for Japan at the time. His family was poor following the early death of his father, who was also a Confucian scholar. At the age of 5 he started Han learning, and by the time he turned 14, he had studied major writings such as the '' Analects'', ''Tao Te Ching'', '' Zuo Zhuan'' and ''Zhuang ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Passive Immunity
Passive immunity is the transfer of active humoral immunity of ready-made antibodies. Passive immunity can occur naturally, when maternal antibodies are transferred to the fetus through the placenta, and it can also be induced artificially, when high levels of antibodies specific to a pathogen or toxin (obtained from humans, horses, or other animals) are transferred to non-immune persons through blood products that contain antibodies, such as in immunoglobulin therapy or antiserum therapy. Passive immunization is used when there is a high risk of infection and insufficient time for the body to develop its own immune response, or to reduce the symptoms of ongoing or immunosuppressive diseases.Microbiology and Immunology On-Line Textbook : USC School of Medicine Passive immunization can be provided when ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthrax Disease
Anthrax is an infection caused by the bacterium '' Bacillus anthracis''. It can occur in four forms: skin, lungs, intestinal, and injection. Symptom onset occurs between one day and more than two months after the infection is contracted. The skin form presents with a small blister with surrounding swelling that often turns into a painless ulcer with a black center. The inhalation form presents with fever, chest pain and shortness of breath. The intestinal form presents with diarrhea (which may contain blood), abdominal pains, nausea and vomiting. The injection form presents with fever and an abscess at the site of drug injection. According to the USA's Centers for Disease Control and Prevention, the first clinical descriptions of cutaneous anthrax were given by Maret in 1752 and Fournier in 1769. Before that anthrax had been described only through historical accounts. The Prussian scientist Robert Koch (1843–1910) was the first to identify ''Bacillus anthracis'' as the bacte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emil Adolf Von Behring
Emil von Behring (; Emil Adolf von Behring), born Emil Adolf Behring (15 March 1854 – 31 March 1917), was a German physiologist who received the 1901 Nobel Prize in Physiology or Medicine, the first one awarded in that field, for his discovery of a diphtheria antitoxin. He was widely known as a "saviour of children," as diphtheria used to be a major cause of child death. His work with the disease, as well as tetanus, has come to bring him most of his fame and acknowledgment. He was honored with Prussian nobility in 1901, henceforth being known by the surname "von Behring." Biography Behring was born in Hansdorf, Kreis Rosenberg, Province of Prussia (now Ławice, Iława County, Poland). His father was a schoolmaster; the family had 13 children. Between 1874 and 1878, he studied medicine at the Kaiser-Wilhelm-Akademie in Berlin, an academy for military doctors, since his family could not afford the university. As a military doctor, he studied the action of iodoform. Due to his wo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Culture
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions the need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases ( CO2, O2), and regulates the physio-chemical environment (pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetanus
Tetanus, also known as lockjaw, is a bacterial infection caused by ''Clostridium tetani'', and is characterized by muscle spasms. In the most common type, the spasms begin in the jaw and then progress to the rest of the body. Each spasm usually lasts a few minutes. Spasms occur frequently for three to four weeks. Some spasms may be severe enough to fracture bones. Other symptoms of tetanus may include fever, sweating, headache, trouble swallowing, high blood pressure, and a fast heart rate. Onset of symptoms is typically three to twenty-one days following infection. Recovery may take months. About ten percent of cases prove to be fatal. ''C. tetani'' is commonly found in soil, saliva, dust, and manure. The bacteria generally enter through a break in the skin such as a cut or puncture wound by a contaminated object. They produce toxins that interfere with normal muscle contractions. Diagnosis is based on the presenting signs and symptoms. The disease does not spread between pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Humboldt University Of Berlin
Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative of Wilhelm von Humboldt, Johann Gottlieb Fichte and Friedrich Ernst Daniel Schleiermacher as the University of Berlin () in 1809, and opened in 1810, making it the oldest of Berlin's four universities. From 1828 until its closure in 1945, it was named Friedrich Wilhelm University (german: Friedrich-Wilhelms-Universität). During the Cold War, the university found itself in East Berlin and was ''de facto'' split in two when the Free University of Berlin opened in West Berlin. The university received its current name in honour of Alexander and Wilhelm von Humboldt in 1949. The university is divided into nine faculties including its medical school shared with the Freie Universität Berlin. The university has a student enrollment of around 32 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Samurai
were the hereditary military nobility and officer caste of medieval and early-modern Japan from the late 12th century until their abolition in 1876. They were the well-paid retainers of the '' daimyo'' (the great feudal landholders). They had high prestige and special privileges such as wearing two swords and ''Kiri-sute gomen'' (right to kill anyone of a lower class in certain situations). They cultivated the '' bushido'' codes of martial virtues, indifference to pain, and unflinching loyalty, engaging in many local battles. Though they had predecessors in earlier military and administrative officers, the samurai truly emerged during the Kamakura shogunate, ruling from 1185 to 1333. They became the ruling political class, with significant power but also significant responsibility. During the 13th century, the samurai proved themselves as adept warriors against the invading Mongols. During the peaceful Edo period (1603 to 1868), they became the stewards and chamberlains of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanushi
''Nanushi'' (Japanese: 名主) was a village official in the Edo period. They were village headmen, administering a village (''mura'') under a district magistrate (''gun-dai''), the ''daikan'' of a district governor (''gunji''). Their duties included tax collection and serving as the most local administrator of a rural village in direct contact with the villagers. The term ''nanushi'' was used in Kantō, while a village head was called ''shōya'' (庄屋) in Kansai and ''kimoiri'' (肝煎) in Tōhoku and Hokuriku. Overview The duties of ''nanushi'' included tax collection, general village administration, management of public natural resources (such as mountain, field, river and ocean) of the village called ''iriai'', as well as negotiating with the territorial lord as the representative of the villagers. The post was typically monopolized by one or more powerful peasant families, the ''gōnō'', through hereditary succession, though nominally appointed by the territorial lord ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kyūshū
is the third-largest island of Japan's five main islands and the most southerly of the four largest islands ( i.e. excluding Okinawa). In the past, it has been known as , and . The historical regional name referred to Kyushu and its surrounding islands. Kyushu has a land area of and a population of 14,311,224 in 2018. In the 8th-century Taihō Code reforms, Dazaifu was established as a special administrative term for the region. Geography The island is mountainous, and Japan's most active volcano, Mount Aso at , is on Kyushu. There are many other signs of tectonic activity, including numerous areas of hot springs. The most famous of these are in Beppu, on the east shore, and around Mt. Aso in central Kyushu. The island is separated from Honshu by the Kanmon Straits. Being the nearest island to the Asian continent, historically it is the gateway to Japan. The total area is which makes it the 37th largest island in the world. It's slightly larger than Taiwan island . ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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