Joseph Takahashi
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Joseph Takahashi
Joseph S. Takahashi is a Japanese American neurobiologist and geneticist. Takahashi is a professor at University of Texas Southwestern Medical Center as well as an investigator at the Howard Hughes Medical Institute. Takahashi's research group discovered the genetic basis for the mammalian circadian clock in 1994 and identified the ''Clock'' gene in 1997. Takahashi was elected to the National Academy of Sciences in 2003. Background Takahashi graduated from Richard Montgomery High School in Rockville, Maryland in 1970. Takahashi attended Swarthmore College and graduated with a degree in biology in 1974. He worked with Patricia DeCoursey at the University of South Carolina for a year after graduation and then applied to work with Michael Menaker at the University of Texas, Austin. Menaker ultimately moved to the University of Oregon where Takahashi received his neuroscience Ph.D. in 1981. Takahashi was a postdoctoral fellow at the National Institute of Mental Health for two years ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ...
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Richard Montgomery High School
Richard Montgomery High School (RMHS) (#201) is a secondary public school located in Rockville, Maryland. Academics The school houses Montgomery County's first International Baccalaureate Diploma Programme (IB). This competitive-entry magnet program draws students from all over Montgomery County and has an IB diploma rate of 97%, the highest of its kind in the United States. The IB program has a 10% acceptance rate for incoming freshmen. Entry is based on an entrance examination, middle school transcripts, teacher recommendations, and personal essays. Incoming freshmen who have been accepted into the IB program are first enrolled in a special two-year program consisting of courses designed to prepare them for more rigorous IB courses they will take in their junior and senior years. This also serves as a continuation of the final two years of the Middle Years Programme (MYP). The first three years of the MYP program are offered to all students who attend Julius West Middle School, ...
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Michael E
SS ''Michael E'' was a cargo ship that was built in 1941. She was the first British Catapult Aircraft Merchant ship: a merchant ship fitted with a rocket catapult to launch a single Hawker Hurricane fighter to defend a convoy against long-range German bombers. She was sunk on her maiden voyage by a German submarine. Description ''Michael E'' was built by William Hamilton & Co Ltd, Port Glasgow. Launched in 1941, she was completed in May of that year. She was the United Kingdom's first CAM ship, armed with an aircraft catapult on her bow to launch a Hawker Sea Hurricane. The ship was long between perpendiculars ( overall), with a beam of . She had a depth of and a draught of . She was and . She had six corrugated furnaces feeding two 225 lbf/in2 single-ended boilers with a combined heating surface of . The boilers fed a 443 NHP triple-expansion steam engine that had cylinders of , and diameter by stroke. The engine was built by David Rowan & Co Ltd, Glasgow. History ...
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Homeothermic
Homeothermy, homothermy or homoiothermy is thermoregulation that maintains a stable internal body temperature regardless of external influence. This internal body temperature is often, though not necessarily, higher than the immediate environment (from Greek ὅμοιος ''homoios'' "similar" and θέρμη ''thermē'' "heat"). Homeothermy is one of the three types of thermoregulation in warm-blooded animal species. Homeothermy's opposite is poikilothermy. A poikilotherm is an organism that does not maintain a fixed internal temperature but rather fluctuates based on their environment and physical behaviour. Homeotherms are ''not'' necessarily endothermic. Some homeotherms may maintain constant body temperatures through behavioral mechanisms alone, ''i.e.'', behavioral thermoregulation. Many reptiles use this strategy. For example, desert lizards are remarkable in that they maintain near-constant activity temperatures that are often within a degree or two of their lethal critic ...
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Hypothalamus
The hypothalamus () is a part of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions is to link the nervous system to the endocrine system via the pituitary gland. The hypothalamus is located below the thalamus and is part of the limbic system. In the terminology of neuroanatomy, it forms the ventral part of the diencephalon. All vertebrate brains contain a hypothalamus. In humans, it is the size of an almond. The hypothalamus is responsible for regulating certain metabolic processes and other activities of the autonomic nervous system. It synthesizes and secretes certain neurohormones, called releasing hormones or hypothalamic hormones, and these in turn stimulate or inhibit the secretion of hormones from the pituitary gland. The hypothalamus controls body temperature, hunger, important aspects of parenting and maternal attachment behaviours, thirst, fatigue, sleep, and circadian rhythms. Structure T ...
