Jaenimonas Drosophilae
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Jaenimonas Drosophilae
''Jaenimonas drosophilae'' is a trypanosomatid parasite of mushroom-feeding flies, first characterized in ''Drosophila neotestacea'' and ''Drosophila falleni''. ''Jaenimonas'' takes up residence in the gut of the fly, and infection leads to reduced fecundity of its fly host. The species is named for John Jaenike, a prominent ecologist and evolutionary biologist whose work on mushroom-feeding flies laid the foundation for studies on mycophagous Drosophila. Of note, ''Jaenimonas'' is the only identified trypanosomatid parasite of a ''Drosophila'' species, and can facilitate study of insect-trypanosome infection dynamics; ''Drosophila'' have powerful genetic tools, and many trypanosomes are vectored by insects and are responsible for diseases such as African sleeping sickness, Chagas disease, and Leishmaniasis. Additionally, ''Crithidia'' trypanosomes are important parasites of Bumblebees implicated in colony collapse disorder. References

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Trypanosoma Cruzi
''Trypanosoma cruzi'' is a species of parasitic euglenoids. Among the protozoa, the trypanosomes characteristically bore tissue in another organism and feed on blood (primarily) and also lymph. This behaviour causes disease or the likelihood of disease that varies with the organism: Chagas disease in humans, dourine and surra in horses, and a brucellosis-like disease in cattle. Parasites need a host body and the haematophagous insect triatomine (descriptions "assassin bug", "cone-nose bug", and "kissing bug") is the major vector in accord with a mechanism of infection. The triatomine likes the nests of vertebrate animals for shelter, where it bites and sucks blood for food. Individual triatomines infected with protozoa from other contact with animals transmit trypanosomes when the triatomine deposits its faeces on the host's skin surface and then bites. Penetration of the infected faeces is further facilitated by the scratching of the bite area by the human or animal host. Life ...
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John Jaenike
John Jaenike is an ecologist and evolutionary biologist, and currently a professor at the University of Rochester New York. Jaenike was an early proponent of the Red Queen Hypothesis, using the idea to explain the maintenance of sex. Jaenike is also known for his extensive work on mushroom-feeding Drosophila and the evolution of their inherited bacterial symbionts ''Wolbachia'' and ''Spiroplasma poulsonii''.Unckless, R. L. and J. Jaenike. 2012. Maintenance of a male-killing Wolbachia in Drosophila innubila by male-killing dependent and male-killing independent mechanisms. Evolution 66: 678-689. In 2015, the trypanosomatid parasite ''Jaenimonas drosophilae'' was named in Jaenike's honour. See also * Drosophila quinaria species group * Mushroom-feeding Drosophila Mushroom-feeding ''Drosophila'' (mycophagous ''Drosophila'') are a subset of ''Drosophila'' flies that have highly specific mushroom-breeding ecologies. Often these flies can tolerate toxic compounds from ''Amanita ...
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Bumblebees
A bumblebee (or bumble bee, bumble-bee, or humble-bee) is any of over 250 species in the genus ''Bombus'', part of Apidae, one of the bee families. This genus is the only extant group in the tribe Bombini, though a few extinct related genera (e.g., ''Calyptapis'') are known from fossils. They are found primarily in higher altitudes or latitudes in the Northern Hemisphere, although they are also found in South America, where a few lowland tropical species have been identified. European bumblebees have also been introduced to New Zealand and Tasmania. Female bumblebees can sting repeatedly, but generally ignore humans and other animals. Most bumblebees are social insects that form colonies with a single queen. The colonies are smaller than those of honey bees, growing to as few as 50 individuals in a nest. Cuckoo bumblebees are brood parasitic and do not make nests or form colonies; their queens aggressively invade the nests of other bumblebee species, kill the resident queen ...
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Crithidia
''Crithidia'' is a genus of trypanosomatid Euglenozoa. They are parasites that exclusively parasitise arthropods, mainly insects. They pass from host to host as cysts in infective faeces and typically, the parasites develop in the digestive tracts of insects and interact with the intestinal epithelium using their flagellum. They display very low host-specificity and a single parasite can infect a large range of invertebrate hosts. At different points in its life-cycle, it passes through amastigote, promastigote, and epimastigote phases; the last is particularly characteristic, and similar stages in other trypanosomes are often called crithidial. The etymology of the genus name ''Crithidia'' derives from the Ancient Greek word (), meaning "small grain of barley". Species * '' Crithidia bombi'' is perhaps the most well documented species and is the most prevalent parasite of bumblebees, including common species like ''Bombus terrestris'', '' Bombus muscorum'', and ''Bombus ho ...
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Leishmaniasis
Leishmaniasis is a wide array of clinical manifestations caused by parasites of the trypanosome genus ''Leishmania''. It is generally spread through the bite of phlebotomine sandflies, ''Phlebotomus'' and ''Lutzomyia'', and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe. The disease can present in three main ways: cutaneous, mucocutaneous, or visceral. The cutaneous form presents with skin ulcers, while the mucocutaneous form presents with ulcers of the skin, mouth, and nose. The visceral form starts with skin ulcers and later presents with fever, low red blood cell count, and enlarged spleen and liver. Infections in humans are caused by more than 20 species of ''Leishmania''. Risk factors include poverty, malnutrition, deforestation, and urbanization. All three types can be diagnosed by seeing the parasites under microscopy. Additionally, visceral disease can be diagnosed by blood tests. Leishmaniasis can be partl ...
