Kareem Mohamed Abu-Elmagd
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Kareem Mohamed Abu-Elmagd
Kareem Abu-Elmagd (born June 16, 1952) is an Egyptian-American surgeon practicing abdominal organ transplantation and digestive system surgery. He is best known for development of clinical intestinal and multivisceral transplantation and its subsequent approval by Medicare (United States), Medicare. He served as the president of the Intestinal Transplant Association. Biography Abu-Elmagd was born in Mansoura, the capital of Dakahlia Governorate in 1952. In 1976 he obtained his medical degree at Mansoura University School of Medicine. In 1987 earned his PhD in liver diseases and portal hypertensive surgery through a joint collaboration between Emory University in Atlanta and Mansoura University. In 1989, he joined the University of Pittsburgh to obtain clinical fellowship in transplantation surgery. In 2001, he was promoted to professor of surgery at the University of Pittsburgh. In 1989, he was introduced to the field of organ transplantation by the late professor Thomas Star ...
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Mansoura, Egypt
Mansoura (' , rural: ) is a city in Egypt, with a population of 960,423. It is the capital of the Dakahlia Governorate. Etymology ''Mansoura'' in Arabic means "victorious". The city is named after the El Mansoura Battle against Louis IX of France during the Seventh Crusade. History Mansoura was established in 1219 by al-Kamil of the Ayyubid dynasty upon a Phatmetic branch of the Nile on a place of several older villages like Al-Bishtamir () and Kafr al-Badamas (, from , "river,canal"). After the Egyptians defeated the Crusaders during the Seventh Crusade, it was named ''Mansoura'' (aka. "The Victorious"). In the Seventh Crusade, the Capetians were defeated and put to flight; between fifteen and thirty thousand of their men fell on the battlefield. Louis IX of France was captured in the main Battle of Fariskur, and confined in the house of Ibrahim Ibn Lokman, secretary of the sultan, and under the guard of the eunuch Sobih. The king's brother was imprisoned in the same ho ...
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Mansoura
Mansoura (' , rural: ) is a city in Egypt, with a population of 960,423. It is the capital of the Dakahlia Governorate. Etymology ''Mansoura'' in Arabic means "victorious". The city is named after the El Mansoura Battle against Louis IX of France during the Seventh Crusade. History Mansoura was established in 1219 by al-Kamil of the Ayyubid dynasty upon a Phatmetic branch of the Nile on a place of several older villages like Al-Bishtamir () and Kafr al-Badamas (, from , "river,canal"). After the Egyptians defeated the Crusaders during the Seventh Crusade, it was named ''Mansoura'' (aka. "The Victorious"). In the Seventh Crusade, the Capetians were defeated and put to flight; between fifteen and thirty thousand of their men fell on the battlefield. Louis IX of France was captured in the main Battle of Fariskur, and confined in the house of Ibrahim Ibn Lokman, secretary of the sultan, and under the guard of the eunuch Sobih. The king's brother was imprisoned in the same ...
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Atlanta
Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 living within the city limits, it is the eighth most populous city in the Southeast and 38th most populous city in the United States according to the 2020 U.S. census. It is the core of the much larger Atlanta metropolitan area, which is home to more than 6.1 million people, making it the eighth-largest metropolitan area in the United States. Situated among the foothills of the Appalachian Mountains at an elevation of just over above sea level, it features unique topography that includes rolling hills, lush greenery, and the most dense urban tree coverage of any major city in the United States. Atlanta was originally founded as the terminus of a major state-sponsored railroad, but it soon became the convergence point among several rai ...
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1952 Births
Year 195 ( CXCV) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Scrapula and Clemens (or, less frequently, year 948 ''Ab urbe condita''). The denomination 195 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus has the Roman Senate deify the previous emperor Commodus, in an attempt to gain favor with the family of Marcus Aurelius. * King Vologases V and other eastern princes support the claims of Pescennius Niger. The Roman province of Mesopotamia rises in revolt with Parthian support. Severus marches to Mesopotamia to battle the Parthians. * The Roman province of Syria is divided and the role of Antioch is diminished. The Romans annexed the Syrian cities of Edessa and Nisibis. Severus re-establish his h ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Parenteral Nutrition
Parenteral nutrition (PN) is the feeding of nutritional products to a person intravenously, bypassing the usual process of eating and digestion. The products are made by pharmaceutical compounding companies. The person receives a nutritional mix according to a formula including glucose, salts, amino acids, lipids and vitamins and dietary minerals. It is called total parenteral nutrition (TPN) or total nutrient admixture (TNA) when no significant nutrition is obtained by other routes, and partial parenteral nutrition (PPN) when nutrition is also partially enteric. It is called peripheral parenteral nutrition (PPN) when administered through vein access in a limb rather than through a central vein as central venous nutrition (CVN). Medical uses Total parenteral nutrition (TPN) is provided when the gastrointestinal tract is nonfunctional because of an interruption in its continuity (it is blocked, or has a leak – a fistula) or because its absorptive capacity is impaired.Kozier, ...
