Kinetoplastids
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Kinetoplastids
Kinetoplastida (or Kinetoplastea, as a class) is a group of flagellated protists belonging to the phylum Euglenozoa, and characterised by the presence of an organelle with a large massed DNA called kinetoplast (hence the name). The organisms are commonly referred to as "kinetoplastids" or "kinetoplasts" The group includes a number of parasites responsible for serious diseases in humans and other animals, as well as various forms found in soil and aquatic environments. Their distinguishing feature, the presence of a kinetoplast, is an unusual DNA-containing granule located within the single mitochondrion associated with the base of the cell's flagellum (the basal body). The kinetoplast contains many copies of the mitochondrial genome. The kinetoplastids were first defined by Bronislaw M. Honigberg in 1963 as the members of the flagellated protozoans. They are traditionally divided into the biflagellate Bodonidae and uniflagellate Trypanosomatidae; the former appears to be paraphyle ...
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Bodonida
Bodonida is an order of kinetoplastid flagellate excavates. It contains the genera ''Bodo'' and '' Rhynchomonas'', relatives to the parasitic trypanosomes. This order also contains the colonial genus '' Cephalothamnium''. Taxonomy Bodonida contains the following suborders and families: * Eubodonina * Neobodonina ** Bodonidae Bütschli, 1887 ** Neobodonidae ** Rhynchomonadidae * Parabodonina ** Cryptobiidae Vickerman ** Parabodonidae Cavalier-Smith Thomas (Tom) Cavalier-Smith, FRS, FRSC, NERC Professorial Fellow (21 October 1942 – 19 March 2021), was a professor of evolutionary biology in the Department of Zoology, at the University of Oxford. His research has led to discov ... References Kinetoplastids Excavata orders {{Excavata-stub ...
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Bodo (excavate)
''Bodo'' () is a genus of microscopic kinetoplastids, flagellate excavates first described in 1831 by Christian Gottfried Ehrenberg.Ehrenberg C.G. 1831. Über die Entwicklung und Lebensdauer der Infusionsthiere nebst ferneren Beiträgen zu einer Vergleichung ihrer organischen Systemen. Physikalische Abhandlungen der Königlichen Akademie der Wissenschaften zu Berlin 1-154. The genus is small, as it has recently been redefined to include only four species.Cavalier-Smith, T. 2016. Higher classification and phylogeny of Euglenozoa. European Journal of Protistology 56, 250–276. ''Bodo'' includes free-living, phagotrophic organisms that can be found in many marine and freshwater environments as well as some terrestrial environments. Being phagotrophic, ''Bodo'' feeds on bacteria and other microorganisms that it finds while swimming through its water-based habitats. The swimming-like movement is facilitated by the two unequal flagella that ''Bodo'' possesses which arise from an ante ...
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Cryptobia
''Cryptobia'' is a genus of kinetoplastids. Several species are known for being fish pathogens. They can be found in other animals, as well. The name ''Trypanoplasma'' is occasionally used for some of these.Woo, P. T. K. (2003)''Cryptobia'' (''Trypanoplasma'') ''salmositica'' and salmonid cryptobiosis.''Journal of Fish Diseases'' 26(11-12) 627–46. Biology There are 52 species of ''Cryptobia'' known from fish. 40 of these live in the blood, 7 in the gut, and 5 on the body surface. Examples include: *''Cryptobia branchialis'', an ectoparasite that lives on the skin or gills. It can deform the skin and cause anorexia and death. *''Cryptobia iubilans'', an endoparasite that lives in the intestines and causes granulomatous inflammation of the abdominal organs, resulting in weight loss and death. *''Cryptobia salmositica'', '' C. borreli'', and '' C. bullocki'', blood parasites that lead to anaemia and lesions in the haematopoietic tissues. Some ''Cryptobia'' parasitize other animal ...
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Bodo (genus)
''Bodo'' () is a genus of microscopic kinetoplastids, flagellate excavates first described in 1831 by Christian Gottfried Ehrenberg.Ehrenberg C.G. 1831. Über die Entwicklung und Lebensdauer der Infusionsthiere nebst ferneren Beiträgen zu einer Vergleichung ihrer organischen Systemen. Physikalische Abhandlungen der Königlichen Akademie der Wissenschaften zu Berlin 1-154. The genus is small, as it has recently been redefined to include only four species.Cavalier-Smith, T. 2016. Higher classification and phylogeny of Euglenozoa. European Journal of Protistology 56, 250–276. ''Bodo'' includes free-living, phagotrophic organisms that can be found in many marine and freshwater environments as well as some terrestrial environments. Being phagotrophic, ''Bodo'' feeds on bacteria and other microorganisms that it finds while swimming through its water-based habitats. The swimming-like movement is facilitated by the two unequal flagella that ''Bodo'' possesses which arise from an ante ...
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Kinetoplast
A kinetoplast is a network of circular DNA (called kDNA) inside a large mitochondrion that contains many copies of the mitochondrial genome. The most common kinetoplast structure is a disk, but they have been observed in other arrangements. Kinetoplasts are only found in Excavata of the class Kinetoplastida. The variation in the structures of kinetoplasts may reflect phylogenic relationships between kinetoplastids. A kinetoplast is usually adjacent to the organism's flagellar basal body, suggesting that it is tightly bound to the cytoskeleton. In '' Trypanosoma brucei'' this cytoskeletal connection is called the tripartite attachment complex and includes the protein p166. ''Trypanosoma'' In trypanosomes, a group of flagellated protozoans, the kinetoplast exists as a dense granule of DNA within the large mitochondrion. '' Trypanosoma brucei'', the parasite which causes African trypanosomiasis (African sleeping sickness), is an example of a trypanosome with a kinetoplast. Its ki ...
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Lynn Margulis
Lynn Margulis (born Lynn Petra Alexander; March 5, 1938 – November 22, 2011) was an American evolutionary biologist, and was the primary modern proponent for the significance of symbiosis in evolution. Historian Jan Sapp has said that "Lynn Margulis's name is as synonymous with symbiosis as Charles Darwin's is with evolution." In particular, Margulis transformed and fundamentally framed current understanding of the evolution of cells with nuclei – an event Ernst Mayr called "perhaps the most important and dramatic event in the history of life" – by proposing it to have been the result of symbiotic mergers of bacteria. Margulis was also the co-developer of the Gaia hypothesis with the British chemist James Lovelock, proposing that the Earth functions as a single self-regulating system, and was the principal defender and promulgator of the five kingdom classification of Robert Whittaker. Throughout her career, Margulis' work could arouse intense objection (one grant applic ...
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Leishmania
''Leishmania'' is a parasitic protozoan, a single-celled organism of the genus '' Leishmania'' that are responsible for the disease leishmaniasis. They are spread by sandflies of the genus ''Phlebotomus'' in the Old World, and of the genus ''Lutzomyia'' in the New World. At least 93 sandfly species are proven or probable vectors worldwide.WHO (2010) Annual report. Geneva Their primary hosts are vertebrates; ''Leishmania'' commonly infects hyraxes, canids, rodents, and humans. History Members of an ancient genus of the ''Leishmania'' parasite, ''Paleoleishmania'', have been detected in fossilized sand flies dating back to the early Cretaceous period. The first written reference to the conspicuous symptoms of cutaneous leishmaniasis surfaced in the Paleotropics within oriental texts dating back to the 7th century BC (allegedly transcribed from sources several hundred years older, between 1500 and 2000 BC). Due to its broad and persistent prevalence throughout antiquity as a mys ...
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