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Suprachiasmatic Nucleus
The suprachiasmatic nucleus or nuclei (SCN) is a tiny region of the brain in the hypothalamus, situated directly above the optic chiasm. It is responsible for controlling circadian rhythms. The neuronal and hormonal activities it generates regulate many different body functions in a 24-hour cycle. The mouse SCN contains approximately 20,000 neurons. The SCN interacts with many other regions of the brain. It contains several cell types and several different peptides (including vasopressin and vasoactive intestinal peptide) and neurotransmitters. Neuroanatomy The SCN is situated in the anterior part of the hypothalamus immediately dorsal, or ''superior'' (hence supra) to the optic chiasm (CHO) bilateral to (on either side of) the third ventricle. The nucleus can be divided into ventrolateral and dorsolateral portions, also known as the core and shell, respectively. These regions differ in their expression of the clock genes, the core expresses them in response to stimuli whereas ...
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Pineal Gland
The pineal gland, conarium, or epiphysis cerebri, is a small endocrine gland in the brain of most vertebrates. The pineal gland produces melatonin, a serotonin-derived hormone which modulates sleep, sleep patterns in both circadian rhythm, circadian and Season, seasonal cycles. The shape of the gland resembles a pine cone, which gives it its name. The pineal gland is located in the epithalamus, near the center of the brain, between the two cerebral hemisphere, hemispheres, tucked in a groove where the two halves of the thalamus join. The pineal gland is one of the neuroendocrinology, neuroendocrine Circumventricular organs, secretory circumventricular organs in which capillaries are mostly Vascular permeability, permeable to solutes in the blood. Nearly all vertebrate species possess a pineal gland. The most important exception is a primitive vertebrate, the hagfish. Even in the hagfish, however, there may be a "pineal equivalent" structure in the dorsal diencephalon. The lanc ...
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Neuron (journal)
''Neuron'' is a biweekly peer-reviewed scientific journal published by Cell Press, and imprint of Elsevier. It was established in 1988, and covers neuroscience and related biological processes. The current editor in chief is Mariela Zirlinger. The founding editors were Lily Jan, A. James Hudspeth, Louis Reichardt Louis French Reichardt (born June 4, 1942) is a noted American neuroscientist and mountaineering, mountaineer, the first American to summit both Everest and K2. He was also director of the Simons Foundation Autism Research Initiative, the largest ..., Roger Nicoll, and Zach Hall. A past Editor in Chief was Katja Brose. Transcript and video available. Click on "Transcript" for text. * See alsoA Career in Science Editing: Katja BroseEditor in Chief, Neuron References External links * Neuroscience journals Cell Press academic journals Publications established in 1988 English-language journals Biweekly journals {{neuroscience-journal-stub ...
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University Of Texas Southwestern Medical Center At Dallas
The University of Texas Southwestern Medical Center (UT Southwestern or UTSW) is a public academic health science center in Dallas, Texas. With approximately 18,800 employees, more than 2,900 full-time faculty, and nearly 4 million outpatient visits per year, UT Southwestern is the largest medical school in the University of Texas System and state of Texas.https://utsystem.edu/sites/default/files/documents/publication/2018/fast-facts/fast-facts-09-2018.pdf UT Southwestern's William P. Clements Jr University Hospital is nationally ranked in nine specialties by '' U.S. News & World Report'' and ranked the best hospital in the Dallas-Fort Worth/North Texas region. Forbes ranked UT Southwestern Medical Center as the top health care employer in the state of Texas and the top health care employer to new graduates in the United States. UT Southwestern's operating budget in 2021 was more than $4.1 billion, and is the largest medical institution in the Dallas–Fort Worth Metroplex (a ...
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Northwestern University
Northwestern University is a private research university in Evanston, Illinois. Founded in 1851, Northwestern is the oldest chartered university in Illinois and is ranked among the most prestigious academic institutions in the world. Chartered by the Illinois General Assembly in 1851, Northwestern was established to serve the former Northwest Territory. The university was initially affiliated with the Methodist Episcopal Church but later became non-sectarian. By 1900, the university was the third largest university in the United States. In 1896, Northwestern became a founding member of the Big Ten Conference, and joined the Association of American Universities as an early member in 1917. The university is composed of eleven undergraduate, graduate, and professional schools, which include the Kellogg School of Management, the Pritzker School of Law, the Feinberg School of Medicine, the Weinberg College of Arts and Sciences, the Bienen School of Music, the McCormick ...
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National Institute Of Mental Health
The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. NIMH is the largest research organization in the world specializing in mental illness. Joshua A. Gordon is the current director of NIMH. The institute was first authorized by the U.S. government in 1946, when then President Harry Truman signed into law the National Mental Health Act, although the institute was not formally established until 1949. NIMH is a $1.5 billion enterprise, supporting research on mental health through grants to investigators at institutions and organizations throughout the United States and through its own internal (intramural) research effort. The mission of NIMH is "to transform the understanding and treatment of m ...
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Postdoctoral Fellow
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ...
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