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Journal Of Endocrinology
The ''Journal of Endocrinology'' is a monthly peer-reviewed scientific journal that publishes original research articles, reviews and commentaries. Its focus is on endocrine physiology and metabolism, including hormone secretion, hormone action, and biological effects. The journal considers basic and translational studies at the organ and whole organism level. The journal is published by Bioscientifica on behalf of the Society for Endocrinology. It is also an official journal of the European Society of Endocrinology and the Endocrine Society of Australia. The co-editors-in-chief are Martin Haluzík (Charles University) and Colin Farquharson (University of Edinburgh). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 4.286. History The journal was conceived by Sir Charles Dodds Bart FRS (the founding editor-in-chief), Sir Frank Young FRS, Sir Alan Parkes FRS, and Lord Solly Zuckerman OM KCB FRS in 1937. The first issue was published in 1939 ...
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Endocrinology
Endocrinology (from '' endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep, digestion, respiration, excretion, mood, stress, lactation, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology. The endocrine system consists of several glands, all in different parts of the body, that secrete hormones directly into the blood rather than into a duct system. Therefore, endocrine glands are regarded as ductless glands. Hormones have many different functions and modes of action; one hormone may have several effects on different target organs, and, conversely, one target orga ...
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University Of Edinburgh
The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1582 and officially opened in 1583, it is one of Scotland's four ancient universities and the sixth-oldest university in continuous operation in the English-speaking world. The university played an important role in Edinburgh becoming a chief intellectual centre during the Scottish Enlightenment and contributed to the city being nicknamed the " Athens of the North." Edinburgh is ranked among the top universities in the United Kingdom and the world. Edinburgh is a member of several associations of research-intensive universities, including the Coimbra Group, League of European Research Universities, Russell Group, Una Europa, and Universitas 21. In the fiscal year ending 31 July 2021, it had a total income of £1.176 billion, of ...
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Journal Of Molecular Endocrinology
The ''Journal of Molecular Endocrinology'' is a peer-reviewed scientific journal published eight times per year. Its focus is on molecular and cellular mechanisms in endocrinology, including gene regulation, cell biology, signalling, mutations and transgenesis. The journal is published by Bioscientifica on behalf of the Society for Endocrinology. It is also an official journal of the European Society of Endocrinology and the Endocrine Society of Australia. The co-editors-in-chief are Martin Haluzík (Charles University in Prague) and Colin Farquharson (University of Edinburgh). History The ''Journal of Molecular Endocrinology'' was founded in 1988 in response to the rapid increase in research output in the areas of molecular and genetic endocrinology that had occurred as a result of technological advancements of the 1970s and 1980s, such as the development of recombinant DNA techniques, DNA sequencing and the invention of polymerase chain reaction (PCR). The founding edito ...
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Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation; Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications ...
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DNA Sequencing
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics. Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers, characterize antibody repertoire, and can be used to guide patient treatment. Having a quick way to sequence DNA allows for faster and more individualized medical care to be administered, and for more organisms to be identified and cataloged. The rapid speed of sequencing attained with modern D ...
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Recombinant DNA
Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) that bring together genetic material from multiple sources, creating sequences that would not otherwise be found in the genome. Recombinant DNA is the general name for a piece of DNA that has been created by combining at least two fragments from two different sources. Recombinant DNA is possible because DNA molecules from all organisms share the same chemical structure, and differ only in the nucleotide sequence within that identical overall structure. Recombinant DNA molecules are sometimes called chimeric DNA, because they can be made of material from two different species, like the mythical chimera. R-DNA technology uses palindromic sequences and leads to the production of sticky and blunt ends. The DNA sequences used in the construction of recombinant DNA molecules can originate from any species. For example, plant DNA may be joined to bacter ...