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Ladd's Procedure
Ladd's bands, sometimes called bands of Ladd, are fibrous stalks of peritoneal tissue that attach the cecum to the retroperitoneum in the right lower quadrant (RLQ). Obstructing Ladd's Bands are associated with malrotation of the intestine, a developmental disorder in which the cecum is found in the right upper quadrant (RUQ), instead of its normal anatomical position in the RLQ. Ladd's bands then pass over the second part of the duodenum, causing extrinsic compression and obstruction. This clinically manifests as poor feeding and bilious vomiting in neonates. Screening can be performed with an upper GI series. The most severe complication of malrotation is midgut volvulus, in which the mesenteric base twists around the superior mesenteric artery, compromising intestinal perfusion, leading to bowel necrosis. A surgical operation called a "Ladd procedure" is performed to alleviate intestinal malrotation. The procedure involves counterclockwise detorsion of the bowel, surgical div ...
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Intestinal Malrotation
Intestinal malrotation is a congenital anomaly of rotation of the midgut. It occurs during the first trimester as the fetal gut undergoes a complex series of growth and development. Malrotation can lead to a dangerous complication called volvulus. Malrotation can refer to a spectrum of abnormal intestinal positioning, often including: * The small intestine found predominantly on the right side of the abdomen * The cecum displaced from its usual position in the right lower quadrant into the epigastrium or right hypochondrium * An absent or displaced ligament of Treitz * Fibrous peritoneal bands called bands of Ladd running across the vertical portion of the duodenum * An unusually narrow, stalk-like mesentery The position of the intestines, narrow mesentery and Ladd's bands can contribute to several severe gastrointestinal conditions. The narrow mesentery predisposes some cases of malrotation to midgut volvulus, a twisting of the entire small bowel that can obstruct the mesenteric b ...
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Donor-specific Antibody
Donor-specific antibodies (DSA) are a concept in transplantation medicine and describe the presence of antibodies specific to the Donor's HLA-Molecules. These antibodies can cause antibody-mediated rejection and are therefore considered a contraindication against transplantation in most cases.Lionaki S, Panagiotellis K, Iniotaki A, Boletis JN. Incidence and clinical significance of de novo donor specific antibodies after kidney transplantation. Clin Dev Immunol. 2013; 2013:849835. DSA are a result of B cell and plasma cell activation and bind to HLA and/or non-HLA molecules on the endothelium of the graft. They were first described in 1969 by Patel et al., who found that Transplant recipients who were positively tested for DSA using a complement-dependent cytotoxicity crossmatch assay had a higher risk of transplant rejection.Patel R, Terasaki PI. Significance of the positive crossmatch test in kidney transplantation. N Engl J Med. 1969; 280(14):735-9. DSA can either be pre-formed ...
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Liver Transplantation
Liver transplantation or hepatic transplantation is the replacement of a diseased liver with the healthy liver from another person (allograft). Liver transplantation is a treatment option for end-stage liver disease and acute liver failure, although availability of donor organs is a major limitation. The most common technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ in the same anatomic position as the original liver. The surgical procedure is complex, requiring careful harvest of the donor organ and meticulous implantation into the recipient. Liver transplantation is highly regulated, and only performed at designated transplant medical centers by highly trained transplant physicians and supporting medical team. The duration of the surgery ranges from 4 to 18 hours depending on outcome. Favorable outcomes require careful screening for eligible recipient, as well as a well-calibrated live or cadaveric donor match. Medic ...
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Tacrolimus
Tacrolimus, sold under the brand name Prograf among others, is an immunosuppressive drug. After allogeneic organ transplant, the risk of organ rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. For example, it is prescribed for severe refractory uveitis after a bone marrow transplant, exacerbations of minimal change disease, Kimura's disease, and vitiligo. It can be used to treat dry eye syndrome in cats and dogs. Tacrolimus inhibits calcineurin, which is involved in the production of interleukin-2, a molecule that promotes the development and proliferation of T cells, as part of the body's learned (or adaptive) immune response. Chemically, it is a macrolide lactone that was first discovered in 1987, from the fermentation broth of a Japanese soil sample that contained the bacterium ''Streptomyces tsukubensis''. It is on ...
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Intestinal Transplantation
Intestine transplantation (intestinal transplantation, or small bowel transplantation) is the surgical replacement of the small intestine for chronic and acute cases of intestinal failure. While intestinal failure can oftentimes be treated with alternative therapies such as parenteral nutrition (PN), complications such as PN-associated liver disease and short bowel syndrome may make transplantation the only viable option. One of the rarest type of organ transplantation performed, intestine transplantation is becoming increasingly prevalent as a therapeutic option due to improvements in immunosuppressive regimens, surgical technique, PN, and the clinical management of pre and post-transplant patients. History Intestine transplantation dates back to 1959, when a team of surgeons at the University of Minnesota led by Richard C. Lillehei reported successful transplantation of the small intestine in dogs. Five years later in 1964, Ralph Deterling in Boston attempted the first huma ...
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