John Maurice Hardman Campbell
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John Maurice Hardman Campbell
John Maurice Hardman Campbell (1891–1973) was a British physician, cardiologist, and medical journal editor. Biography After education at Winchester College, J. Maurice Campbell studied at New College, Oxford, where he graduated with a first-class honours degree in physiology. He was awarded a senior demyship at Magdalen College, Oxford and entered in 1914 Guy's Hospital Medical School, where he graduated in 1916 BM BCh (Oxon.). He joined in 1916 the RAMC, served with the rank of captain in Mesopotamia and North Persia, and was twice mentioned in despatches. In June 1919 he was awarded the OBE for his services with a field ambulance. In 1920 Campbell returned to Guy's Hospital as a medical registrar. He graduated DM in 1921 and qualified MRCP in 1921. He spent three years (from 1923 to 1925) in the department of physiology working with E. P. Poulton on oxygen therapy and with Marcus Pembrey. Campbell held from 1923 to 1927 a Beit memorial research fellowship, in 1925 ...
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Headington, Oxfordshire
Headington is an eastern suburb of Oxford, England. It is at the top of Headington Hill overlooking the city in the Thames valley below, and bordering Marston to the north-west, Cowley to the south, and Barton and Risinghurst to the east. The life of the large residential area is centred upon London Road, the main road between London and Oxford. History The site of Headington shows evidence of continued occupation from the Stone Age, as the 2001 field excavations in Barton Lane found, suggesting a date in the 11th century BC. Pottery was found on the Manor Ground, suggesting an Iron Age settlement there in the 7th century BC. Roman kilns from about 300 have been found, including one now on display at the Museum of Oxford. Anglo-Saxon burial remains from about 500 have also been discovered. Headington's toponym is derived from the Old English ''Hedena's dun'', meaning "Hedena's hill", when it was the site of a palace or hunting lodge of the Kings of Mercia. In a charter of 1 ...
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Quinidine
Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances. It is the enantiomer of antimalarial agent quinine, originally derived from the bark of the cinchona tree. The drug causes increased action potential duration, as well as a prolonged QT interval. As of 2019, its IV formulation is no longer being manufactured for use in the United States. Medical uses Quinidine is occasionally used as a class I antiarrhythmic agent to prevent ventricular arrhythmias, particularly in Brugada Syndrome, although its safety in this indication is uncertain. It reduces the recurrence of atrial fibrillation after patients undergo cardioversion, but it has proarrhythmic effects and trials suggest that it may lead to an overall increased mortality in these patients. Quinidine is also used to treat short QT syndrome. Eli Lilly has discontinued manufacture of parenteral quinidine gluconate in the US, and its future availability in many countries is uncertain. Other ...
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British Cardiac Society
The British Cardiovascular Society (BCS) is a United Kingdom-wide health organisation based in London. It aims to represent all healthcare professionals working in the field of cardiology, set standards for prevention, diagnosis, and clinical care, and communicate those standards to the community and the patients through training, education and public outreach. History The first idea for the BCS came in 1910 by the Scottish cardiologist Sir James Mackenzie. At an Association of Physicians meeting in Oxford on 22 April 1922, the Cardiac Club was formed by 5 cardiologists: Carey F. Coombs, T. F. Cotton, John Cowan, A. G. Gibson (as chair), and W. E. Hume. It was founded in 1922 at the Club's first active meeting by 15 founder members — the original five plus ten others, including Thomas J. Horder and Thomas Lewis — and with one honorary member, namely Mackenzie. In April 1937 it became the Cardiac Society of Great Britain and Ireland. In 1946 it became the British Cardiac S ...
