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John M. Goldman
John M. Goldman (30 November 1938 – 24 December 2013) was a British haematologist, oncologist and medical researcher. A specialist in chronic myeloid leukaemia, Goldman conducted pioneering research into leukaemia treatment – he was instrumental in the development of bone marrow transplantation as a clinical method, and later in the development of the drug imatinib. He was also a prolific author of scientific papers, was involved with numerous medical charities and had a decades-long surgical career at Hammersmith Hospital, London. Early life and education Goldman was born in London in 1938 to Carl and Berthe Goldman, both Jewish refugees from Nazi Germany. Although he was briefly detained as an enemy alien, Carl Goldman served in the British Army during World War II, and established a successful medical practice in London; he later treated famous individuals such as Elizabeth Taylor and Rex Reed. John Goldman attended the Westminster School and performed in the school choir, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magdalen College, Oxford
Magdalen College (, ) is a constituent college of the University of Oxford. It was founded in 1458 by William of Waynflete. Today, it is the fourth wealthiest college, with a financial endowment of £332.1 million as of 2019 and one of the strongest academically, setting the record for the highest Norrington Score in 2010 and topping the table twice since then. It is home to several of the university's distinguished chairs, including the Agnelli-Serena Professorship, the Sherardian Professorship, and the four Waynflete Professorships. The large, square Magdalen Tower is an Oxford landmark, and it is a tradition, dating to the days of Henry VII, that the college choir sings from the top of it at 6 a.m. on May Morning. The college stands next to the River Cherwell and the University of Oxford Botanic Garden. Within its grounds are a deer park and Addison's Walk. History Foundation Magdalen College was founded in 1458 by William of Waynflete, Bishop of Winchester a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Choir
A choir ( ; also known as a chorale or chorus) is a musical ensemble of singers. Choral music, in turn, is the music written specifically for such an ensemble to perform. Choirs may perform music from the classical music repertoire, which spans from the medieval era to the present, or popular music repertoire. Most choirs are led by a conductor, who leads the performances with arm, hand, and facial gestures. The term ''choir'' is very often applied to groups affiliated with a church (whether or not they actually occupy the quire), whereas a ''chorus'' performs in theatres or concert halls, but this distinction is not rigid. Choirs may sing without instruments, or accompanied by a piano, pipe organ, a small ensemble, or an orchestra. A choir can be a subset of an ensemble; thus one speaks of the "woodwind choir" of an orchestra, or different "choirs" of voices or instruments in a polychoral composition. In typical 18th century to 21st century oratorios and masses, 'choru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Targeted Therapy
Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for cancer, others being hormonal therapy and cytotoxic chemotherapy. As a form of molecular medicine, targeted therapy blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth, rather than by simply interfering with all rapidly dividing cells (e.g. with traditional chemotherapy). Because most agents for targeted therapy are biopharmaceuticals, the term ''biologic therapy'' is sometimes synonymous with ''targeted therapy'' when used in the context of cancer therapy (and thus distinguished from chemotherapy, that is, cytotoxic therapy). However, the modalities can be combined; antibody-drug conjugates combine biologic and cytotoxic mechanisms into one targeted therapy. Another form of targeted therapy involves the use of nanoengineered enzymes to bind to a tumor cell such that the body's natural c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthony Nolan
Anthony Nolan is a UK charity that works in the areas of leukaemia and hematopoietic stem cell transplantation. It manages and recruits donors to the Anthony Nolan Register, which is part of an aligned registry that also includes the ''Welsh Bone Marrow Donor Registry'', NHS Blood and Transplant's ''British Bone Marrow Registry'' and Deutsche KnochenMarkSpenderdatei ( DKMS) UK. This aligned register is known as the ''Anthony Nolan & NHS Stem Cell Registry''. It also carries out research to help make bone marrow transplants more effective. History The charity is named after Anthony Nolan (born 1971–died 1979), who did not suffer from leukaemia but from Wiskott–Aldrich syndrome, a rare inherited blood disorder. It was founded by Anthony's mother Shirley Nolan (1942–2001) in 1974 as the Anthony Nolan Register. Initially based at the Westminster Children's Hospital, it moved to St Mary Abbots Hospital in 1978 and to its present offices, laboratory and research institute in n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Cancer
