José Moura Gonçalves
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José Moura Gonçalves
José Moura Gonçalves (January 5, 1914– October 18,1996), Brazilian physician, biomedical scientist, biochemist and educator, one of the pioneers of biochemistry in the country. Moura Gonçalves studied medicine in Belo Horizonte. While a student, he began to work as an assistant in the laboratory of physiological chemistry of Professor José Baeta Vianna (May 30, 1894-October 01,1967). After graduation, he accepted an invitation to work on the chemistry of proteins and enzymes at the Instituto de Biofísica da Universidade Federal do Rio de Janeiro, under noted scientist Carlos Chagas Filho. His post-doctoral work was carried out at University of Wisconsin–Madison, in the United States, where he produced what was his most important work, the isolation of a new toxic protein from the venom of rattlesnakes, which he named crotamine. Returning to Brazil in the first years of the 1950s, he was invited by Dr. Zeferino Vaz to join the new and ambitious project of a research medic ...
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Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ...
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Venom
Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved ''venom apparatus'', such as fangs or a stinger, in a process called envenomation. Venom is often distinguished from poison, which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and toxungen, which is actively transferred to the external surface of another animal via a physical delivery mechanism. Venom has evolved in terrestrial and marine environments and in a wide variety of animals: both predators and prey, and both vertebrates and invertebrates. Venoms kill through the action of at least four major classes of toxin, namely necrotoxins and cytotoxins, which kill cells; neurotoxins, which affect nervous systems; myotoxins, which damage muscles; and haemotoxins, which disrupt blood clotting. Venomous animals cause tens of thousa ...
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Members Of The Brazilian Academy Of Sciences
Member may refer to: * Military jury, referred to as "Members" in military jargon * Element (mathematics), an object that belongs to a mathematical set * In object-oriented programming, a member of a class ** Field (computer science), entries in a database ** Member variable, a variable that is associated with a specific object * Limb (anatomy), an appendage of the human or animal body ** Euphemism for penis * Structural component of a truss, connected by nodes * User (computing), a person making use of a computing service, especially on the Internet * Member (geology), a component of a geological formation * Member of parliament * The Members, a British punk rock band * Meronymy, a semantic relationship in linguistics * Church membership, belonging to a local Christian congregation, a Christian denomination and the universal Church * Member, a participant in a club or learned society A learned society (; also learned academy, scholarly society, or academic association) is an ...
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1995 Deaths
File:1995 Events Collage V2.png, From left, clockwise: O.J. Simpson is acquitted of the murders of Nicole Brown Simpson and Ronald Goldman from the year prior in "The Trial of the Century" in the United States; The Great Hanshin earthquake strikes Kobe, Japan, killing 5,000-6,000 people; The Unabomber Manifesto is published in several U.S. newspapers; Gravestones mark the victims of the Srebrenica massacre near the end of the Bosnian War; Windows 95 is launched by Microsoft for PC; The first exoplanet, 51 Pegasi b, is discovered; Space Shuttle Atlantis docks with the Space station Mir in a display of U.S.-Russian cooperation; The Alfred P. Murrah Federal Building in Oklahoma City is bombed by domestic terrorists, killing 168., 300x300px, thumb rect 0 0 200 200 O. J. Simpson murder case rect 200 0 400 200 Kobe earthquake rect 400 0 600 200 Unabomber Manifesto rect 0 200 300 400 Oklahoma City bombing rect 300 200 600 400 Srebrenica massacre rect 0 400 200 600 Space Shuttle Atlant ...
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1914 Births
This year saw the beginning of what became known as World War I, after Archduke Franz Ferdinand of Austria, heir to the Austrian throne was assassinated by Serbian nationalist Gavrilo Princip. It also saw the first airline to provide scheduled regular commercial passenger services with heavier-than-air aircraft, with the St. Petersburg–Tampa Airboat Line. Events January * January 1 – The St. Petersburg–Tampa Airboat Line in the United States starts services between St. Petersburg and Tampa, Florida, becoming the first airline to provide scheduled regular commercial passenger services with heavier-than-air aircraft, with Tony Jannus (the first federally-licensed pilot) conveying passengers in a Benoist XIV flying boat. Abram C. Pheil, mayor of St. Petersburg, is the first airline passenger, and over 3,000 people witness the first departure. * January 11 – The Sakurajima volcano in Japan begins to erupt, becoming effusive after a very large earthquake ...