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Lumleian Lectures
The Lumleian Lectures are a series of annual lectures started in 1582 by the Royal College of Physicians and currently run by the Lumleian Trust. The name commemorates John Lumley, 1st Baron Lumley, who with Richard Caldwell of the College endowed the lectures, initially confined to surgery, but now on general medicine. William Harvey did not announce his work on the circulation of the blood in the Lumleian Lecture for 1616 although he had some partial notes on the heart and blood which led to the discovery of the circulation ten years later. By that time ambitious plans for a full anatomy course based on weekly lectures had been scaled back to a lecture three times a year. Initially the appointment of the Lumleian lecturer was for life, later reduced to five years, and since 1825 made annually, although for some years it was awarded for two years in succession. ebooks Lecturers (incomplete list) 1811–1900 1901-2000 2001 onwards *2003 Rodney Phillips, ''Immunology as ta ...
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Mitral Stenosis
Mitral stenosis is a valvular heart disease characterized by the narrowing of the opening of the mitral valve of the heart. It is almost always caused by rheumatic valvular heart disease. Normally, the mitral valve is about 5 cm2 during diastole. Any decrease in area below 2 cm2 causes mitral stenosis. Early diagnosis of mitral stenosis in pregnancy is very important as the heart cannot tolerate increased cardiac output demand as in the case of exercise and pregnancy. Atrial fibrillation is a common complication of resulting left atrial enlargement, which can lead to systemic thromboembolic complications like stroke. Signs and symptoms Signs and symptoms of mitral stenosis include the following: * Heart failure symptoms, such as dyspnea on exertion, orthopnea and paroxysmal nocturnal dyspnea (PND) * Palpitations * Chest pain * Hemoptysis * Thromboembolism in later stages when the left atrial volume is increased (i.e., dilation). The latter leads to increase risk of ...
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Russell Brock, Baron Brock
Russell Claude Brock, Baron Brock (24 October 1903 – 3 September 1980) was a leading British chest and heart surgeon and one of the pioneers of modern open-heart surgery. His achievements were recognised by a Knighthood in 1954, a Life Peerage in 1965, and a host of other awards. Biography He was born in London, 1903, the son of Herbert Brock, a master photographer, and his wife, Elvina (née Carman). He was the second of six sons and fourth of eight children. He was educated at Haselrigge Road School, Clapham, and then at Christ's Hospital, Horsham, where he later became an Almoner (governor). He entered Guy's Hospital Medical School in 1921 at age 17 with an arts scholarship. He qualified LRCP (Lond.) and MRCS (Eng.) 1926, and graduated MB, BS (Lond.) with honours and distinction in medicine, surgery, and anatomy in 1927. He was appointed demonstrator in anatomy and in pathology at Guy's and passed the final FRCS (Eng.) in 1929.Dictionary of National Biography(2004-8)Th ...
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Cyanotic Heart Defect
A cyanotic heart defect is any congenital heart defect (CHD) that occurs due to deoxygenated blood bypassing the lungs and entering the systemic circulation, or a mixture of oxygenated and unoxygenated blood entering the systemic circulation. It is caused by structural defects of the heart such as right-to-left or bidirectional shunting, malposition of the great arteries, or any condition which increases pulmonary vascular resistance. The result may be the development of collateral circulation. Types * Tetralogy of Fallot (ToF) * Total anomalous pulmonary venous connection * Hypoplastic left heart syndrome (HLHS) * Transposition of the great arteries (d-TGA) * Truncus arteriosus (Persistent) * Tricuspid atresia * Interrupted aortic arch * Pulmonary atresia (PA) * Pulmonary stenosis (critical) * Eisenmenger syndrome (reversal of shunt due to pulmonary hypertension).Page Signs and symptoms Presentation includes the following: * Clubbing * The patient assuming a crouching posi ...
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Tetralogy Of Fallot
Tetralogy of Fallot (TOF), formerly known as Steno-Fallot tetralogy, is a congenital heart defect characterized by four specific cardiac defects. Classically, the four defects are: *pulmonary stenosis, which is narrowing of the exit from the right ventricle; * a ventricular septal defect, which is a hole allowing blood to flow between the two ventricles; * right ventricular hypertrophy, which is thickening of the right ventricular muscle; and * an overriding aorta, which is where the aorta expands to allow blood from both ventricles to enter. At birth, children may be asymptomatic or present with many severe symptoms. Later in infancy, there are typically episodes of bluish colour to the skin due to a lack of sufficient oxygenation, known as cyanosis. When affected babies cry or have a bowel movement, they may undergo a "tet spell" where they turn cyanotic, have difficulty breathing, become limp, and occasionally lose consciousness. Other symptoms may include a heart murmur, ...
