|
Histone H1
Histone H1 is one of the five main histone protein families which are components of chromatin in eukaryotic cells. Though highly conserved, it is nevertheless the most variable histone in sequence across species. Structure Metazoan H1 proteins feature a central globular "winged helix" domain and long C- and short N-terminal tails. H1 is involved with the packing of the "beads on a string" sub-structures into a high order structure, whose details have not yet been solved. H1 found in protists and bacteria, otherwise known as nucleoproteins HC1 and HC2 (, ), lack the central domain and the N-terminal tail. H1 is less conserved than core histones. The globular domain is the most conserved part of H1. Function Unlike the other histones, H1 does not make up the nucleosome "bead". Instead, it sits on top of the structure, keeping in place the DNA that has wrapped around the nucleosome. H1 is present in half the amount of the other four histones, which contribute two molecules ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hummer H1
The Hummer H1 is a four-wheel-drive utility vehicle based on the M998 Humvee, which was developed by AM General when it was a subsidiary of American Motors Corporation (AMC). Originally designed strictly for military use, the off-road vehicle was released to the civilian market. The vehicle was produced from 1992 through 2006 and was the first of what became the Hummer line. AM General built both the H1 and the Humvee in its Mishawaka, Indiana facility. GM stopped marketing the H1 in 2006 model year, but AM General continued production of the military Humvee versions through 2018. History Released for the civilian market on March 14, 1992, the Hummer built by AM General was known from photographs published during Operation Desert Storm as well as from its promotion by actor Arnold Schwarzenegger. Under a 1999 deal, General Motors bought marketing rights to the Hummer name, began marketing Hummer-branded vehicles designed by GM, and rebadged the original version built by AM Gener ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
H1 (particle Detector)
H1 was a particle detector operated at the HERA (''Hadron Elektron Ring Anlage'') collider at the German national laboratory DESY in Hamburg. The first studies for the H1 experiment were proposed in 1981. The H1 detector began operating together with HERA in 1992 and took data until 2007. It consisted of several different detector components, measured about 12 x 15 x 10 meters and weighed 2,800 tons. It was one of four detectors along the HERA accelerator. The main physics goals of the H1 experiment were the investigation of the internal structure of the proton through measurements of deep inelastic scattering, the measurements of further cross sections to study fundamental interactions between particles in order to test the Standard Model of particle physics, as well as the search for new kinds of matter and unexpected phenomena in particle physics. Scientists continue to publish scientific papers based on data taken by the H1 experiment until today, and the detailed knowledge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
H1 (Armenian Public TV)
H1, H-1, H01, H I may refer to: Places *Interstate H-1, a highway in Hawaii * Area H1, the area of Hebron controlled by the Palestinian Authority under the Hebron Protocol Science * H1 (particle detector) * Histamine H1 receptor * Histone H1, a protein * British NVC community H1, a heath zone * Hydrogen atom (H1) * Protium (isotope), an isotope of hydrogen * H I region, a cloud in the interstellar medium * ATC code H01 ''Pituitary and hypothalamic hormones and analogues'', a subgroup of the Anatomical Therapeutic Chemical Classification System * Haplogroup H1 (other), a grouping in genetics based on certain similarities * Alternative hypothesis (H1) Technology * , level 1 heading markup for HTML Web pages; see HTML element * DSC-H1, a Sony Cybershot digital camera * H1, John Harrison's first marine chronometer * Tianwen-1 (formerly ''Huoxing-1''), first Chinese space probe to reach Mars * H-1NF, the Australian Plasma Fusion Research Facility, formerly H-1 Heliac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haval H1
The Haval H1 or formerly the Great Wall Haval M4 is a Subcompact crossover, subcompact Sport utility vehicle, SUV produced by the Chinese manufacturer Great Wall Motors, Great Wall. It was essentially a rebadged and lifted Great Wall Florid, until the second generation which is a rebadged Great Wall Voleex C20R. The Great Wall Haval M4 was renamed to simply Haval H1 after Great Wall Motors, Great Wall launched Haval (marque), Haval into an individual sub-brand in 2013. First generation Based on the Great Wall Florid & Toyota Ist, the Great Wall Haval M4 has been launched on the Chinese car market in 2012. Price ranges from 63,900 to 71,900 yuan. Malaysia The Great Wall Haval M4 was launched in Malaysia in July 2014 as the Great Wall M4 with three variants available: Standard, Comfort and Premium. All three variants could be had with either a manual or automatic gearbox. Early models were fully imported from China. Local assembly in Malaysia started in December 2014. The local ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histamine H1 Receptor
The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors. This receptor is activated by the biogenic amine histamine. It is expressed in smooth muscles, on vascular endothelial cells, in the heart, and in the central nervous system. The H1 receptor is linked to an intracellular G-protein (Gq) that activates phospholipase C and the inositol triphosphate (IP3) signalling pathway. Antihistamines, which act on this receptor, are used as anti-allergy drugs. The crystal structure of the receptor has been determined (shown on the right/below) and used to discover new histamine H1 receptor ligands in structure-based virtual screening studies. Function The expression of NF-κB, the transcription factor that regulates inflammatory processes, is promoted by the constitutive activity of the H1 receptor as well as by agonists that bind at the receptor. H1-antihistamines have been shown to attenuate NF-κB expression and mitigate certain in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kawasaki H1 Mach III
