Jacques Tréfouël (chemist)
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Jacques Tréfouël (chemist)
Jacques Tréfouël (9 November 1897, Le Raincy – 11 July 1977, Paris) was a French medical chemist. He collaborated closely with his wife, Thérèse Tréfouël, including on the discovery of sulfanilamide. Biography From 1920 to 1928 he worked as an assistant to Ernest Fourneau in the laboratory of medicinal chemistry at the Pasteur Institute. For the next ten years, he served as laboratory chief at the Institute, during which time, he was involved in the synthesis and development of drugs such as stovarsol, orsanine and rhodoquine. In 1935, in collaboration with his wife, chemist Thérèse Tréfouël, and pharmacologists Daniel Bovet and Federico Nitti, he conducted research of prontosil, of which, they demonstrated that only a portion of the substance, named sulphanilamide, was active against streptococcus. The group also showed sulphanilamide's effective action against other types of bacteria ( meningococcus, pneumococcus, gonococcus, Friedlander's bacillus, etc. ...
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Brackets
A bracket is either of two tall fore- or back-facing punctuation marks commonly used to isolate a segment of text or data from its surroundings. Typically deployed in symmetric pairs, an individual bracket may be identified as a 'left' or 'right' bracket or, alternatively, an "opening bracket" or "closing bracket", respectively, depending on the Writing system#Directionality, directionality of the context. Specific forms of the mark include parentheses (also called "rounded brackets"), square brackets, curly brackets (also called 'braces'), and angle brackets (also called 'chevrons'), as well as various less common pairs of symbols. As well as signifying the overall class of punctuation, the word "bracket" is commonly used to refer to a specific form of bracket, which varies from region to region. In most English-speaking countries, an unqualified word "bracket" refers to the parenthesis (round bracket); in the United States, the square bracket. Glossary of mathematical sym ...
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Société De Pathologie Exotique
Lactalis is a French multinational dairy products corporation, owned by the Besnier family and based in Laval, Mayenne, France. The company's former name was Besnier SA. Lactalis is the largest dairy products group in the world, and is the second largest food products group in France, behind Danone. It owns brands such as Parmalat, Président, Siggi's Dairy, Skånemejerier, Rachel's Organic, and Stonyfield Farm. History André Besnier started a small cheesemaking company in 1933 and launched its ''Président'' brand of Camembert in 1968. In 1990, it acquired Group Bridel (2,300 employees, 10 factories, fourth-largest French dairy group) with a presence in 60 countries. In 1992, it acquired United States cheese company Sorrento. In 1999, ''la société Besnier'' became ''le groupe Lactalis'' owned by Belgian holding company BSA International SA. In 2006, they bought Italian group Galbani, and in 2008, bought Swiss cheesemaker Baer. They bought Italian group Parmalat in a 2 ...
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French Pharmacologists
French (french: français(e), link=no) may refer to: * Something of, from, or related to France ** French language, which originated in France, and its various dialects and accents ** French people, a nation and ethnic group identified with France ** French cuisine French cuisine () is the cooking traditions and practices from France. It has been influenced over the centuries by the many surrounding cultures of Spain, Italy, Switzerland, Germany and Belgium, in addition to the food traditions of the re ..., cooking traditions and practices Fortnite French places Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * Française (film), ''Française'' (film), 2008 * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a particular type of military jacket or tunic used in the Russian Empire and ...
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1977 Deaths
Events January * January 8 – Three bombs explode in Moscow within 37 minutes, killing seven. The bombings are attributed to an Armenian separatist group. * January 10 – Mount Nyiragongo erupts in eastern Zaire (now the Democratic Republic of the Congo). * January 17 ** 49 marines from the and are killed as a result of a collision in Barcelona harbour, Spain. * January 18 ** Scientists identify a previously unknown bacterium as the cause of the mysterious Legionnaires' disease. ** Australia's worst railway disaster at Granville, a suburb of Sydney, leaves 83 people dead. ** SFR Yugoslavia Prime minister Džemal Bijedić, his wife and 6 others are killed in a plane crash in Bosnia and Herzegovina. * January 19 – An Ejército del Aire CASA C-207C Azor (registration T.7-15) plane crashes into the side of a mountain near Chiva, on approach to Valencia Airport in Spain, killing all 11 people on board. * January 20 – Jimmy Carter is sworn in as the 39th Preside ...