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Brazilian Biochemists
Brazilian commonly refers to: * Something of, from or relating to Brazil * Brazilian Portuguese, the dialect of the Portuguese language used mostly in Brazil * Brazilians, the people (citizens) of Brazil, or of Brazilian descent Brazilian may also refer to: Sports * Brazilian football, see football in Brazil * Brazilian jiu-jitsu, a martial art and combat sport system *''The Brazilians'', a nickname for South African football association club Mamelodi Sundowns F.C. due to their soccer kits which resembles that of the Brazilian national team Other uses * Brazilian waxing, a style of Bikini waxing * Brazilian culture, describing the Culture of Brazil * "The Brazilian", a 1986 instrumental by Genesis * Brazilian barbecue, known as churrasco * Brazilian cuisine See also * ''Brasileiro ''Brasileiro'' is a 1992 album by Sérgio Mendes and other artists including Carlinhos Brown which won the 1993 Grammy Award for Best World Music Album. Track listing # "Fanfarra" (Carlinhos Brown) ...
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Universidade De São Paulo
The Universiade is an international multi-sport event, organized for university athletes by the International University Sports Federation (FISU). The name is a portmanteau of the words "University" and "Olympiad". The Universiade is referred to in English as the World University Games or World Student Games; however, this latter term can also refer to competitions for sub-University grades students. In July 2020 as part of a new branding system by the FISU, it was stated that the Universiade will be officially branded as the FISU World University Games. The most recent games were held in 2019: the Winter Universiade was held in Krasnoyarsk, Russia while the Summer Universiade was held in Naples, Italy. The next Winter World University Games are scheduled to be held in Lake Placid, United States between 11–21 January 2023, after the 2021 edition scheduled to be held in Lucerne, Switzerland was cancelled due the COVID-19 pandemic. The 2021 Summer World University Games were s ...
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Faculdade De Medicina De Ribeirão Preto
Faculdade de Medicina de Ribeirão Preto (Ribeirão Preto Medical School in Portuguese) is a medical school of the University of São Paulo (USP) located in the city of Ribeirão Preto, state of São Paulo, Brazil, founded in 1952. It is considered one of the three best medical schools in the country and a premier medical research center. Its main campus is located in a charming old coffee farm in the outskirts of the city, with a total built area of , including a small lake. It has a central building with the main departments for the basic medical sciences and an adjoining University Hospital, with 847 beds. In 2003, the hospital provided in-patient care to 33,973 persons and out-patient (ambulatory) care to approximately 588,000. All medical care is provided free of charge. History The Ribeirão Preto Medical School was the third founded in the state of São Paulo and the first outside the capital. In 1951, the state government supported the creation of the school as a way of ...
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Ribeirão Preto
Ribeirão Preto (Portuguese pronunciation: ibejˈɾɐ̃w ˈpɾetu is a municipality and a metropolitan area located in the northeastern region of São Paulo state, Brazil. Ribeirão Preto is the eighth-largest municipality in the State with . It has an estimated population of 720,216 in 2021 and a metropolitan area of 1,178,910. It is located from the city of São Paulo and from Brasília, the federal capital. Its mean altitude is high. The city's average temperature throughout the year is , and the original predominant vegetation is the Atlantic forest. The city originated around 1856 as an agricultural region. Coffee was a primary income source until 1929 when it lost value compared with the industrial sector. In the second half of the 20th century, investment in health, biotechnology, bioenergy, and information technology led to the city being declared a Technological Center in 2010. These activities have caused the city to have the 30th biggest gross national (GNP ...
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Zeferino Vaz
Zeferino Vaz (May 27, 1908 – February 19, 1981) led the construction, establishment and development of the Unicamp university, in the interior of the State of São Paulo, Brazil in the 1960s and 1970s. The main campus is named after Zeferino, who strived to bring together some of Brazil's best scientists to form a recognised research institution. Zeferino was born and lived his childhood in São Paulo. He attended the Medicine school of the University of São Paulo and got his M.D. degree in 1932, with specializations in Parasitology, Parasitic Diseases, Biology, Genetics and Zoology. Shortly after his graduation, Zeferino became professor of Zoology and Parasitology in the Veterinary Medicine School of the University of São Paulo. He was the director of the Veterinary Medicine School from 1936 to 1947. From 1951 to 1964 he was the director-founder of the Medical School of Ribeirão Preto, and during this period, in 1963, he was state secretary of public health. From 196 ...
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Crotamine
Crotamine is a toxin present in the venom of the South American rattlesnake ('' Crotalus durissus terrificus''). It is a 42-residue long protein containing 11 basic residues (9 lysines, 2 arginines) and 6 cysteines. It has also been isolated from the venom of North American prairie rattlesnake, ''Crotalus viridis viridis''. It was first isolated and purified by Brazilian scientist José Moura Gonçalves, and later intensively studied by his group of collaborators at the Medical School of Ribeirão Preto of the University of São Paulo. Biological function Crotamine has a number of biological actions: it acts on cell membrane's sodium channels, is slightly analgesic and is myotoxic, i.e., it penetrates the cells of muscles and promotes necrosis. Crotamine is homologous with other venom myotoxins and is similar to α-,β-defensins. Biochemistry and mechanism The amino acid sequence (, Cys4-Cys36, Cys11-Cys30, Cys18-Cys37) and the 3D molecular structure of crotamine have already be ...
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