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John C. Sheehan
John Clark Sheehan (September 23, 1915 – March 21, 1992) was an American organic chemist whose work on synthetic penicillin led to tailor-made forms of the drug. After nine years of hard work at the Massachusetts Institute of Technology (M.I.T.), he became the first to discover a practical method for synthesizing penicillin V. While achieving total synthesis, Sheehan also produced an intermediate compound, 6-aminopenicillanic acid, which turned out to be the foundation of hundreds of kinds of synthetic penicillin. Dr. Sheehan's research on synthetic penicillin paved the way for the development of customized forms of the lifesaving antibiotic that target specific bacteria. Over the four decades he worked at M.I.T., Sheehan came to hold over 30 patents, including the invention of ampicillin, a commonly used semi-synthetic penicillin that is taken orally rather than by injection. His research covered not only penicillin, but also peptides, other antibiotics, alkaloids, and steroid ...
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Battle Creek, Michigan
Battle Creek is a city in the U.S. state of Michigan, in northwest Calhoun County, Michigan, Calhoun County, at the confluence of the Kalamazoo River, Kalamazoo and Battle Creek River, Battle Creek rivers. It is the principal city of the Battle Creek, Michigan Metropolitan Statistical Area (MSA), which encompasses all of Calhoun County. As of the 2020 United States census, 2020 census, the city had a total population of 52,731. Nicknamed "Cereal City", it is best known as the home of the Kellogg's, Kellogg Company and the founding city of Post Consumer Brands. Toponym One local legend says Battle Creek was named after an encounter between a Surveyor General of the Northwest Territory, federal government land survey party led by Colonel John Mullett and two Potawatomi in March 1824. The two Potawatomi had approached the camp asking for food because they were hungry as the US Army was late delivering supplies promised to them under the 1821 Treaty of Chicago. After a protracted disc ...
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Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic relationsh ...
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San Francisco
San Francisco (; Spanish language, Spanish for "Francis of Assisi, Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the List of California cities by population, fourth most populous in California and List of United States cities by population, 17th most populous in the United States, with 815,201 residents as of 2021. It covers a land area of , at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. city after New York City, and the County statistics of the United States, fifth most densely populated U.S. county, behind only four of the five New York City boroughs. Among the 91 U.S. cities proper with over 250,000 residents, San Francisco was ranked first by per capita income (at $160,749) and sixth by aggregate income as of 2021. Colloquial nicknames for San Francisco include ''SF'', ''San Fran'', ''The '', ''Frisco'', and '' ...
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The Battle Creek Enquirer
The ''Battle Creek Enquirer'' is a daily newspaper in Battle Creek, Michigan. The newspaper, owned by the Gannett, is the only daily paper serving Calhoun County, Michigan Calhoun County is a county in the U.S. state of Michigan. As of the 2020 Census, the population was 134,310. The county seat is Marshall. The county was established on October 19, 1829, and named after John C. Calhoun, who was at the time Vice ... and parts of four neighboring counties. In the late 1950s, the ''Enquirer'' sponsored the George Award, which was meant to recognize civic-minded citizens. References External links * Calhoun County, Michigan Gannett publications Newspapers published in Michigan {{michigan-newspaper-stub ...
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National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ...
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John Dombrowski Roberts
John Dombrowski Roberts (June 8, 1918 – October 29, 2016) was an American chemist. He made contributions to the integration of physical chemistry, spectroscopy, and organic chemistry for the understanding of chemical reaction rates. Another characteristic of Roberts' work was the early use of NMR, focusing on the concept of spin coupling. Career Roberts received both a B.A. (1941) and Ph.D. (1944) from the University of California, Los Angeles, working under Professor William Gould Young. He held several positions at the California Institute of Technology, including division chairman of chemistry and chemical engineering from 1963 to 1968, dean of the faculty and provost from 1980 to 1983 and Institute Professor of chemistry, emeritus (1988–2016) in the Division of Chemistry and Chemical Engineering. He is credited with bringing the first female graduate student, Dorothy Semenow, to Caltech when he moved from MIT. He was a consultant for DuPont Central Research (1950†...
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Catholic
The Catholic Church, also known as the Roman Catholic Church, is the largest Christian church, with 1.3 billion baptized Catholics worldwide . It is among the world's oldest and largest international institutions, and has played a prominent role in the history and development of Western civilization.O'Collins, p. v (preface). The church consists of 24 ''sui iuris'' churches, including the Latin Church and 23 Eastern Catholic Churches, which comprise almost 3,500 dioceses and eparchies located around the world. The pope, who is the bishop of Rome, is the chief pastor of the church. The bishopric of Rome, known as the Holy See, is the central governing authority of the church. The administrative body of the Holy See, the Roman Curia, has its principal offices in Vatican City, a small enclave of the Italian city of Rome, of which the pope is head of state. The core beliefs of Catholicism are found in the Nicene Creed. The Catholic Church teaches that it is th ...
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Yankee
The term ''Yankee'' and its contracted form ''Yank'' have several interrelated meanings, all referring to people from the United States. Its various senses depend on the context, and may refer to New Englanders, residents of the Northern United States, or Americans in general. According to the ''Oxford English Dictionary'', it is "a nickname for a native or inhabitant of New England, or, more widely, of the northern States generally". Outside the United States, ''Yank'' is used informally to refer to an American person or thing. It has been especially popular in the United Kingdom, Ireland, Canada, South Africa, Australia, and New Zealand where it may be used variously with uncomplimentary overtones or cordially. In the Southern United States, ''Yankee'' is a derisive term which refers to all Northerners, and during the American Civil War was applied by Confederates to soldiers of the Union army in general. Elsewhere in the United States, it largely refers to people from the Nort ...
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Irish People
The Irish ( ga, Muintir na hÉireann or ''Na hÉireannaigh'') are an ethnic group and nation native to the island of Ireland, who share a common history and culture. There have been humans in Ireland for about 33,000 years, and it has been continually inhabited for more than 10,000 years (see Prehistoric Ireland). For most of Ireland's recorded history, the Irish have been primarily a Gaelic people (see Gaelic Ireland). From the 9th century, small numbers of Vikings settled in Ireland, becoming the Norse-Gaels. Anglo-Normans also conquered parts of Ireland in the 12th century, while England's 16th/17th century conquest and colonisation of Ireland brought many English and Lowland Scots to parts of the island, especially the north. Today, Ireland is made up of the Republic of Ireland (officially called Ireland) and Northern Ireland (a part of the United Kingdom). The people of Northern Ireland hold various national identities including British, Irish, Northern Irish or som ...
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Steroids
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and as signaling molecules. Hundreds of steroids are found in plants, animals and fungi. All steroids are manufactured in cells from the sterols lanosterol (opisthokonts) or cycloartenol (plants). Lanosterol and cycloartenol are derived from the cyclization of the triterpene squalene. The steroid core structure is typically composed of seventeen carbon atoms, bonded in four " fused" rings: three six-member cyclohexane rings (rings A, B and C in the first illustration) and one five-member cyclopentane ring (the D ring). Steroids vary by the functional groups attached to this four-ring core and by the oxidation state of the rings. Sterols are forms of steroids with a hydroxy group at position three and a skeleton derived from cholestane. '' ...
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Alkaloids
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , ,

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Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antisep ...
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