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Chagas Disease
Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by ''Trypanosoma cruzi''. It is spread mostly by insects in the subfamily ''Triatominae'', known as "kissing bugs". The symptoms change over the course of the infection. In the early stage, symptoms are typically either not present or mild, and may include fever, swollen lymph nodes, headaches, or swelling at the site of the bite. After four to eight weeks, untreated individuals enter the chronic phase of disease, which in most cases does not result in further symptoms. Up to 45% of people with chronic infections develop heart disease 10–30 years after the initial illness, which can lead to heart failure. Digestive complications, including an enlarged esophagus or an enlarged colon, may also occur in up to 21% of people, and up to 10% of people may experience nerve damage. is commonly spread to humans and other mammals by the bite of a kissing bug. The disease may also be spr ...
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African Sleeping Sickness
African trypanosomiasis, also known as African sleeping sickness or simply sleeping sickness, is an insect-borne parasitic infection of humans and other animals. It is caused by the species '' Trypanosoma brucei''. Humans are infected by two types, ''Trypanosoma brucei gambiense'' (TbG) and ''Trypanosoma brucei rhodesiense'' (TbR). TbG causes over 98% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas. Initially, the first stage of the disease is characterized by fevers, headaches, itchiness, and joint pains, beginning one to three weeks after the bite. Weeks to months later, the second stage begins with confusion, poor coordination, numbness, and trouble sleeping. Diagnosis is by finding the parasite in a blood smear or in the fluid of a lymph node. A lumbar puncture is often needed to tell the difference between first- and second-stage disease. If the disease is not treated quickly it can lead to death. ...
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Drosophila
''Drosophila'' () is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, ''D. melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biological literature. The entire genus, however, contains more than 1,500 species and is very diverse in appearance, be ...
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Mycophagous Drosophila
Mushroom-feeding ''Drosophila'' (mycophagous ''Drosophila'') are a subset of ''Drosophila'' flies that have highly specific mushroom-breeding ecologies. Often these flies can tolerate toxic compounds from ''Amanita'' mushrooms. Species groups * ''Drosophila testacea'' species group * ''Drosophila quinaria'' species group * '' Drosophila bizonata'' species group * Some members of the ''Drosophila obscura'' species group Sequenced genomes or transcriptomes * ''Drosophila guttifera'' * ''Drosophila neotestacea'' * ''Drosophila innubila'' * ''Drosophila falleni'' * '' Drosophila phalerata'' Gallery File: Dneo f3.tif , '' D. neotestacea'' ( Testacea species group) File: Dtestacea male 2-4.tif , '' D. testacea'' ( Testacea species group) File: Dinnubila4.tif , '' D. innubila'' ( Quinaria species group) File:Dguttifera.tif, ''Drosophila guttifera'' ( Quinaria species group) Dphalerata male.tif, '' Drosophila phalerata'' ( Quinaria species group) File:Drosophila falleni infec ...
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Drosophila Falleni
. ''Drosophila falleni'' is a species of fly found in northeastern North America. A mycophagous insect, it is known to feed on the fruit bodies (mushrooms) of several genera of fungi, including ''Agaricus'', ''Amanita'', ''Agrocybe'', ''Boletus'', ''Cortinarius'', ''Pluteus'' ''Grifola'', ''Polyporus'', ''Hypholoma'', ''Russula'', ''Mycena'', ''Stropharia'', and ''Xerula''. The fly can be infested by the parasitic nematode ''Howardula aoronymphium'', which enters the fly larvae when it is feeding on mushrooms. ''Drosophila falleni'' are attracted to mushroom sites by cuing in on specific odourants that are common in rotting mushrooms. However the odourants that attract ''D. falleni'' to mushrooms are different from the odours that attract its nematode parasite ''Howardula aoronymphium''. Infection by ''H. aoronymphium'' alters ''D. falleni'' olfactory preferences, causing infected flies to become more averse to acetate-containing compounds such as ethyl acetate or propyl acetate. ...
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Eukaryota
Eukaryotes () are organisms whose Cell (biology), cells have a cell nucleus, nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the Three-domain system, three domains of life. Bacteria and Archaea (both prokaryotes) make up the other two domains. The eukaryotes are usually now regarded as having emerged in the Archaea or as a sister of the Asgard (archaea), Asgard archaea. This implies that there are only Two-domain system, two domains of life, Bacteria and Archaea, with eukaryotes incorporated among archaea. Eukaryotes represent a small minority of the number of organisms, but, due to their generally much larger size, their collective global biomass (ecology), biomass is estimated to be about equal to that of prokaryotes. Eukaryotes emerged approximately 2.3–1.8 billion years ago, during the Proterozoic eon, likely as Flagellated cell, flagellated phagotrophs. The ...
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Drosophila Neotestacea
''Drosophila neotestacea'' is a member of the ''testacea'' species group of ''Drosophila''. Testacea species are specialist fruit flies that breed on the fruiting bodies of mushrooms. These flies will choose to breed on psychoactive mushrooms such as the Fly Agaric '' Amanita muscaria''. ''Drosophila neotestacea'' can be found in temperate regions of North America, ranging from the north eastern United States to western Canada. Immunity ''Drosophila neotestacea'' and other mushroom-breeding Drosophila have been studied extensively for their interactions with '' Howardula'' nematode parasites, particularly ''Howardula aoronymphium''. Unlike related species, ''D. neotestacea'' is sterilized by ''H. aoronymphium'' infection. The genetic basis of this susceptibility is unknown, and is nematode-dependent. For instance, a related ''Howardula'' species from Japan does not sterilize ''D. neotestacea'', even though the European and North American ''Howardula'' species do. Moreover, t ...
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