John Rodman Paul
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John Rodman Paul
John Rodman Paul (April 18, 1893 – May 6, 1971) was an American virologist whose research focused on the spread of polio and the development of treatments for the disease. Life and achievements Paul was born on April 18, 1893, in Philadelphia. He earned his undergraduate degree in 1915 from Princeton University and received his medical training at Johns Hopkins School of Medicine, which awarded him an M.D. degree.Staff"Dr. John Paul, Polio Researcher, Dies" ''The New York Times'', May 7, 1971. Accessed September 27, 2010. He began his career as an assistant pathologist at Johns Hopkins in 1919 and 1920, and followed that with an internship at Pennsylvania Hospital in Philadelphia from 1920 to 1922. In 1928, Paul joined the faculty of the Yale School of Medicine as a professor of internal medicine and held the position of professor of preventive medicine starting in 1940, which he retained until his retirement. Paul established the Yale Poliomyelitis Study Unit in 1931 tog ...
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Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since 1854, the city has been coextensive with Philadelphia County, the most populous county in Pennsylvania and the urban core of the Delaware Valley, the nation's seventh-largest and one of world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, an English Quaker. The city served as capital of the Pennsylvania Colony during the British colonial era and went on to play a historic and vital role as the central meeting place for the nation's founding fathers whose plans and actions in Philadelphia ultimately inspired the American Revolution and the nation's inde ...
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Guilford, Connecticut
Guilford is a town in New Haven County, Connecticut, United States, that borders Madison, Branford, North Branford and Durham, and is situated on I-95 and the Connecticut seacoast. The population was 22,073 at the 2020 census. History Guilford was named after the town of Guildford, in England, the native home of a share of its first settlers. In early maps of the Connecticut Colony, the town is seen on several maps as Gilford. First settled by Europeans in 1639 after a treaty with the “Sachem Squaw” Shaumpishuh. Guilford is considered by some to have the third largest collection of historic homes in New England, with important buildings from the 17th, 18th, and 19th centuries. There are five historic house museums, including Dudley Farm and the Henry Whitfield House (1639), the oldest dwelling house in Connecticut and the oldest stone house built by English settlers in North America. The Comfort Starr House (1695) is one of the oldest wooden framed private dwellings in C ...
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Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Char ...
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Wendy Orent
Wendy Orent is an American anthropologist and science writer with a focus on pandemics, biological weapons, and the evolution of infectious diseases. She is a freelance science writer whose work has appeared in "The Washington Post", "Aeon", "Undark Magazine", "The Sciences", "The Los Angeles Times", "The New Republic", "Discover", and "The American Prospect". Life Orent assisted Russian scientist Igor Domaradskij in the writing of his memoir, ''Biowarrior: Inside the Soviet/Russian Biological War Machine''. Domaradskij credits himself with much of the research leading to the creation of an antibiotic resistant strain of ''Yersinia pestis'', the plague germ. Domaradskij, the co-designer of the entire Soviet biological weapons program known as Biopreparat, carried out the research leading to the creation of an antibiotic resistant strain of Yersinia pestis, the plague germ. She discussed this in her own book, Plague: The Mysterious Past and Terrifying Future of the World's Most Dan ...
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Albert B
Albert may refer to: Companies * Albert (supermarket), a supermarket chain in the Czech Republic * Albert Heijn, a supermarket chain in the Netherlands * Albert Market, a street market in The Gambia * Albert Productions, a record label * Albert Computers, Inc., a computer manufacturer in the 1980s Entertainment * ''Albert'' (1985 film), a Czechoslovak film directed by František Vláčil * ''Albert'' (2015 film), a film by Karsten Kiilerich * ''Albert'' (2016 film), an American TV movie * ''Albert'' (Ed Hall album), 1988 * "Albert" (short story), by Leo Tolstoy * Albert (comics), a character in Marvel Comics * Albert (''Discworld''), a character in Terry Pratchett's ''Discworld'' series * Albert, a character in Dario Argento's 1977 film ''Suspiria'' Military * Battle of Albert (1914), a WWI battle at Albert, Somme, France * Battle of Albert (1916), a WWI battle at Albert, Somme, France * Battle of Albert (1918), a WWI battle at Albert, Somme, France People * Albert (given ...
