Keith E. Mostov
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Keith E. Mostov
Keith E. Mostov is an American cell biologist. He received a BA from University of Chicago in 1976 and during 1976–77 he was a Rhodes Scholar at New College, Oxford. Mostov received a PhD in Biological Science from the Rockefeller University in the laboratory of Nobel laureate Günter Blobel in 1983, and an MD from Weill Cornell Medicine in 1984. He was a Whitehead Fellow at the Whitehead Institute of MIT from 1984 to 1989. In 1989, Mostov joined the faculty of the University of California, San Francisco, School of Medicine, where he is currently Professor. Mostov and colleagues discovered and sequenced the Polymeric Immunoglobulin Receptor (pIgR) and proposed the generally accepted model of its pathway and function. Neil E. Simister and Mostov cloned and sequenced the Neonatal Fc Receptor (FcRn The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the ''FCGRT'' gene. It is an IgG Fc recepto ...
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University Of Chicago
The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the best universities in the world and it is among the most selective in the United States. The university is composed of an undergraduate college and five graduate research divisions, which contain all of the university's graduate programs and interdisciplinary committees. Chicago has eight professional schools: the Law School, the Booth School of Business, the Pritzker School of Medicine, the Crown Family School of Social Work, Policy, and Practice, the Harris School of Public Policy, the Divinity School, the Graham School of Continuing Liberal and Professional Studies, and the Pritzker School of Molecular Engineering. The university has additional campuses and centers in London, Paris, Beijing, Delhi, and Hong Kong, as well as in downtown ...
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Madin-Darby Canine Kidney Cells
Madin-Darby canine kidney (MDCK) cells are a model mammalian cell line used in biomedical research. MDCK cells are used for a wide variety of cell biology studies including cell polarity, cell-cell adhesions (termed adherens junctions), collective cell motility, toxicity studies, as well as responses to growth factors. It is one of few cell culture models that is suited for 3D cell culture and multicellular rearrangements known as branching morphogenesis. History Following the initial isolation in 1958 of epithelial cells from the kidney tubule of an adult Cocker Spaniel dog by Stewart H. Madin and Norman B. Darby, Jr., the cell line bearing their name was employed primarily as a model for viral infection of mammalian cells. Indeed, they chose to isolate kidney tubules with precisely this goal in mind, as they had previously succeeded with viral infection of cells derived from kidney tubules from other mammals. Thus the initial goal in isolating and culturing cells from this tiss ...
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21st-century American Biologists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ...
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Cell Biologists
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such a ...
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UCSF School Of Medicine Faculty
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences. UCSF was founded as Toland Medical College in 1864. in 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at Parnassus Heights with satellite facilities throughout the city, UCSF developed a second major campus in the newly redeveloped Mission Bay district in the early 2000s. '' U.S. New ...
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University Of Chicago Alumni
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ...
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Weill Cornell Medical College Alumni
Weill is an educational institution affiliated with Cornell University, named after Sanford I. Weill and may refer to: * Weill Institute for Cell and Molecular Biology, research institute located on Cornell University's Ithaca, NY campus * Weill Medical College of Cornell University, medical school located in New York City * Weill Cornell Graduate School of Medical Sciences, graduate college for biomedical sciences located in New York City * Weill Medical College in Qatar, medical school located in Qatar See also * Weil (other) * Weil (surname) Weil, Weill, and Weyl are related German and German-Jewish surnames. Notable bearers of the surnames include: Weil * Adolf Weil (physician) (or Adolph Weill) (1848–1916), German physician * Adolf Weil (motorcyclist) (1938–2011), German mot ...
, also listing people with the surname "Weill" {{disambig ...
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Rockefeller University Alumni
Rockefeller is a German surname, originally given to people from the village of Rockenfeld near Neuwied in the Rhineland and commonly referring to subjects associated with the Rockefeller family. It may refer to: People with the name Rockefeller family *John D. Rockefeller Sr. (1839–1937), founder of the Standard Oil Company *Laura Spelman Rockefeller (1839–1915), wife of John D.R., namesake of Spelman College *William Rockefeller (1841–1922), brother of John D.R. * Bessie Rockefeller Strong (1866–1906), daughter of John D.R. * Alice Rockefeller (1869–1870), daughter of John D.R. * Alta Rockefeller Prentice (1871–1962), daughter of John D.R., founder Alta House (settlement house) *Edith Rockefeller McCormick (1872–1932), daughter of John D.R., feminist, philanthropist *John D. Rockefeller Jr. (Junior) (1874–1960), son of Senior *Abby Aldrich Rockefeller (1874–1948), wife of Junior *Percy Avery Rockefeller (1878–1934), son of William * Margaret Rockefeller Strong ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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1956 Births
Events January * January 1 – The Anglo-Egyptian Sudan, Anglo-Egyptian Condominium ends in Sudan. * January 8 – Operation Auca: Five U.S. evangelical Christian Missionary, missionaries, Nate Saint, Roger Youderian, Ed McCully, Jim Elliot and Pete Fleming, are killed for trespassing by the Huaorani people of Ecuador, shortly after making contact with them. * January 16 – Egyptian leader Gamal Abdel Nasser vows to reconquer Palestine (region), Palestine. * January 25–January 26, 26 – Finnish troops reoccupy Porkkala, after Soviet Union, Soviet troops vacate its military base. Civilians can return February 4. * January 26 – The 1956 Winter Olympics open in Cortina d'Ampezzo, Italy. February * February 11 – British Espionage, spies Guy Burgess and Donald Maclean (spy), Donald Maclean resurface in the Soviet Union, after being missing for 5 years. * February 14–February 25, 25 – The 20th Congress of the Communist Party of the Soviet Union is held in Mosc ...
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FcRn
The neonatal Fc receptor (also FcRn, IgG receptor FcRn large subunit p51, or Brambell receptor) is a protein that in humans is encoded by the ''FCGRT'' gene. It is an IgG Fc receptor which is similar in structure to the MHC class I molecule and also associates with beta-2-microglobulin. In rodents, FcRn was originally identified as the receptor that transports maternal immunoglobulin G (IgG) from mother to neonatal offspring via mother's milk, leading to its name as the neonatal Fc receptor. In humans, FcRn is present in the placenta where it transports mother's IgG to the growing fetus. FcRn has also been shown to play a role in regulating IgG and serum albumin turnover. Neonatal Fc receptor expression is up-regulated by the proinflammatory cytokine, TNF-α, and down-regulated by IFN-γ. Interactions of FcRn with IgG and serum albumin In addition to binding to IgG, FCGRT has been shown to interact with human serum albumin. FcRn-mediated transcytosis of IgG across epithelial ...
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