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John Gofman
John William Gofman (21 September 1918 – 15 August 2007) was an American scientist and advocate. He was Professor Emeritus of Molecular and Cell Biology at the University of California at Berkeley. Gofman pioneered the field of clinical lipidology, and in 2007 was honored by the '' Journal of Clinical Lipidology'' with the title of "Father of Clinical Lipidology". With Frank T. Lindgren and other research associates, Gofman discovered and described three major classes of plasma lipoproteins, fat molecules that carry cholesterol in the blood. The team he led at the Donner Laboratory went on to demonstrate the role of lipoproteins in the causation of heart disease. Gofman was instrumental in inducing the health-physics scientific community both to acknowledge the cancer risks of ionizing radiation and to adopt the Linear No-Threshold (LNT) model as a means of estimating actual cancer risks from low-level radiation and as the foundation of the international guidelines for radia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cleveland, Ohio
Cleveland ( ), officially the City of Cleveland, is a city in the U.S. state of Ohio and the county seat of Cuyahoga County. Located in the northeastern part of the state, it is situated along the southern shore of Lake Erie, across the U.S. maritime border with Canada, northeast of Cincinnati, northeast of Columbus, and approximately west of Pennsylvania. The largest city on Lake Erie and one of the major cities of the Great Lakes region, Cleveland ranks as the 54th-largest city in the U.S. with a 2020 population of 372,624. The city anchors both the Greater Cleveland metropolitan statistical area (MSA) and the larger Cleveland–Akron–Canton combined statistical area (CSA). The CSA is the most populous in Ohio and the 17th largest in the country, with a population of 3.63 million in 2020, while the MSA ranks as 34th largest at 2.09 million. Cleveland was founded in 1796 near the mouth of the Cuyahoga River by General Moses Cleaveland, after whom the city was named ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Manhattan Project
The Manhattan Project was a research and development undertaking during World War II that produced the first nuclear weapons. It was led by the United States with the support of the United Kingdom and Canada. From 1942 to 1946, the project was under the direction of Major General Leslie Groves of the United States Army Corps of Engineers, U.S. Army Corps of Engineers. Nuclear physicist Robert Oppenheimer was the director of the Los Alamos Laboratory that designed the actual bombs. The Army component of the project was designated the Manhattan District as its first headquarters were in Manhattan; the placename gradually superseded the official codename, Development of Substitute Materials, for the entire project. Along the way, the project absorbed its earlier British counterpart, Tube Alloys. The Manhattan Project began modestly in 1939, but grew to employ more than 130,000 people and cost nearly US$2 billion (equivalent to about $ billion in ). Over 90 percent of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipoprotein
A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat) molecules in water, as in blood plasma or other extracellular fluids. They consist of a triglyceride and cholesterol center, surrounded by a phospholipid outer shell, with the hydrophilic portions oriented outward toward the surrounding water and lipophilic portions oriented inward toward the lipid center. A special kind of protein, called apolipoprotein, is embedded in the outer shell, both stabilising the complex and giving it a functional identity that determines its role. Many enzymes, transporters, structural proteins, antigens, adhesins, and toxins are lipoproteins. Examples include plasma lipoprotein particles ( HDL, LDL, IDL, VLDL and chylomicrons). Subgroups of these plasma particles are primary drivers or modulators of atherosclerosis. Scope Transmembrane lipoproteins Some transmembrane proteolipids, especially those found in bacteria, are referred ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uranium-232
Uranium-232 () is an isotope of uranium. It has a half-life of around 69 years and is a side product in the thorium cycle. It has been cited as an obstacle to nuclear proliferation using 233U as the fissile material, because the intense gamma radiation emitted by 208Tl (a daughter of 232U, produced relatively quickly) makes the 233U contaminated with it more difficult to handle. Production of 233U (through the neutron irradiation of 232Th) invariably produces small amounts of 232U as an impurity, because of parasitic (n,2n) reactions on uranium-233 itself, or on protactinium-233, or on thorium-232: :232Th (n,γ) 233Th (β−) 233Pa (β−) 233U (n,2n) 232U :232Th (n,γ) 233Th (β−) 233Pa (n,2n) 232Pa (β−) 232U :232Th (n,2n) 231Th (β−) 231Pa (n,γ) 232Pa (β−) 232U Another channel involves neutron capture reaction on small amounts of thorium-230, which is a tiny fraction of natural thorium present due to the decay of uranium-238: :230Th (n,γ) 231Th (β−) 231 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protactinium
Protactinium (formerly protoactinium) is a chemical element with the symbol Pa and atomic number 91. It is a dense, silvery-gray actinide metal which readily reacts with oxygen, water vapor and inorganic acids. It forms various chemical compounds in which protactinium is usually present in the oxidation state +5, but it can also assume +4 and even +3 or +2 states. Concentrations of protactinium in the Earth's crust are typically a few parts per trillion, but may reach up to a few parts per million in some uraninite ore deposits. Because of its scarcity, high radioactivity and high toxicity, there are currently no uses for protactinium outside scientific research, and for this purpose, protactinium is mostly extracted from spent nuclear fuel. The element was first identified in 1913 by Kazimierz Fajans and Oswald Helmuth Göhring and named ''brevium'' because of the short half-life of the specific isotope studied, i.e. protactinium-234. A more stable isotope of protactinium, 231Pa, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
US Atomic Energy Commission
The United States Atomic Energy Commission (AEC) was an agency of the United States government established after World War II by U.S. Congress to foster and control the peacetime development of atomic science and technology. President Harry S. Truman signed the McMahon/Atomic Energy Act on August 1, 1946, transferring the control of atomic energy from military to civilian hands, effective on January 1, 1947. This shift gave the members of the AEC complete control of the plants, laboratories, equipment, and personnel assembled during the war to produce the atomic bomb. An increasing number of critics during the 1960s charged that the AEC's regulations were insufficiently rigorous in several important areas, including radiation protection standards, nuclear reactor safety, plant siting, and environmental protection. By 1974, the AEC's regulatory programs had come under such strong attack that the U.S. Congress decided to abolish the AEC. The AEC was abolished by the Ene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mammography