Tumors of the hematopoietic and lymphoid tissues (American English) or tumours of the haematopoietic and lymphoid tissues (British English) are tumors that affect the blood, bone marrow, lymph, and lymphatic system. Because these tissues are all intimately connected through both the circulatory system and the immune system, a disease affecting one will often affect the others as well, making aplasia, myeloproliferation and lymphoproliferation (and thus the leukemias and the lymphomas) closely related and often overlapping problems. While uncommon in solid tumors, chromosomal translocations are a common cause of these diseases. This commonly leads to a different approach in diagnosis and treatment of hematological malignancies. Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology. In some centers "hematology/oncology" is a single subspecialty of internal medicine while in others they are consid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bone Marrow Transplant
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce additional normal blood cells. It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin). It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient's immune system is usually destroyed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic HSCT. HSCT remains a dangerous procedure with many possible complications; it is reserved for patients with life-threatening diseases. As survival following the procedure has increased, its use has expanded beyond cancer to autoimmune ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Miami
The University of Miami (UM, UMiami, Miami, U of M, and The U) is a private research university in Coral Gables, Florida. , the university enrolled 19,096 students in 12 colleges and schools across nearly 350 academic majors and programs, including the Leonard M. Miller School of Medicine in Miami's Health District, the law school on the main campus, and the Rosenstiel School of Marine and Atmospheric Science on Virginia Key with research facilities in southern Miami-Dade County. The University of Miami offers 138 undergraduate, 140 master's, and 67 doctoral degree programs. Since its founding in 1925, the university has attracted students from all 50 states and 173 foreign countries. With 16,954 faculty and staff as of 2021, the University of Miami is the second largest employer in Miami-Dade County. The university's main campus in Coral Gables spans , has over of buildings, and is located south of Downtown Miami, the heart of the nation's ninth largest and world's 65th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phenome ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haematology
Hematology ( always spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the production of blood and its components, such as blood cells, hemoglobin, blood proteins, bone marrow, platelets, blood vessels, spleen, and the mechanism of coagulation. Such diseases might include hemophilia, blood clots (thrombus), other bleeding disorders, and blood cancers such as leukemia, multiple myeloma, and lymphoma. The laboratory analysis of blood is frequently performed by a medical technologist or medical laboratory scientist. Specialization Physicians specialized in hematology are known as hematologists or haematologists. Their routine work mainly includes the care and treatment of patients with hematological diseases, although some may also work at the hematology laboratory viewing blood films and bone marrow slides under the mi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barbiturates
Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid. They are effective when used medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as well as overdose potential among other possible adverse effects. They have been used recreationally for their anxiolytic and sedative effects, and are thus controlled in most countries due to the risks associated with such use. Barbiturates have largely been replaced by benzodiazepines and nonbenzodiazepines ("Z-drugs") in routine medical practice, particularly in the treatment of anxiety disorders and insomnia, because of the significantly lower risk of overdose, and the lack of an antidote for barbiturate overdose. Despite this, barbiturates are still in use for various purposes: in general anesthesia, epilepsy, treatment of acute migraines or cluster headaches, acute tension headaches, euthanasia, capital punishment, and assisted ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Classics
Classics or classical studies is the study of classical antiquity. In the Western world, classics traditionally refers to the study of Classical Greek and Roman literature and their related original languages, Ancient Greek and Latin. Classics also includes Greco-Roman philosophy, history, archaeology, anthropology, art, mythology and society as secondary subjects. In Western civilization, the study of the Greek and Roman classics was traditionally considered to be the foundation of the humanities, and has, therefore, traditionally been the cornerstone of a typical elite European education. Etymology The word ''classics'' is derived from the Latin adjective '' classicus'', meaning "belonging to the highest class of citizens." The word was originally used to describe the members of the Patricians, the highest class in ancient Rome. By the 2nd century AD the word was used in literary criticism to describe writers of the highest quality. For example, Aulus Gellius, in his ''Att ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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