John J. Tyson
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John J. Tyson
John J. Tyson (born December 12, 1947, in Abington, Pennsylvania) is an American systems biologist and mathematical biologist who serves as University Distinguished Professor of Biology at Virginia Tech, and is the former president of the Society for Mathematical Biology. He is known for his research on biochemical switches in the cell cycle, dynamics of biological networks and on excitable media. Education and career Tyson earned a bachelor's degree in chemistry from Wheaton College, and received his PhD in chemical physics from the University of Chicago. After postdoctoral research at the Max Planck Institute for Biophysical Chemistry, a temporary position teaching mathematics at the University at Buffalo, and another post doctorate at the University of Innsbruck for Biochemistry and Experimental Cancer Research, he joined the Virginia Tech faculty in 1978 and is currently a University Distinguished Professor in Biological Sciences. He was president of the Society for Math ...
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Tyson Portrait (1)
Tyson is a male given name of old French origin meaning 'high-spirited', 'fire'. It is from this that a surname arose 'son of Tyson'. Surname *Alan Tyson (1926–2000), British musicologist *Barbara Tyson (born 1964), Canadian actress *Bill Tyson, Irish writer and producer *Cathy Tyson (born 1965), British actress *Charles Tyson (1885–1964), English footballer *Cicely Tyson (1924–2021), American actress *Donald J. Tyson (1930–2011), American business executive and billionaire *Edward Tyson (1650–1708), English scientist and physician *Frank Tyson (born 1930), English cricketer *Ian Tyson (born 1933), Canadian musician *Isaac Tyson (1792–1861), American mining industrialist *Jacob Tyson (1773–1848), American politician *James Tyson (1819–1898), Australian pastoralist *J. Anthony Tyson (born 1940), American physicist and astronomer *John M. Tyson (born 1953), American judge *June Tyson (1936–1992), American jazz singer *Keith Tyson (born 1969), British artist *Laura T ...
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Journal Of Theoretical Biology
The ''Journal of Theoretical Biology'' is a biweekly peer-reviewed scientific journal covering theoretical biology, as well as mathematical, computational, and statistical aspects of biology. Some research areas covered by the journal include cell biology, evolutionary biology, population genetics, morphogenesis, and immunology. The journal was established in 1961. Its founding editor-in-chief was English biologist James F. Danielli, who remained editor until his death in 1984. The journal is published by Elsevier and, , the editors-in-chief are Denise Kirschner (University of Michigan Medical School), Mark Chaplain (University of St. Andrews), and Akira Sawaki (Aichi Cancer Center, Nagoya). Lewis Wolpert served as editor-in-chief for more than 55 years. According to the ''Journal Citation Reports'' the journal has a 2020 impact factor of 2.691. Notable articles The following are the most highly cited articles (more than 2000 citations at April 2021) that have been published in ...
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Cellular Automatists
Cellular may refer to: *Cellular automaton, a model in discrete mathematics *Cell biology, the evaluation of cells work and more * ''Cellular'' (film), a 2004 movie *Cellular frequencies, assigned to networks operating in cellular RF bands *Cellular manufacturing *Cellular network, cellular radio networks *U.S. Cellular Field, also known as "The Cell", a baseball stadium in Chicago *U.S. Cellular Arena, an arena in Milwaukee, Wisconsin Terms such as cellular organization, cellular structure, cellular system, and so on may refer to: *Cell biology, the evaluation of how cells work and more *Cellular communication networks, systems for allowing communication through mobile phones and other mobile devices *Cellular organizational structures, methods of human organization in social groups *Clandestine cell organizations, entities organized to commit crimes, acts of terror, or other malicious activities See also *Cell (other) Cell most often refers to: * Cell (biology), th ...
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21st-century American Biologists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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National Institute Of General Medical Sciences
The National Institute of General Medical Sciences (NIGMS) supports basic research that increases understanding of biological processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. NIGMS-funded scientists investigate how living systems work at a range of levels, from molecules and cells to tissues and organs, in research organisms, humans, and populations. Additionally, to ensure the vitality and continued productivity of the research enterprise, NIGMS provides leadership in training the next generation of scientists, in enhancing the diversity of the scientific workforce, and in developing research capacity throughout the country. NIGMS is one of the National Institutes of Health (NIH), the principal medical research agency of the Federal Government. NIH is a component of the U.S. Department of Health and Human Services. All NIH Institutes and Centers support basic research that is relevant to the diseases, organ systems, stages of lif ...
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Cell Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such as ...
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Autophagy
Autophagy (or autophagocytosis; from the Ancient Greek , , meaning "self-devouring" and , , meaning "hollow") is the natural, conserved degradation of the cell that removes unnecessary or dysfunctional components through a lysosome-dependent regulated mechanism. It allows the orderly degradation and recycling of cellular components. Although initially characterized as a primordial degradation pathway induced to protect against starvation, it has become increasingly clear that autophagy also plays a major role in the homeostasis of non-starved cells. Defects in autophagy have been linked to various human diseases, including neurodegeneration and cancer, and interest in modulating autophagy as a potential treatment for these diseases has grown rapidly. Four forms of autophagy have been identified: macroautophagy, microautophagy, chaperone-mediated autophagy (CMA), and crinophagy. In macroautophagy (the most thoroughly researched form of autophagy), cytoplasmic components (like mit ...
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Unfolded Protein Response
The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum (ER) stress. It has been found to be conserved between all mammalian species, as well as yeast and worm organisms. The UPR is activated in response to an accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum. In this scenario, the UPR has three aims: initially to restore normal function of the cell by halting protein translation, degrading misfolded proteins, and activating the signalling pathways that lead to increasing the production of molecular chaperones involved in protein folding. If these objectives are not achieved within a certain time span or the disruption is prolonged, the UPR aims towards apoptosis. Sustained overactivation of the UPR has been implicated in prion diseases as well as several other neurodegenerative diseases, and inhibiting the UPR could become a treatment for those diseases. Diseases amenable to UPR inhibition inc ...
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Estrogen Receptor Alpha
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor (mainly found as a chromatin-binding protein) that is activated by the sex hormone estrogen. In humans, ERα is encoded by the gene ''ESR1'' (EStrogen Receptor 1). Structure The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ESR1 mRNA transcripts, which differ primarily in their 5-prime untranslated regions. The translated receptors show less variability. Ligands Agonists Non-selective * Endogenous estrogens (e.g., estradiol, estrone, estriol, estetrol) * Natural estrogens (e.g., conjugated equine estrogens) * Synthetic estrogens (e.g., ethinylestradiol, diethylstilbestrol) Selective Agonists of ERα selective over ERβ include: * Propylp ...
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ...
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