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KE Family
The KE family is a medical name designated for a British family, about half of whom exhibit a severe speech disorder called developmental verbal dyspraxia. It is the first family with speech disorder to be investigated using genetic analyses, by which the speech impairment is discovered to be due to genetic mutation, and from which the gene ''FOXP2'', often dubbed the "language gene", was discovered. Their condition is also the first human speech and language disorder known to exhibit strict Mendelian inheritance. Brought to medical attention from their school children in the late 1980s, the case of KE family was taken up at the UCL Institute of Child Health in London in 1990. Initial report suggested that the family was affected by a genetic disorder. Canadian linguist Myrna Gopnik suggested that the disorder was characterized primarily by grammatical deficiency, supporting the controversial notion of a "grammar gene". Geneticists at the University of Oxford determined that the co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British People
British people or Britons, also known colloquially as Brits, are the citizens of the United Kingdom of Great Britain and Northern Ireland, the British Overseas Territories, and the Crown dependencies.: British nationality law governs modern British citizenship and nationality, which can be acquired, for instance, by descent from British nationals. When used in a historical context, "British" or "Britons" can refer to the Ancient Britons, the indigenous inhabitants of Great Britain and Brittany, whose surviving members are the modern Welsh people, Cornish people, and Bretons. It also refers to citizens of the former British Empire, who settled in the country prior to 1973, and hold neither UK citizenship nor nationality. Though early assertions of being British date from the Late Middle Ages, the Union of the Crowns in 1603 and the creation of the Kingdom of Great Britain in 1707 triggered a sense of British national identity.. The notion of Britishness and a shared ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Documentary Film
A documentary film or documentary is a non-fictional motion-picture intended to "document reality, primarily for the purposes of instruction, education or maintaining a historical record". Bill Nichols has characterized the documentary in terms of "a filmmaking practice, a cinematic tradition, and mode of audience reception hat remainsa practice without clear boundaries". Early documentary films, originally called "actuality films", lasted one minute or less. Over time, documentaries have evolved to become longer in length, and to include more categories. Some examples are educational, observational and docufiction. Documentaries are very informative, and are often used within schools as a resource to teach various principles. Documentary filmmakers have a responsibility to be truthful to their vision of the world without intentionally misrepresenting a topic. Social-media platforms (such as YouTube) have provided an avenue for the growth of the documentary- film gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Montreal, Quebec
Montreal ( ; officially Montréal, ) is the second-most populous city in Canada and most populous city in the Canadian province of Quebec. Founded in 1642 as '' Ville-Marie'', or "City of Mary", it is named after Mount Royal, the triple-peaked hill around which the early city of Ville-Marie is built. The city is centred on the Island of Montreal, which obtained its name from the same origin as the city, and a few much smaller peripheral islands, the largest of which is Île Bizard. The city is east of the national capital Ottawa, and southwest of the provincial capital, Quebec City. As of 2021, the city had a population of 1,762,949, and a metropolitan population of 4,291,732, making it the second-largest city, and second-largest metropolitan area in Canada. French is the city's official language. In 2021, it was spoken at home by 59.1% of the population and 69.2% in the Montreal Census Metropolitan Area. Overall, 85.7% of the population of the city of Montreal conside ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
McGill University
McGill University (french: link=no, Université McGill) is an English-language public research university located in Montreal, Quebec Montreal ( ; officially Montréal, ) is the second-most populous city in Canada and most populous city in the Canadian province of Quebec. Founded in 1642 as '' Ville-Marie'', or "City of Mary", it is named after Mount Royal, the triple-pe ..., Canada. Founded in 1821 by royal charter granted by George IV, King George IV,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, 1801–1895.'' McGill-Queen's University Press, 1980. the university bears the name of James McGill, a Scottish merchant whose bequest in 1813 formed the university's precursor, University of McGill College (or simply, McGill College); the name was officially changed to McGill University in 1885. McGill's main campus is on the slope of Mount Royal in downtown Montreal in the borough of Ville-Marie, Montreal, Ville-Marie, with a Macdona ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autosomal Dominant
In genetics, dominance is the phenomenon of one variant (allele) of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome. The first variant is termed dominant and the second recessive. This state of having two different variants of the same gene on each chromosome is originally caused by a mutation in one of the genes, either new (''de novo'') or inherited. The terms autosomal dominant or autosomal recessive are used to describe gene variants on non-sex chromosomes (autosomes) and their associated traits, while those on sex chromosomes (allosomes) are termed X-linked dominant, X-linked recessive or Y-linked; these have an inheritance and presentation pattern that depends on the sex of both the parent and the child (see Sex linkage). Since there is only one copy of the Y chromosome, Y-linked traits cannot be dominant or recessive. Additionally, there are other forms of dominance such as incomple ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Great Ormond Street Hospital
