John G. Kelton
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John G. Kelton
John G. Kelton, M.D., FRCPC, C.M. is a Canadian hematologist and the past Dean of the McMaster University Medical School and the Dean and Vice-President of the McMaster Faculty of Health Sciences. He completed his 15-year term in June 2016 and is currently the Executive Director of the Michael G. DeGroote Initiative for Innovation in Healthcare at McMaster University in Hamilton. He is an expert on heparin-induced thrombocytopenia. He is known for developing a diagnostic test for heparin-induced thrombocytopenia in 1986. Education Kelton graduated medicine ''cum laude'' from the Schulich School of Medicine and Dentistry at The University of Western Ontario in 1973. Following graduation he trained in internal medicine and hematology at McMaster University and Duke University School of Medicine. In 1977, he was recruited to McMaster. In 2001, he was made the Dean and Vice-President of the faculty of Health Sciences and the Dean of the medical school. Career Kelton is the author of ...
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McMaster University Medical School
The Michael G. DeGroote School of Medicine, known as the McMaster University School of Medicine prior to 2004, is the medical school of McMaster University in Hamilton, Ontario, Canada. It is operated by the McMaster Faculty of Health Sciences. It is one of two medical programs in Canada, along with the University of Calgary, that operates on an accelerated 3-year MD program, instead of the traditional 4-year MD program. Currently, McMaster ranks 11th in the world and 2nd in Canada for medicine according to the Times Higher Education World University Rankings 2021. In 2012, McMaster ranked 14th in the world and 1st in Canada in medicine, according to the Times Higher Education Rankings. The school received 5,605 applications for the Class of 2025, the most applications of any medical school in Canada, and had an acceptance rate of 3.6%. The average cumulative GPA of entering undergraduates in the Class of 2025 was 3.91 and the average MCAT Critical Analysis and Reasoning Skills (C ...
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McMaster Faculty Of Health Sciences
The McMaster Faculty of Health Sciences is one of six faculties at McMaster University in Hamilton, Ontario, Canada. The faculty was established in 1974 to oversee the School of Nursing, the School of Medicine, and Graduate programs in health sciences. Today, the Faculty of Health Sciences oversees 5,000 students, 770 full-time faculty, more than 1,800 part-time faculty, and 28 Canada Research Chairs. The faculty is well known for running the most competitive medical and undergraduate program in Canada. The MD program at McMaster University Medical School receives 5000 applications for 203 positions. The BHSc program at McMaster University receives over 3500 applications for 160 positions annually and was ranked the most competitive undergraduate program in Canada by Yahoo Finance in 2016. The faculty was ranked 25th in the world in the 2015 Times Higher Education World Rankings in the Clinical, Pre-Clinical and Health category. Programs The faculty currently houses the following ...
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Heparin-induced Thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant. HIT predisposes to thrombosis (the abnormal formation of blood clots inside a blood vessel) because platelets release microparticles that activate thrombin, thereby leading to thrombosis. When thrombosis is identified the condition is called heparin-induced thrombocytopenia and thrombosis (HITT). HIT is caused by the formation of abnormal antibodies that activate platelets. If someone receiving heparin develops new or worsening thrombosis, or if the platelet count falls, HIT can be confirmed with specific blood tests. The treatment of HIT requires stopping heparin treatment, and both protection from thrombosis and choice of an agent that will not reduce the platelet count any further. Several alternatives are available for this purpose; mainly used are danaparoid, fondaparinux, argatroban, and bivalirudin. W ...
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Schulich School Of Medicine And Dentistry
The Schulich School of Medicine and Dentistry is the combined medical school and dental school of the University of Western Ontario, a public university in London, Ontario, London, Ontario, Canada The medical education section is one of six in Ontario and one of 17 medical schools in Canada, and the dental education section is one of two in Ontario and one of ten in Canada. History The medical school at the University of Western Ontario was founded under the guidance of Bishop Isaac Hellmuth in 1881. At the time, the university was already at capacity with other departments, so most lectures were to be taken place in a small, five-room cottage. The first lecture was given on October 1, 1882. In 1888, a separate faculty building was opened on the corner of York and Waterloo in London, Ontario. The dental school was founded in 1964 and the first classes started in 1966. The two schools merged in 1997. The school is the seventh oldest in Canada, and the third in Ontario after U ...
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The University Of Western Ontario
The University of Western Ontario (UWO), also known as Western University or Western, is a public research university in London, Ontario, Canada. The main campus is located on of land, surrounded by residential neighbourhoods and the Thames River bisecting the campus's eastern portion. The university operates twelve academic faculties and schools. It is a member of the U15, a group of research-intensive universities in Canada. The university was founded on 7 March 1878 by Bishop Isaac Hellmuth of the Anglican Diocese of Huron as the Western University of London, Ontario. It incorporated Huron College, which had been founded in 1863. The first four faculties were Arts, Divinity, Law and Medicine. The university became non-denominational in 1908. Beginning in 1919, the university had affiliated with several denominational colleges. The university grew substantially in the post-World War II era, and a number of faculties and schools were added. Western is a co-educational univ ...
