John R. Riordan
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John R. Riordan
John Richard Riordan, OC (Also known as Jack) (born September 2, 1943, in St. Stephen, New Brunswick) is a Canadian biochemist, noted for his research into cystic fibrosis. After acquiring his bachelor's degree in 1966 from the University of Toronto, he studied and received a doctorate in biochemistry from the same university in 1970. His next three years were spent at the Max Planck Institute for Biophysics in Frankfurt. He then returned to the University of Toronto, where he worked as a professor in the Biochemistry department from 1974. Prior to retiring in 2018, Riordan was a professor at the University of North Carolina at Chapel Hill where he was a member of the Biochemistry and Biophysics Department studying the structure and function of CFTR. He is also a visiting scientist at the Academy Salhgrenska (where he holds an honorary doctorate ) and University of Gothenburg. He is mostly recognized for the first ever discovery of a mutated gene, ΔF508, that can cause cystic fib ...
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University Of Toronto
The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution of higher learning in Upper Canada. Originally controlled by the Church of England, the university assumed its present name in 1850 upon becoming a secular institution. As a collegiate university, it comprises eleven colleges each with substantial autonomy on financial and institutional affairs and significant differences in character and history. The university maintains three campuses, the oldest of which, St. George, is located in downtown Toronto. The other two satellite campuses are located in Scarborough and Mississauga. The University of Toronto offers over 700 undergraduate and 200 graduate programs. In all major rankings, the university consistently ranks in the top ten public universities in the world and as the top university ...
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Max Planck Institute For Biophysics
The Max Planck Institute of Biophysics (german: Max-Planck-Institut für Biophysik) is located in Frankfurt, Germany. It was founded as the Kaiser Wilhelm Institute of Biophysics in 1937, and moved into a new building in 2003. It is an institute of the Max Planck Society. Since March 2003, the MPI for Biophysics has resided in a new building on the Riedberg campus of the Goethe University Frankfurt in the north of the city. At the end of 2016, a total of 178 employees were working at the institute, including 48 scientists and 50 junior researchers. The Nobel Prize winner Hartmut Michel has been director of the institute since 1987. Scientific links to fellow researchers at Goethe University have been strengthened further, as the institute is now situated next to the university's biology, chemistry and physics laboratories. Together with the Max Planck Institute for Brain Research and the Goethe University the institute run the ''International Max Planck Research School (IMPRS) fo ...
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Frankfurt
Frankfurt, officially Frankfurt am Main (; Hessian: , "Frank ford on the Main"), is the most populous city in the German state of Hesse. Its 791,000 inhabitants as of 2022 make it the fifth-most populous city in Germany. Located on its namesake Main River, it forms a continuous conurbation with the neighboring city of Offenbach am Main and its urban area has a population of over 2.3 million. The city is the heart of the larger Rhine-Main metropolitan region, which has a population of more than 5.6 million and is Germany's second-largest metropolitan region after the Rhine-Ruhr region. Frankfurt's central business district, the Bankenviertel, lies about northwest of the geographic center of the EU at Gadheim, Lower Franconia. Like France and Franconia, the city is named after the Franks. Frankfurt is the largest city in the Rhine Franconian dialect area. Frankfurt was a city state, the Free City of Frankfurt, for nearly five centuries, and was one of the most import ...
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University Of North Carolina At Chapel Hill
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The unive ...
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CFTR
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and anion channel in vertebrates that is encoded by the ''CFTR'' gene. Geneticist Lap-Chee Tsui and his team identified the CFTR gene in 1989 as the gene linked with CF (CYSTIC FIBROSIS). The CFTR gene codes for an ABC transporter-class ion channel protein that conducts chloride and bicarbonate ions across epithelial cell membranes. Mutations of the CFTR gene affecting anion channel function lead to dysregulation of epithelial lining fluid (mucus) transport in the lung, pancreas and other organs, resulting in cystic fibrosis. Complications include thickened mucus in the lungs with frequent respiratory infections, and pancreatic insufficiency giving rise to malnutrition and diabetes. These conditions lead to chronic disability and reduced life expectancy. In male patients, the progressive obstruction and destruction of the developing vas deferens (spermatic cord) and epididymis appear to result from ...
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University Of Gothenburg
The University of Gothenburg ( sv, Göteborgs universitet) is a university in Sweden's second largest city, Gothenburg. Founded in 1891, the university is the third-oldest of the current Swedish universities and with 37,000 students and 6000 staff members it is one of the largest universities in the Nordic countries. About With its eight faculties and 38 departments, the University of Gothenburg is one of the most wide-ranging and versatile universities in Sweden. Its eight faculties offer training in the Creative Arts, Social Sciences, Natural Sciences, Humanities, Education, Information Technology, Business, Economics and Law, and Health Sciences. The University of Gothenburg has the highest number of applicants per study place in many of its subjects and courses, making it one of the most popular universities in Sweden. History The University of Gothenburg was founded as ''Göteborgs högskola'' (Gothenburg University College) in 1891. In 1907 it was granted the same s ...