Great Ormond Street Hospital (informally GOSH or Great Ormond Street, formerly the Hospital for Sick Children) is a children's hospital located in the Bloomsbury area of the London Borough of Camden, and a part of Great Ormond Street Hospital for Children NHS Foundation Trust. The hospital is the largest centre for child heart surgery in the UK and one of the largest centres for heart transplantation in the world. In 1962 they developed the first heart and lung bypass machine for children. With children's book author Roald Dahl, they developed an improved shunt valve for children with hydrocephalus, and non-invasive (percutaneous) heart valve replacements. They did the first UK clinical trials of the rubella vaccine, and the first bone marrow transplant and gene therapy for severe combined immunodeficiency.Breakthroughs It is closely associated with University College London (UCL) and in partnership with the UCL Great Ormond Street Institute of Child Health, which is a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Planck Institute For Psycholinguistics
The Max Planck Institute for Psycholinguistics (German: ''Max-Planck-Institut für Psycholinguistik''; Dutch: ''Max Planck Instituut voor Psycholinguïstiek'') is a research institute situated on the campus of Radboud University Nijmegen located in Nijmegen, Gelderland, the Netherlands. The institute was founded in 1980 by Pim Levelt, and is particular for being entirely dedicated to psycholinguistics, and is also one of the few institutes of the Max Planck Society to be located outside Germany. The Nijmegen-based institute currently occupies 5th position in the Ranking Web of World Research Centers among all Max Planck institutes (7th by size, 4th by visibility). It currently employs about 235 people. Research The institute specializes in language comprehension, language production, language acquisition, language and genetics, and the relation between language and cognition. Its mission is to undertake basic research into the psychological, social and biological foundations of l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Simon E
Simon may refer to: People * Simon (given name), including a list of people and fictional characters with the given name Simon * Simon (surname), including a list of people with the surname Simon * Eugène Simon, French naturalist and the genus authority ''Simon'' * Tribe of Simeon, one of the twelve tribes of Israel Places * Şimon ( hu, links=no, Simon), a village in Bran Commune, Braşov County, Romania * Șimon, a right tributary of the river Turcu in Romania Arts, entertainment, and media Films * ''Simon'' (1980 film), starring Alan Arkin * ''Simon'' (2004 film), Dutch drama directed by Eddy Terstall Games * ''Simon'' (game), a popular computer game * Simon Says, children's game Literature * ''Simon'' (Sutcliff novel), a children's historical novel written by Rosemary Sutcliff * Simon (Sand novel), an 1835 novel by George Sand * ''Simon Necronomicon'' (1977), a purported grimoire written by an unknown author, with an introduction by a man identified only as "Sim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leipzig University
Leipzig University (german: Universität Leipzig), in Leipzig in Saxony, Germany, is one of the world's oldest universities and the second-oldest university (by consecutive years of existence) in Germany. The university was founded on 2 December 1409 by Frederick I, Elector of Saxony and his brother William II, Margrave of Meissen, and originally comprised the four scholastic faculties. Since its inception, the university has engaged in teaching and research for over 600 years without interruption. Famous alumni include Gottfried Wilhelm von Leibniz, Johann Wolfgang von Goethe, Leopold von Ranke, Friedrich Nietzsche, Robert Schumann, Richard Wagner, Tycho Brahe, Georgius Agricola, Angela Merkel and ten Nobel laureates associated with the university. History Founding and development until 1900 The university was modelled on the University of Prague, from which the German-speaking faculty members withdrew to Leipzig after the Jan Hus crisis and the Decree of Kutná Hora. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Disorders
Developmental disorders comprise a group of psychiatric conditions originating in childhood that involve serious impairment in different areas. There are several ways of using this term. The most narrow concept is used in the category "Specific Disorders of Psychological Development" in the ICD-10. These disorders comprise developmental language disorder, learning disorders, motor disorders, and autism spectrum disorders. In broader definitions ADHD is included, and the term used is neurodevelopmental disorders. Yet others include antisocial behavior and schizophrenia that begins in childhood and continues through life. However, these two latter conditions are not as stable as the other developmental disorders, and there is not the same evidence of a shared genetic liability. Developmental disorders are present from early life. Most improve as the child grows older, but some entail impairments that continue throughout life. Emergence Learning disabilities are diagnosed when ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale University
Yale University is a Private university, private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the List of Colonial Colleges, third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregationalism in the United States, Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first Doctor of Philosophy, PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elena L
Elena may refer to: People * Elena (given name), including a list of people and characters with this name * Joan Ignasi Elena (born 1968), Catalan politician * Francine Elena (born 1986), British poet Geography * Elena (town), a town in Veliko Tarnovo Province, Bulgaria ** Elena Municipality * Elena (village), a village in Haskovo Province Film and television * Elena (2011 film), ''Elena'' (2011 film), a 2011 Russian film * Elena (2012 film), ''Elena'' (2012 film), a Brazilian film * Elena (TV series), ''Elena'' (TV series), a Mexican telenovela * ''Elena of Avalor'', an American TV series * ''Daniele Cortis'', a 1947 Italian film also known as ''Elena'' Music * Elena (Cavalli), ''Elena'' (Cavalli), a 1659 opera by Francesco Cavalli * Elena (Mayr), ''Elena'' (Mayr), an 1814 opera by Mayr * Elena (song), "Elena" (song), a 1979 song by The Marc Tanner Band * ''Elena'', an EP by Puerto Muerto Other * Elena (play), ''Elena'' (play), a Cebuano play by Vicente Sotto * Extra Low ENerg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
