Jacqueline Noonan
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Jacqueline Noonan
Jacqueline Anne Noonan (October 28, 1928 – July 23, 2020) was an American pediatric cardiologist best known for her characterization of a genetic disorder now called Noonan syndrome. She was also the original describer of hypoplastic left heart syndrome. Biography Noonan was born October 28, 1928 in Burlington, Vermont, United States the daughter of Francis and Eugenia Noonan. She had three sisters, Beverly, Joan, and Joyce. She studied chemistry at Albertus Magnus College, medicine at the University of Vermont, and became certified in her field in Boston in 1956. She subsequently began work at the University of Iowa. As their first pediatric cardiologist, she noticed that children with a rare type of heart defect called pulmonary valve stenosis often had a characteristic physical appearance with short stature, webbed neck, wide-spaced eyes, and low-set ears. She presented her first paper on the subject in 1963, and after several more papers and recognition, the condition was ...
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Burlington, Vermont
Burlington is the most populous city in the U.S. state of Vermont and the seat of Chittenden County. It is located south of the Canada–United States border and south of Montreal. As of the 2020 U.S. census, the population was 44,743. It ranks as the least populous city in the United States to also be the most populous city in its state. A regional college town, Burlington is home to Champlain College and the University of Vermont (UVM). Vermont's largest hospital, the UVM Medical Center, is within the city limits. The City of Burlington owns Vermont's largest airport, the Burlington International Airport, located in neighboring South Burlington. In 2015, Burlington became the first city in the U.S. to run entirely on renewable energy. History Early history to early 20th century Two theories have been put forward regarding the origin of Burlington's name. The first is that it was named after Richard Boyle, 3rd Earl of Burlington, and the second is that the name ...
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Noonan Syndrome
Noonan syndrome (NS) is a genetic disorder that may present with mildly unusual facial features, short height, congenital heart disease, bleeding problems, and skeletal malformations. Facial features include widely spaced eyes, light-colored eyes, low-set ears, a short neck, and a small lower jaw. Heart problems may include pulmonary valve stenosis. The breast bone may either protrude or be sunken, while the spine may be abnormally curved. Intelligence in the syndrome is often normal. Complications of NS can include leukemia. A number of genetic mutations can result in Noonan syndrome. The condition may be inherited from a person's parents as an autosomal dominant condition or occur as a new mutation. Noonan syndrome is a type of RASopathy, the underlying mechanism for which involves overactivation within the RAS/MAPK cell signaling pathway. The diagnosis may be suspected based on symptoms, medical imaging, and blood tests. Confirmation may be achieved with genetic tes ...
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American Women Physicians
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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Kentucky Women In Health Professions
Kentucky ( , ), officially the Commonwealth of Kentucky, is a state in the Southeastern region of the United States and one of the states of the Upper South. It borders Illinois, Indiana, and Ohio to the north; West Virginia and Virginia to the east; Tennessee to the south; and Missouri to the west. Its northern border is defined by the Ohio River. Its capital is Frankfort, and its two largest cities are Louisville and Lexington. Its population was approximately 4.5 million in 2020. Kentucky was admitted into the Union as the 15th state on June 1, 1792, splitting from Virginia in the process. It is known as the "Bluegrass State", a nickname based on Kentucky bluegrass, a species of green grass found in many of its pastures, which has supported the thoroughbred horse industry in the center of the state. Historically, it was known for excellent farming conditions for this reason and the development of large tobacco plantations akin to those in Virginia and North Carolina in ...
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