Jürgen Brosius
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Jürgen Brosius
Jürgen Brosius (born 1948) in Saarbrücken) is a German molecular geneticist and evolutionary biologist. He was professor and director of the Institute of Experimental Pathology at the University of Münster. Some of his scientific contributions involve the first genetic sequencing of a ribosomal RNA operon, the design of plasmids for studying gene expression, expression vectors for high-level production of recombinant proteins and RNA, RNA biology, RNomics as well as the significance of retroposition for plasticity and evolution of genomes, genes and gene modules including regulatory sequences or elements. Biography Early life and education Brosius studied chemistry and pharmacy at the Goethe University of Frankfurt and in 1974 graduated and completed the Staatsexamen (state examination) in Pharmacy. Subsequently, he pursued his Ph.D. work in biochemistry and molecular biology at the Max Planck Institute for Molecular Genetics in Berlin Dahlem in which Heinz-Günter Wittmann wa ...
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Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ...
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Peptide
Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. A polypeptide is a longer, continuous, unbranched peptide chain. Hence, peptides fall under the broad chemical classes of biological polymers and oligomers, alongside nucleic acids, oligosaccharides, polysaccharides, and others. A polypeptide that contains more than approximately 50 amino acids is known as a protein. Proteins consist of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, or to another protein or other macromolecule such as DNA or RNA, or to complex macromolecular assemblies. Amino acids that have been incorporated into peptides are termed residues. A water molecule is released during formation of each amide bond.. All peptides except cyclic pep ...
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Walter Gilbert
Walter Gilbert (born March 21, 1932) is an American biochemist, physicist, molecular biology pioneer, and Nobel laureate. Education and early life Walter Gilbert was born in Boston, Massachusetts, on March 21, 1932, the son of Emma (Cohen), a child psychologist, and Richard V. Gilbert, an economist. When Gilbert was seven years old, the family moved to the Washington D.C. area so his father could work under Harry Hopkins on the New Deal brain trust. While living in Washington the family became friends with the family of I.F. Stone and Wally met Stone's oldest daughter, Celia, when they were both 8. They later married at age 21. He was educated at the Sidwell Friends School, and attended Harvard University for undergraduate and graduate studies, earning a baccalaureate in chemistry and physics in 1953 and a master's degree in physics in 1954. He studied for his doctorate at the University of Cambridge, where he earned a PhD in physics supervised by the Nobel laureate Abdus ...
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German Research Foundation
The German Research Foundation (german: Deutsche Forschungsgemeinschaft ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germany. In 2019, the DFG had a funding budget of €3.3 billion. Function The DFG supports research in science, engineering, and the humanities through a variety of grant programmes, research prizes, and by funding infrastructure. The self-governed organization is based in Bonn and financed by the German states and the federal government of Germany. As of 2017, the organization consists of approximately 100 research universities and other research institutions. The DFG endows various research prizes, including the Leibniz Prize. The Polish-German science award Copernicus Award, Copernicus is offered jointly with the Foundation for Polish Science. According to a 2017 article in ''The Guardian'', the DFG has announced it will publish its re ...
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Phylogenetics
In biology, phylogenetics (; from Greek language, Greek wikt:φυλή, φυλή/wikt:φῦλον, φῦλον [] "tribe, clan, race", and wikt:γενετικός, γενετικός [] "origin, source, birth") is the study of the evolutionary history and relationships among or within groups of organisms. These relationships are determined by Computational phylogenetics, phylogenetic inference methods that focus on observed heritable traits, such as DNA sequences, Protein, protein Amino acid, amino acid sequences, or Morphology (biology), morphology. The result of such an analysis is a phylogenetic tree—a diagram containing a hypothesis of relationships that reflects the evolutionary history of a group of organisms. The tips of a phylogenetic tree can be living taxa or fossils, and represent the "end" or the present time in an evolutionary lineage. A phylogenetic diagram can be rooted or unrooted. A rooted tree diagram indicates the hypothetical common ancestor of the tree. An un ...
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Carl Woese
Carl Richard Woese (; July 15, 1928 – December 30, 2012) was an American microbiologist and biophysicist. Woese is famous for defining the Archaea (a new domain of life) in 1977 through a pioneering phylogenetic taxonomy of 16S ribosomal RNA, a technique that has revolutionized microbiology. He also originated the RNA world hypothesis in 1967, although not by that name. Woese held the Stanley O. Ikenberry Chair and was professor of microbiology at the University of Illinois at Urbana–Champaign. Life and education Carl Woese was born in Syracuse, New York on July 15, 1928. Woese attended Deerfield Academy in Massachusetts. He received a bachelor's degree in mathematics and physics from Amherst College in 1950. During his time at Amherst, Woese took only one biology course (Biochemistry, in his senior year) and had "no scientific interest in plants and animals" until advised by William M. Fairbank, then an assistant professor of physics at Amherst, to pursue biophysics at Y ...