Mammography (also called mastography) is the process of using low-energy X-rays (usually around 30 kVp) to examine the human breast for diagnosis and screening. The goal of mammography is the early detection of breast cancer, typically through detection of characteristic masses or microcalcifications. As with all X-rays, mammograms use doses of ionizing radiation to create images. These images are then analyzed for abnormal findings. It is usual to employ lower-energy X-rays, typically Mo (K-shell X-ray energies of 17.5 and 19.6 keV) and Rh (20.2 and 22.7 keV) than those used for radiography of bones. Mammography may be 2D or 3D (tomosynthesis), depending on the available equipment and/or purpose of the examination. Ultrasound, ductography, positron emission mammography (PEM), and magnetic resonance imaging (MRI) are adjuncts to mammography. Ultrasound is typically used for further evaluation of masses found on mammography or palpable masses that may or may not be seen on mammogr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chernobyl Disaster
The Chernobyl disaster was a nuclear accident that occurred on 26 April 1986 at the No. 4 reactor in the Chernobyl Nuclear Power Plant, near the city of Pripyat in the north of the Ukrainian SSR in the Soviet Union. It is one of only two nuclear energy accidents rated at seven—the maximum severity—on the International Nuclear Event Scale, the other being the 2011 Fukushima nuclear disaster in Japan. The initial emergency response, together with later decontamination of the environment, involved more than 500,000 personnel and cost an estimated 18 billion roubles—roughly US$68 billion in 2019, adjusted for inflation. The accident occurred during a safety test meant to measure the ability of the steam turbine to power the emergency feedwater pumps of an RBMK-type nuclear reactor in the event of a simultaneous loss of external power and major coolant leak. During a planned decrease of reactor power in preparation for the test, the operators accidentally dropp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Committee For Nuclear Responsibility
The Committee for Nuclear Responsibility was formed as a "political and educational organization to disseminate anti-nuclear views and information to the public". The goals of the organization were a moratorium on nuclear power and the commercialization of alternative energy sources. John Gofman founded the Committee for Nuclear Responsibility in 1971, as a small non-profit, public interest association with four Nobel Laureates on its Board.John W. Gofman, "Irrevy" - An irreverent illustrated view of nuclear power, Committee for Nuclear Responsibility, 1979 These Nobel scientists were Linus Pauling, Harold Urey, George Wald and James D. Watson. Other scientists who were involved included Paul Ehrlich, John Edsall, and Richard E. Bellman. The Board of Directors included Lewis Mumford, Ramsey Clark, Ian MacHarg, and Richard Max McCarthy. Actor Jack Lemmon endorsed the goals of the Committee for Nuclear Responsibility.Jerome Price (1982). ''The Anti-nuclear Movement'', Twayne Publish ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anti-nuclear Movement
The anti-nuclear movement is a social movement that opposes various nuclear technologies. Some direct action groups, environmental movements, and professional organisations have identified themselves with the movement at the local, national, or international level.Fox ButterfieldProfessional Groups Flocking to Antinuclear Drive ''The New York Times'', 27 March 1982. Major anti-nuclear groups include Campaign for Nuclear Disarmament, Friends of the Earth, Greenpeace, International Physicians for the Prevention of Nuclear War, Peace Action, Seneca Women's Encampment for a Future of Peace and Justice and the Nuclear Information and Resource Service. The initial objective of the movement was nuclear disarmament, though since the late 1960s opposition has included the use of nuclear power. Many anti-nuclear groups oppose both nuclear power and nuclear weapons. The formation of green parties in the 1970s and 1980s was often a direct result of anti-nuclear politics.John Barry and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromosomal Abnormalities
A chromosomal abnormality, chromosomal anomaly, chromosomal aberration, chromosomal mutation, or chromosomal disorder, is a missing, extra, or irregular portion of chromosomal DNA. These can occur in the form of numerical abnormalities, where there is an atypical number of chromosomes, or as structural abnormalities, where one or more individual chromosomes are altered. Chromosome mutation was formerly used in a strict sense to mean a change in a chromosomal segment, involving more than one gene. Chromosome anomalies usually occur when there is an error in cell division following meiosis or mitosis. Chromosome abnormalities may be detected or confirmed by comparing an individual's karyotype, or full set of chromosomes, to a typical karyotype for the species via genetic testing. Numerical abnormality An abnormal number of chromosomes is called aneuploidy, and occurs when an individual is either missing a chromosome from a pair (resulting in monosomy) or has more than two chromosome ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Livermore National Laboratory
Lawrence Livermore National Laboratory (LLNL) is a federal research facility in Livermore, California, United States. The lab was originally established as the University of California Radiation Laboratory, Livermore Branch in 1952 in response to the detonation of the first atomic bomb by the Soviet Union during the Cold War. It later became autonomous in 1971 and was designated a national laboratory in 1981. A federally funded research and development center, Lawrence Livermore Lab is primarily funded by the U.S. Department of Energy and it is managed privately and operated by Lawrence Livermore National Security, LLC (a partnership of the University of California), Bechtel, BWX Technologies, AECOM, and Battelle Memorial Institute in affiliation with the Texas A&M University System. In 2012, the laboratory had the synthetic chemical element livermorium (element 116) named after it. Overview LLNL is self-described as a "premier research and development institution for scien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