The Kawasaki H1 Mach III was a two-stroke 500 cc sport bike made by Kawasaki from 1969 through to 1975. History By mid-1960s, the US had become the largest motorcycle market. American riders were demanding bikes with more horsepower and higher maximum speeds. Kawasaki already had the largest-displacement Japanese machine with their 650 cc four-stroke W series, but it did not fit the niche Kawasaki was aiming for. Honda had introduced its Honda CB450 in 1965 and in 1969, the Suzuki T500 Titan/Cobra appeared. Also in development was the Yamaha XS 650. Already familiar with the Honda CB450, Kawasaki development began work on the top secret N100 Plan in 1967. The goal was to produce a motorcycle with 500 cc displacement that was able to develop 60 hp and have 13-second quarter-mile times, then considered over the achievable limit for a road bike. When announced, the H1 was critiqued in UK motorcycling press for their "own ambitious claim" of "the fastest and b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
H1 Lamp
The H1 is a halogen lamp designed for use in automotive headlamps and fog and driving lamps. It has also been widely applied in emergency vehicle lights. Origin The H1 was the first halogen lamp approved for automotive use. It was introduced in 1962 by a group of European bulb and headlamp manufacturers. The bulb was not approved for use in the US until 1997. Specifications Base The H1 lamp uses a P14.5s base in accord with IEC 60061. This is a round metal prefocus base 14.5 mm in diameter with a flat and two dimples so the H1 can be installed in a lamp only in the one correct orientation. There is one 6.35 mm male spade terminal in the center of the base, through which power is supplied. The H1 grounds through the metal base itself. Power and output Under ECE Regulation 37, which governs automotive filament lamps in most of the world, the H1 lamp's nominal rating is 55 W at 12 V, and its test rating is 68 W (maximum) and 1550 ± 15% lumens at 13.2 V. R37 also contains provis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hughes H-1 Racer
The Hughes H-1 Racer is a racing aircraft built by Hughes Aircraft in 1935. It set a world airspeed record and a transcontinental speed record across the United States. The H-1 Racer was the last aircraft built by a private individual to set the world speed record; most aircraft to hold the record since have been military designs. Development During his work on his movie '' Hell's Angels'', Howard Hughes employed Glenn Odekirk to maintain the fleet of over 100 aircraft used in the production. The two men shared a common interest in aviation and hatched a plan to build a record-beating aircraft. The aircraft was given many names, but is commonly known as the H-1. It was the first aircraft model produced by the Hughes Aircraft company. Design studies began in 1934 with an exacting scale model (over two feet in length) that was tested in the California Institute of Technology wind tunnel, revealing a speed potential of . Design Streamlining was a paramount design criterion resul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kawasaki H1R
The Kawasaki H1R was racing motorcycle manufactured by Kawasaki which competed in the 500 cc class of Grand Prix motorcycle racing. Based on the Kawasaki H1 street motorcycle, it was powered by a two stroke, three cylinder engine set across the frame. It was the first multi-cylinder two stroke racing motorcycle to be sold commercially to privateer racing teams. In 1970, Ginger Molloy finished second to Giacomo Agostini on the dominant MV Agusta in the 500 cc world championship. Molloy scored 4 second places during the season as Kawasaki finished second in the constructors championship. In 1971, Dave Simmonds rode the HR1 to victory at the season ending Spanish Grand Prix at Jarama Jarama () is a river in central Spain. It flows north to south, and passes east of Madrid where the El Atazar Dam is built on a tributary, the Lozoya River. It flows into the river Tagus in Aranjuez. The Manzanares is a tributary of the Jaram ... when Agostini sat out the race after ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tiger 1
The Tiger I () was a German heavy tank of World War II that operated beginning in 1942 in Africa and in the Soviet Union, usually in independent heavy tank battalions. It gave the German Army its first armoured fighting vehicle that mounted the 8.8 cm KwK 36 gun (derived from the 8.8 cm Flak 36). 1,347 were built between August 1942 and August 1944. After August 1944, production of the Tiger I was phased out in favour of the Tiger II. While the Tiger I has been called an outstanding design for its time, it has also been called overengineered, using expensive materials and labour-intensive production methods. In the early period Tiger was prone to certain types of track failures and breakdowns and was in general limited in range by its high fuel consumption. It was expensive to maintain, but generally mechanically reliable. It was difficult to transport and vulnerable to immobilisation when mud, ice, and snow froze between its overlapping and interleaved ''Schachtel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Harrison
John Harrison ( – 24 March 1776) was a self-educated English Carpentry, carpenter and clockmaker who invented the marine chronometer, a long-sought-after device for solving the History of longitude, problem of calculating longitude while at sea. Harrison's solution revolutionized navigation and greatly increased the safety of long-distance sea travel. The problem he solved was considered so important following the Scilly naval disaster of 1707 that the Parliament of Great Britain, British Parliament offered financial rewards of up to £20,000 (equivalent to £ in ) under the 1714 Longitude Act. In 1730, Harrison presented his first design, and worked over many years on improved designs, making several advances in time-keeping technology, finally turning to what were called sea watches. Harrison gained support from the Board of Longitude, Longitude Board in building and testing his designs. Toward the end of his life, he received recognition and a reward from Parliament. Harri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.jpg "Click for more on -> Tiger 1")