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University Of California, Santa Cruz
The University of California, Santa Cruz (UC Santa Cruz or UCSC) is a public university, public Land-grant university, land-grant research university in Santa Cruz, California. It is one of the ten campuses in the University of California system. Located on Monterey Bay, on the edge of the coastal community of Santa Cruz, the campus lies on of rolling, forested hills overlooking the Pacific Ocean. Founded in 1965, UC Santa Cruz began with the intention to showcase progressive, cross-disciplinary undergraduate education, innovative teaching methods and contemporary architecture. The residential college system consists of ten small colleges that were established as a variation of the Oxbridge collegiate university system. Among the Faculty is 1 Nobel Prize Laureate, 1 Breakthrough Prize in Life Sciences recipient, 12 members from the United States National Academy of Sciences, National Academy of Sciences, 28 members of the American Academy of Arts and Sciences, and 40 members o ...
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Harry F
Harry may refer to: TV shows * ''Harry'' (American TV series), a 1987 American comedy series starring Alan Arkin * ''Harry'' (British TV series), a 1993 BBC drama that ran for two seasons * ''Harry'' (talk show), a 2016 American daytime talk show hosted by Harry Connick Jr. People and fictional characters * Harry (given name), a list of people and fictional characters with the given name * Harry (surname), a list of people with the surname * Dirty Harry (musician) (born 1982), British rock singer who has also used the stage name Harry * Harry Potter (character), the main protagonist in a Harry Potter fictional series by J. K. Rowling Other uses * Harry (derogatory term), derogatory term used in Norway * ''Harry'' (album), a 1969 album by Harry Nilsson *The tunnel used in the Stalag Luft III escape ("The Great Escape") of World War II * ''Harry'' (newspaper), an underground newspaper in Baltimore, Maryland See also *Harrying (laying waste), may refer to the following historical ...
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Fogarty International Center
The John E. Fogarty International Center was founded in 1968 by US President Lyndon Johnson at the National Institutes of Health to support international medical and behavioral research and to train international researchers. History On July 1, 1968, President Lyndon Johnson issued an Executive Order establishing the John E. Fogarty International Center for Advanced Study in the Health Sciences at the National Institutes of Health (NIH) in order to support international medical and behavioral research and to train international researchers. In March 2017, the Trump Administration proposed cuts to the NIH budget, including elimination of the Fogarty Center, saving $69 million.Donald G. McNeil JrTrump Plan Eliminates a Global Sentinel Against Disease, Experts Warn New York Times, 17 March 2017, retrieved 12 July 2018 References {{authority control Fogarty International Center Medical research institutes Medicine is the science and practice of caring for a patient, ma ...
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Protein Sequencing
Protein sequencing is the practical process of determining the amino acid sequence of all or part of a protein or peptide. This may serve to identify the protein or characterize its post-translational modifications. Typically, partial sequencing of a protein provides sufficient information (one or more sequence tags) to identify it with reference to databases of protein sequences derived from the conceptual translation of genes. The two major direct methods of protein sequencing are mass spectrometry and Edman degradation using a protein sequenator (sequencer). Mass spectrometry methods are now the most widely used for protein sequencing and identification but Edman degradation remains a valuable tool for characterizing a protein's ''N''-terminus. Determining amino acid composition It is often desirable to know the unordered amino acid composition of a protein prior to attempting to find the ordered sequence, as this knowledge can be used to facilitate the discovery of errors i ...
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Nanomole
The mole, symbol mol, is the unit of amount of substance in the International System of Units (SI). The quantity amount of substance is a measure of how many elementary entities of a given substance are in an object or sample. The mole is defined as containing exactly elementary entities. Depending on what the substance is, an elementary entity may be an atom, a molecule, an ion, an ion pair, or a subatomic particle such as an electron. For example, 10 moles of water (a chemical compound) and 10 moles of mercury (a chemical element), contain equal amounts of substance and the mercury contains exactly one atom for each molecule of the water, despite the two having different volumes and different masses. The number of elementary entities in one mole is known as the Avogadro number, which is the approximate number of nucleons ( protons or neutrons) in one gram of ordinary matter. The previous definition of a mole was simply the number of elementary entities equal to that of 12 gr ...
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