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ΔF508
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and anion channel in vertebrates that is encoded by the ''CFTR'' gene. Geneticist Lap-Chee Tsui and his team identified the CFTR gene in 1989 as the gene linked with CF (CYSTIC FIBROSIS). The CFTR gene codes for an ABC transporter-class ion channel protein that conducts chloride and bicarbonate ions across epithelial cell membranes. Mutations of the CFTR gene affecting anion channel function lead to dysregulation of epithelial lining fluid (mucus) transport in the lung, pancreas and other organs, resulting in cystic fibrosis. Complications include thickened mucus in the lungs with frequent respiratory infections, and pancreatic insufficiency giving rise to malnutrition and diabetes. These conditions lead to chronic disability and reduced life expectancy. In male patients, the progressive obstruction and destruction of the developing vas deferens (spermatic cord) and epididymis appear to result from ...
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Francis Collins
Francis Sellers Collins (born April 14, 1950) is an American physician-geneticist who discovered the genes associated with a number of diseases and led the Human Genome Project. He is the former director of the National Institutes of Health (NIH) in Bethesda, Maryland, from 17 August 2009 to 19 December 2021, serving under three presidents, and for over 12 years. Before being appointed director of the NIH, Collins led the Human Genome Project and other genomics research initiatives as director of the National Human Genome Research Institute (NHGRI), one of the 27 institutes and centers at NIH. Before joining NHGRI, he earned a reputation as an LSU Fan at the University of Michigan. He has been elected to the Institute of Medicine and the National Academy of Sciences, and has received the Presidential Medal of Freedom and the National Medal of Science. Collins also has written a number of books on science, medicine, and religion, including the ''New York Times'' bestseller, '' ...
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Lap-Chee Tsui
Lap-Chee Tsui (; born 21 December 1950) is a Chinese-born Canadian geneticist and served as the 14th Vice-Chancellor and President of the University of Hong Kong. Personal life Tsui was born in Shanghai. He grew up in Kowloon, Hong Kong and attended Homantin Government Secondary School. He studied Biology at the New Asia College of the Chinese University of Hong Kong and was awarded a B.Sc. (3rd Class Honours) and a M.Phil. in 1972 and 1974, respectively. Upon the recommendation of his mentor at the CUHK, he continued his graduate education in the United States and received his Ph.D. from the University of Pittsburgh in 1979. He became Postdoctoral Investigator and Postdoctoral Fellow in 1979 at Oak Ridge National Laboratory, Tennessee, then joined the Department of Genetics of the Hospital for Sick Children in Toronto in 1981. Career From 1981 to 2002, Tsui continued his research and teaching in the Hospital for Sick Children and the University of Toronto alternatively. Pri ...
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1943 Births
Events Below, the events of World War II have the "WWII" prefix. January * January 1 – WWII: The Soviet Union announces that 22 German divisions have been encircled at Stalingrad, with 175,000 killed and 137,650 captured. * January 4 – WWII: Greek-Polish athlete and saboteur Jerzy Iwanow-Szajnowicz is executed by the Germans at Kaisariani. * January 11 ** The United States and United Kingdom revise previously unequal treaty relationships with the Republic of China (1912–1949), Republic of China. ** Italian-American anarchist Carlo Tresca is assassinated in New York City. * January 13 – Anti-Nazi protests in Sofia result in 200 arrests and 36 executions. * January 14 – January 24, 24 – WWII: Casablanca Conference: Franklin D. Roosevelt, President of the United States; Winston Churchill, Prime Minister of the United Kingdom; and Generals Charles de Gaulle and Henri Giraud of the Free French forces meet secretly at the Anfa Hotel in Casablanca, Morocco, to plan the ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Canadian Biochemists
Canadians (french: Canadiens) are people identified with the country of Canada. This connection may be residential, legal, historical or cultural. For most Canadians, many (or all) of these connections exist and are collectively the source of their being ''Canadian''. Canada is a multilingual and multicultural society home to people of groups of many different ethnic, religious, and national origins, with the majority of the population made up of Old World immigrants and their descendants. Following the initial period of French and then the much larger British colonization, different waves (or peaks) of immigration and settlement of non-indigenous peoples took place over the course of nearly two centuries and continue today. Elements of Indigenous, French, British, and more recent immigrant customs, languages, and religions have combined to form the culture of Canada, and thus a Canadian identity. Canada has also been strongly influenced by its linguistic, geographic, and ec ...
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