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James D. Jamieson
James Douglas Jamieson (January 22, 1934 – October 22, 2018) was a cell biologist and professor at the Yale School of Medicine. His early research in cell biology of pancreatic acinar cells in the lab of George Palade established the function of the Golgi apparatus in secretory protein trafficking. Early life and education Jamieson was born in the small town of Armstrong, British Columbia on January 22, 1934. He attended the University of British Columbia for his undergraduate and medical educations. During medical school, Jamieson took a year off to conduct research, a novel idea for medical students at the time. He owes his interest in research and teaching to this experience with his first mentorsSydney Friedman MD-PhD and Constance Friedman, PhD, who came to UBC in 1950 to found the Department of Anatomy at the new medical school. The focus of the Friedman's research was on hypertension and the role of the kidney and electrolyte balance in the maintenance of blood pressu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Jamieson (other)
James Jamieson may refer to: Sportspeople *James Jamieson (dancer) (1920–1993), Highland dancer *James Jamieson (ice hockey) (1922–1985), hockey player * Jim Jamieson (1943–2018), U.S. golfer * Jimmy Jamieson ( 1890s), Scottish footballer with Everton, Sheffield Wednesday Others *James Jamieson (Australian doctor) (1840–1916), Scottish-born doctor, active in Australia *James Jamieson (New Zealand doctor) (1880–1963), Scottish-born doctor, active in New Zealand * James P. Jamieson (1867–1941), Missouri architect *James Edgar Jamieson (1873–1958), Ontario farmer and political figure *James Jamieson (dentist) James Dalgleish Hamilton Jamieson FRSE FDSE (10 September 1875 – 21 September 1966) was a Scottish dentist and author. Life He was born on 10 September 1875 at 52 Rankeillor Street, a ground floor and basement flat in Edinburgh’s South Si ... (1875–1966), Scottish dentist and author * James D. Jamieson (born 1934), cell biologist See also * James Jamer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philip Siekevitz
Philip Siekevitz (February 25, 1918 – December 5, 2009) was an American cell biologist who spent most of his career at Rockefeller University. He was involved in early studies of protein synthesis and trafficking, established purification techniques to facilitate study of the cell nucleus, worked with Nobel Prize in Physiology or Medicine winner George Palade on cell membrane dynamics, and published extensively on the subject of postsynaptic density. Early life and education Siekevitz was born on February 25, 1918 in Philadelphia to a working-class immigrant family. He spent two years after high school working to save money for his college education, and then began at the Philadelphia College of Pharmacy and Science. He was drafted into the United States Army during his senior year, but deferred his service until after his graduation in 1942. He then served in the army for almost four years, first in a chemical warfare response unit and later as a laboratory technician. Siekevitz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Biologists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale School Of Medicine Faculty
Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and scientific research. Yale is organized into fourteen constituent schools: the original undergraduate coll ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Exocytosis
Exocytosis () is a form of active transport and bulk transport in which a cell transports molecules (e.g., neurotransmitters and proteins) out of the cell ('' exo-'' + ''cytosis''). As an active transport mechanism, exocytosis requires the use of energy to transport material. Exocytosis and its counterpart, endocytosis, are used by all cells because most chemical substances important to them are large polar molecules that cannot pass through the hydrophobic portion of the cell membrane by passive means. Exocytosis is the process by which a large amount of molecules are released; thus it is a form of bulk transport. Exocytosis occurs via secretory portals at the cell plasma membrane called porosomes. Porosomes are permanent cup-shaped lipoprotein structure at the cell plasma membrane, where secretory vesicles transiently dock and fuse to release intra-vesicular contents from the cell. In exocytosis, membrane-bound secretory vesicles are carried to the cell membrane, where they ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Golgi Apparatus
The Golgi apparatus (), also known as the Golgi complex, Golgi body, or simply the Golgi, is an organelle found in most eukaryotic cells. Part of the endomembrane system in the cytoplasm, it packages proteins into membrane-bound vesicles inside the cell before the vesicles are sent to their destination. It resides at the intersection of the secretory, lysosomal, and endocytic pathways. It is of particular importance in processing proteins for secretion, containing a set of glycosylation enzymes that attach various sugar monomers to proteins as the proteins move through the apparatus. It was identified in 1897 by the Italian scientist Camillo Golgi and was named after him in 1898. Discovery Owing to its large size and distinctive structure, the Golgi apparatus was one of the first organelles to be discovered and observed in detail. It was discovered in 1898 by Italian physician Camillo Golgi during an investigation of the nervous system. After first observing it under his ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Rothman
James Edward Rothman (born November 3, 1950) is an American biochemist. He is the Fergus F. Wallace Professor of Biomedical Sciences at Yale University, the Chairman of the Department of Cell Biology at Yale School of Medicine, and the Director of the Nanobiology Institute at the Yale West Campus. Rothman also concurrently serves as adjunct professor of physiology and cellular biophysics at Columbia University and a research professor at the UCL Queen Square Institute of Neurology, University College London. Rothman was awarded the 2013 Nobel Prize in Physiology or Medicine, for his work on vesicle trafficking (shared with Randy Schekman and Thomas C. Südhof). He received many other honors including the King Faisal International Prize in 1996, the Louisa Gross Horwitz Prize from Columbia University and the Albert Lasker Award for Basic Medical Research both in 2002. Personal life He is the son of Martin Rothman, a pediatrician, and Gloria Hartnick. Education Rothman earned ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christian DeDuve
Christian René Marie Joseph, Viscount de Duve (2 October 1917 – 4 May 2013) was a Nobel Prize-winning Belgian cytologist and biochemist. He made serendipitous discoveries of two cell organelles, peroxisome and lysosome, for which he shared the Nobel Prize in Physiology or Medicine in 1974 with Albert Claude and George E. Palade ("for their discoveries concerning the structural and functional organization of the cell"). In addition to peroxisome and lysosome, he invented scientific names such as autophagy, endocytosis, and exocytosis in a single occasion. The son of Belgian refugees during the First World War, de Duve was born in Thames Ditton, Surrey, England. His family returned to Belgium in 1920. He was educated by the Jesuits at Our Lady College, Antwerp, and studied medicine at the Catholic University of Leuven. Upon earning his MD in 1941, he joined research in chemistry, working on insulin and its role in diabetes mellitus. His thesis earned him the highest university ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Keith Porter
Keith Roberts Porter (June 11, 1912 – May 2, 1997) was a Canadian- American cell biologist. He created pioneering biology techniques and research using electron microscopy of cells. Porter also contributed to the development of other experimental methods for cell culture and nuclear transplantation. He was also responsible for naming the endoplasmic reticulum, conducting work on the 9 + 2 microtubule structure in the axoneme of cilia, and coining the term " microtrabecular lattice." In collaborations with other scientists, he contributed to the understanding of scellular structures and concepts such as compartmentalization, flagella, centrioles, fibrin, collagen, T-tubules and sarcoplasmic reticulum. He also introduced microtome cutting Early life and education Keith Porter was born in Yarmouth, Nova Scotia, on June 11, 1912, the son of Aaron and Josephine Roberts Porter. He finished his undergraduate program at Acadia University in 1934, and became a graduate stud ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