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Alfred Blalock
Alfred Blalock (April 5, 1899 – September 15, 1964) was an American surgeon most noted for his work on the medical condition of shock as well as Tetralogy of Fallot— commonly known as Blue baby syndrome. He created, with assistance from his research and laboratory assistant Vivien Thomas and pediatric cardiologist Helen Taussig, the Blalock-Thomas-Taussig Shunt, a surgical procedure to relieve the cyanosis from Tetralogy of Fallot. This operation ushered in the modern era of cardiac surgery. He worked at both Vanderbilt University and Johns Hopkins University, where he studied medicine and later served as chief of surgery. He is known as a medical pioneer who won various awards, including Albert Lasker Clinical Medical Research Award. Blalock was also nominated several times for the prestigious Nobel Prize in Medicine. Early life and education Blalock was born in Culloden, Georgia, the son of Martha "Mattie" (Davis) and George Zadock Blalock, a merchant. At the age of 14, ...
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Johns Hopkins Hospital
The Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of the Johns Hopkins School of Medicine, located in Baltimore, Maryland, U.S. It was founded in 1889 using money from a bequest of over $7 million (1873 money, worth 163.9 million dollars in 2021) by city merchant, banker/financier, civic leader and philanthropist Johns Hopkins (1795–1873). Johns Hopkins Hospital and its School of Medicine are considered to be the founding institutions of modern American medicine and the birthplace of numerous famous medical traditions including rounds, residents and house staff. Many medical specialties were formed at the hospital including neurosurgery, by Harvey Cushing and Walter Dandy; cardiac surgery by Alfred Blalock; and child psychiatry, by Leo Kanner. Attached to the hospital is the Johns Hopkins Children’s Center which serves infants, children, teens, and young adults aged 0–21. Johns Hopkins Hospital is widely regarded as one of the world' ...
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Worshipful Company Of Clothworkers
The Worshipful Company of Clothworkers was incorporated by Royal Charter in 1528, formed by the amalgamation of its two predecessor companies, the Fullers (incorporated 1480) and the Shearmen (incorporated 1508). It succeeded to the position of the Shearmen's Company and thus ranks twelfth in the order of precedence of Livery Companies of the City of London. The original craft of the Clothworkers was the finishing of woven woollen cloth: fulling it to mat the fibres and remove the grease, drying it on tenter frames raising the nap with teasels ( Dipsacus) and shearing it to a uniform finish. The Ordinances of The Clothworkers' Company, first issued in 1532 and signed by Sir Thomas More, sought to regulate clothworking, to maintain standards and to protect approved practices. From the later Middle Ages, cloth production gradually moved away from London, a situation exacerbated by the Great Fire of London and the Industrial Revolution of the 18th and 19th centuries. The charitabl ...
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Evan Bedford
Brigadier Davis Evan Bedford (1898–1978) was a British physician and cardiologist. After education at Ipswich School and at Epsom College, D. Evan Bedford entered the Middlesex Hospital Medical School in 1916. In 1918 he became a surgeon sub-lieutenant in the Royal Naval Volunteer Reserve (RNVR) and in 1919 resumed his medical training, graduating in 1921 MB BS (Lond.) and qualifying MRCS, LRCP. After resident appointments at the Middlesex Hospital, he was appointed medical officer in charge of the cardiac wards at the Orpington Hospital belonging to the Ministry of Pensions. In 1925 he graduated MD. At the Orpington Hospital, he was influenced by John Parkinson and in 1925–1926 pursued postgraduate study in France. Returning from France, Bedford in 1926 was appointed Paterson Research Scholar at the London Hospital and assistant physician to the Middlesex Hospital. At the Cardiac Club he became a member in 1928 and was the Club's secretary from 1932 to 1936. In 193 ...
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