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McMaster University
McMaster University (McMaster or Mac) is a public research university in Hamilton, Ontario, Canada. The main McMaster campus is on of land near the residential neighbourhoods of Ainslie Wood and Westdale, adjacent to the Royal Botanical Gardens. It operates six academic faculties: the DeGroote School of Business, Engineering, Health Sciences, Humanities, Social Science, and Science. It is a member of the U15, a group of research-intensive universities in Canada. The university bears the name of William McMaster, a prominent Canadian senator and banker who bequeathed C$900,000 to its founding. It was incorporated under the terms of an act of the Legislative Assembly of Ontario in 1887, merging the Toronto Baptist College with Woodstock College. It opened in Toronto in 1890. Inadequate facilities and the gift of land in Hamilton prompted its relocation in 1930. The Baptist Convention of Ontario and Quebec controlled the university until it became a privately chartered, pu ...
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Duke University School Of Medicine
The Duke University School of Medicine, commonly known as Duke Med, is the medical school of Duke University. It is located in the Collegiate Gothic-style West Campus of Duke University in Durham, North Carolina. The School of Medicine, along with the Duke University School of Nursing, Duke University Hospital, Duke Regional Hospital, Duke Children's Hospital, Duke Raleigh Hospital, and other affiliated hospitals, clinics, and laboratories, make up the Duke University Health System. Established in 1925 by James B. Duke, the School of Medicine has earned its reputation as an integral part of one of the world's foremost patient care and biomedical research institutions. Clinical rotations by medical students and residents occur within the Duke University Health System, a fully integrated academic health care system encompassing a tertiary-care hospital and specialty clinics on the Medical Center campus, two community hospitals, a VA hospital, home health and hospice services, a netw ...
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New England Journal Of Medicine
''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. It is among the most prestigious peer-reviewed medical journals as well as the oldest continuously published one. History In September 1811, John Collins Warren, a Boston physician, along with James Jackson, submitted a formal prospectus to establish the ''New England Journal of Medicine and Surgery and Collateral Branches of Science'' as a medical and philosophical journal. Subsequently, the first issue of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' was published in January 1812. The journal was published quarterly. In 1823, another publication, the ''Boston Medical Intelligencer'', appeared under the editorship of Jerome V. C. Smith. The editors of the ''New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science'' purchased the weekly ''Intelligencer'' for $600 in 1 ...
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Unfractionated Heparin
Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Since heparins depend on the activity of antithrombin, they are considered anticoagulants. Specifically it is also used in the treatment of heart attacks and unstable angina. It is given intravenously or by injection under the skin. Other uses for its anticoagulant properties include inside blood specimen test tubes and kidney dialysis machines. Common side effects include bleeding, pain at the injection site, and low blood platelets. Serious side effects include heparin-induced thrombocytopenia. Greater care is needed in those with poor kidney function. Heparin is contraindicated for suspected cases of vaccine-induced pro-thrombotic immune thrombocytopenia (VIPIT) secondary to SARS-CoV-2 vaccination, as heparin may further increase the risk of bleeding in an anti-PF4/heparin complex autoimmune manner, in favor of alternative anticoagulant medications (such as ar ...
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Low Molecular Weight Heparin
Low-molecular-weight heparin (LMWH) is a class of anticoagulant medications. They are used in the prevention of blood clots and treatment of venous thromboembolism (deep vein thrombosis and pulmonary embolism) and in the treatment of myocardial infarction. Heparin is a naturally occurring polysaccharide that inhibits coagulation, the process that leads to thrombosis. Natural heparin consists of molecular chains of varying lengths, or molecular weights. Chains of varying molecular weights, from 5000 to over 40,000 Daltons, make up polydisperse pharmaceutical-grade heparin. LMWHs, in contrast, consist of only short chains of polysaccharide. LMWHs are defined as heparin salts having an average molecular weight of less than 8000 Da and for which at least 60% of all chains have a molecular weight less than 8000 Da. These are obtained by various methods of fractionation or depolymerisation of polymeric heparin. Heparin derived from natural sources, mainly porcine intestine or bovine l ...
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International Society Of Blood Transfusion
The International Society of Blood Transfusion (ISBT) is a scientific society founded in 1935, which promotes the study of blood transfusion and spreads reliable information about the ways in which blood transfusion medicine and science can best serve patients' interests. The society's central office is in Amsterdam, and there are around 1700 members in 97 countries. Currently, the President is Erica Wood. The Society organizes an international congress every other even year and two regional congresses in odd years, one in Europe and one in Asia. ISBT advocates standardisation and harmonisation in the field of blood transfusion. The other major impact on the transfusion community is the classification of various human blood group systems under a common nomenclature. ISBT's coordination also extends to obtaining donors with rare antigens, a process that often involves international searches and a common terminology is critical to that process. History The history of ISBT was des ...
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Order Of Canada
The Order of Canada (french: Ordre du Canada; abbreviated as OC) is a Canadian state order and the second-highest honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the centennial of Canadian Confederation, the three-tiered order was established in 1967 as a fellowship that recognizes the outstanding merit or distinguished service of Canadians who make a major difference to Canada through lifelong contributions in every field of endeavour, as well as the efforts by non-Canadians who have made the world better by their actions. Membership is accorded to those who exemplify the order's Latin motto, , meaning "they desire a better country", a phrase taken from Hebrews 11:16. The three tiers of the order are Companion, Officer, and Member; specific individuals may be given extraordinary membership and deserving non-Canadians may receive honorary appointment into each grade. , the reigning Canadian monarch, is ...
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