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1897 Births
Events January–March * January 2 – The International Alpha Omicron Pi sorority is founded, in New York City. * January 4 – A British force is ambushed by Chief Ologbosere, son-in-law of the ruler. This leads to a punitive expedition against Benin. * January 7 – A cyclone destroys Darwin, Australia. * January 8 – Lady Flora Shaw, future wife of Governor General Lord Lugard, officially proposes the name "Nigeria" in a newspaper contest, to be given to the British Niger Coast Protectorate. * January 22 – In this date's issue of the journal ''Engineering'', the word ''computer'' is first used to refer to a mechanical calculation device. * January 23 – Elva Zona Heaster is found dead in Greenbrier County, West Virginia. The resulting murder trial of her husband is perhaps the only capital case in United States history, where spectral evidence helps secure a conviction. * January 31 – The Czechoslovak Trade Union Association is f ...
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Arsenic
Arsenic is a chemical element with the symbol As and atomic number 33. Arsenic occurs in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal. Arsenic is a metalloid. It has various allotropes, but only the gray form, which has a metallic appearance, is important to industry. The primary use of arsenic is in alloys of lead (for example, in car batteries and ammunition). Arsenic is a common n-type dopant in semiconductor electronic devices. It is also a component of the III-V compound semiconductor gallium arsenide. Arsenic and its compounds, especially the trioxide, are used in the production of pesticides, treated wood products, herbicides, and insecticides. These applications are declining with the increasing recognition of the toxicity of arsenic and its compounds. A few species of bacteria are able to use arsenic compounds as respiratory metabolites. Trace quantities of arsenic are an essential dietary element in rats, ham ...
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Pentavalents
In chemistry, the valence (US spelling) or valency (British spelling) of an element is the measure of its combining capacity with other atoms when it forms chemical compounds or molecules. Description The combining capacity, or affinity of an atom of a given element is determined by the number of hydrogen atoms that it combines with. In methane, carbon has a valence of 4; in ammonia, nitrogen has a valence of 3; in water, oxygen has a valence of 2; and in hydrogen chloride, chlorine has a valence of 1. Chlorine, as it has a valence of one, can be substituted for hydrogen. Phosphorus has a valence of 5 in phosphorus pentachloride, . Valence diagrams of a compound represent the connectivity of the elements, with lines drawn between two elements, sometimes called bonds, representing a saturated valency for each element. The two tables below show some examples of different compounds, their valence diagrams, and the valences for each element of the compound. Modern definitions ...
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Sulfamide
Sulfamide (IUPAC name: sulfuric diamide) is an organosulfur compound with the chemical formula and structure . Sulfamide is produced by the reaction of sulfuryl chloride with ammonia. Sulfamide was first prepared in 1838 by the French chemist Henri Victor Regnault. Sulfamide functional group In organic chemistry, the term ''sulfamide'' may also refer to the functional group which consists of at least one organic group attached to a nitrogen atom of sulfamide. Symmetric sulfamides can be prepared directly from amines, sulfur dioxide gas and an oxidant: : In this example, the reactants are aniline, triethylamine (, Et = ethyl group), and iodine. Sulfur dioxide is believed to be activated through a series of intermediates: , and . The sulfamide functional group is an increasingly common structural feature used in medicinal chemistry. See also * Sulfamic acid Sulfamic acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, sulphamic acid and su ...
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Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spread by h ...
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Académie Des Sciences
The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French scientific research. It was at the forefront of scientific developments in Europe in the 17th and 18th centuries, and is one of the earliest Academies of Sciences. Currently headed by Patrick Flandrin (President of the Academy), it is one of the five Academies of the Institut de France. History The Academy of Sciences traces its origin to Colbert's plan to create a general academy. He chose a small group of scholars who met on 22 December 1666 in the King's library, near the present-day Bibliothèque Nationals, and thereafter held twice-weekly working meetings there in the two rooms assigned to the group. The first 30 years of the Academy's existence were relatively informal, since no statutes had as yet been laid down for the institution. In contrast to its British ...
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Académie De Médecine
An academy ( Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, '' Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulatio ...
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