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Editorial Board
The editorial board is a group of experts, usually at a publication, who dictate the tone and direction the publication's editorial policy will take. Mass media At a newspaper, the editorial board usually consists of the editorial page editor, and editorial writers. Some newspapers include other personnel as well. Editorial boards for magazines may include experts in the subject area that the magazine focuses on, and larger magazines may have several editorial boards grouped by subject. An executive editorial board may oversee these subject boards, and usually includes the executive editor and representatives from the subject focus boards. Editorial boards meet on a regular basis to discuss the latest news and opinion trends and discuss what the newspaper should say on a range of issues. They will then decide who will write what editorials and for what day. When such an editorial appears in a newspaper, it is considered the institutional opinion of that newspaper. At some newspap ...
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Scholarly Paper
Academic publishing is the subfield of publishing which distributes academic research and scholarship. Most academic work is published in academic journal articles, books or theses. The part of academic written output that is not formally published but merely printed up or posted on the Internet is often called "grey literature". Most scientific and scholarly journals, and many academic and scholarly books, though not all, are based on some form of peer review or editorial refereeing to qualify texts for publication. Peer review quality and selectivity standards vary greatly from journal to journal, publisher to publisher, and field to field. Most established academic disciplines have their own journals and other outlets for publication, although many academic journals are somewhat interdisciplinary, and publish work from several distinct fields or subfields. There is also a tendency for existing journals to divide into specialized sections as the field itself becomes more sp ...
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Solly Zuckerman, Baron Zuckerman
Solomon "Solly" Zuckerman, Baron Zuckerman (30 May 1904 – 1 April 1993) was a British public servant, zoologist and operational research pioneer. He is best remembered as a scientific advisor to the Allies on bombing strategy in the Second World War, for his work to advance the cause of nuclear non-proliferation, and for his role in bringing attention to global economic issues.King, Stev"From boffin to baron", ''The Spectator'' (9 June 2001) Early life and education Solomon Zuckerman was born in Cape Town in the British Cape Colony (modern-day South Africa) on 30 May 1904, the second child and eldest son of Moses and Rebecca Zuckerman (née Glaser). Both his parents were the children of Jewish immigrants from the Russian Empire. He was educated at the South African College School. After studying medicine at the University of Cape Town and later attending Yale University, he went to London in 1926 to complete his studies at University College Hospital Medical School. He began ...
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Frank George Young
Sir Frank George Young FRS (25 March 1908 – 20 September 1988) was a distinguished biochemist, noted for his work on diabetes, and the first Master of Darwin College, Cambridge. Early life Young was born in London and educated at Alleyn's School, Dulwich and University College, London where he graduated in chemistry and physics in 1929. After graduating, he remained at UCL to do postgraduate research in the field of biochemistry. Career Academic career As a research fellow Young studied diabetes at the University of Aberdeen and the University of Toronto. At the age of 34 he was awarded his first chair when appointed in 1942 as the Professor of Biochemistry at St Thomas's Hospital Medical School, University of London. Thereafter his advancement was rapid, becoming professor of biochemistry at UCL in 1945 and then, in 1949, being elected as the third Sir William Dunn Professor of Biochemistry at Cambridge University, a post he was to hold for the ensuing 26 years. His Cambridge ...
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Charles Dodds
Sir Edward Charles Dodds, 1st Baronet (13 October 1899 – 16 December 1973) was a British biochemist. Personal life He was born in Liverpool in 1899, the only child of Ralph Edward Dodds, a shoe retailer, and Jane (née Pack) Dodds. The family shortly moved to Leeds, then to Darlington and then to Chesham, Bucks, where he attended Harrow County School. From there he entered the Middlesex Hospital Medical School in London in 1916, spent one year in the army in 1917, and qualified MRCS and LRCP in 1921. He died at Sussex Square in Paddington, London on 16 December 1973. Career In 1924 he was appointed to the new Chair of Biochemistry at the University of London which was started in the Bland Sutton Institute of Pathology at the Middlesex. Three years later, he was appointed Director of the recently completed Courtauld Institute of Biochemistry and retained these two appointments until his retirement forty years later. His scientific interests were wide and varied; he had a conti ...
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