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United States Public Health Service
The United States Public Health Service (USPHS or PHS) is a collection of agencies of the Department of Health and Human Services concerned with public health, containing nine out of the department's twelve operating divisions. The Assistant Secretary for Health oversees the PHS. The Public Health Service Commissioned Corps (PHSCC) is the federal uniformed service of the PHS, and is one of the eight uniformed services of the United States. PHS had its origins in the system of marine hospitals that originated in 1798. In 1871 these were consolidated into the Marine Hospital Service, and shortly afterwards the position of Surgeon General and the PHSCC were established. As the system's scope grew to include quarantine authority and research, it was renamed the Public Health Service in 1912. A series of reorganizations in 1966–1973 began a shift where PHS' divisions were promoted into departmental operating agencies. PHS was established as a thin layer of hierarchy above ...
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Rheumatic Fever
Rheumatic fever (RF) is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a streptococcal throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and occasionally a characteristic non-itchy rash known as erythema marginatum. The heart is involved in about half of the cases. Damage to the heart valves, known as rheumatic heart disease (RHD), usually occurs after repeated attacks but can sometimes occur after one. The damaged valves may result in heart failure, atrial fibrillation and infection of the valves. Rheumatic fever may occur following an infection of the throat by the bacterium ''Streptococcus pyogenes''. If the infection is left untreated, rheumatic fever occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Due to their genetics, some peo ...
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Infectious Mononucleosis
Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). Most people are infected by the virus as children, when the disease produces few or no symptoms. In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and tiredness. Most people recover in two to four weeks; however, feeling tired may last for months. The liver or spleen may also become swollen, and in less than one percent of cases splenic rupture may occur. While usually caused by the Epstein–Barr virus, also known as human herpesvirus 4, which is a member of the herpesvirus family, a few other viruses may also cause the disease. It is primarily spread through saliva but can rarely be spread through semen or blood. Spread may occur by objects such as drinking glasses or toothbrushes or through a cough or sneeze. Those who are infected can spread the disease weeks before symptoms develop. Mono is p ...
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Hepatitis
Hepatitis is inflammation of the liver tissue. Some people or animals with hepatitis have no symptoms, whereas others develop yellow discoloration of the skin and whites of the eyes (jaundice), poor appetite, vomiting, tiredness, abdominal pain, and diarrhea. Hepatitis is ''acute'' if it resolves within six months, and '' chronic'' if it lasts longer than six months. Acute hepatitis can resolve on its own, progress to chronic hepatitis, or (rarely) result in acute liver failure. Chronic hepatitis may progress to scarring of the liver (cirrhosis), liver failure, and liver cancer. Hepatitis is most commonly caused by the virus ''hepatovirus A'', '' B'', '' C'', '' D'', and '' E''. Other viruses can also cause liver inflammation, including cytomegalovirus, Epstein–Barr virus, and yellow fever virus. Other common causes of hepatitis include heavy alcohol use, certain medications, toxins, other infections, autoimmune diseases, and non-alcoholic steatohepatitis (NASH). Hepa ...
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Soviet Union
The Soviet Union,. officially the Union of Soviet Socialist Republics. (USSR),. was a transcontinental country that spanned much of Eurasia from 1922 to 1991. A flagship communist state, it was nominally a federal union of fifteen national republics; in practice, both its government and its economy were highly centralized until its final years. It was a one-party state governed by the Communist Party of the Soviet Union, with the city of Moscow serving as its capital as well as that of its largest and most populous republic: the Russian SFSR. Other major cities included Leningrad (Russian SFSR), Kiev (Ukrainian SSR), Minsk ( Byelorussian SSR), Tashkent (Uzbek SSR), Alma-Ata (Kazakh SSR), and Novosibirsk (Russian SFSR). It was the largest country in the world, covering over and spanning eleven time zones. The country's roots lay in the October Revolution of 1917, when the Bolsheviks, under the leadership of Vladimir Lenin, overthrew the Russian Provisional Government ...
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Poliovirus
A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species ''Enterovirus C'', in the family of ''Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only RNA and a nonenveloped icosahedral protein coat that encapsulates it—poliovirus is widely regarded as the simplest significant virus. Poliovirus was first isolated in 1909 by Karl Landsteiner and Erwin Popper. The structure of the virus was first elucidated in 1958 using X-ray diffraction by a team at Birkbeck College led by Rosalind Franklin, showing the polio virus to have icosahedral symmetry. In 1981, the poliovirus genome was published by two different teams ...
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