Isadore Sharp
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Isadore Sharp
Isadore "Issy" Sharp, (born October 8, 1931) is a Canadian hotelier and writer. He is founder and chairman of Four Seasons Hotels and Resorts. Early life and education Sharp was born in Toronto, the son of Polish Jewish immigrants. His father, Max, a devout Torah scholar, was a Polish Jew who emigrated from Poland to Palestine in 1920, and finally to Toronto five years later. He worked as a plasterer until his family began to grow with the arrival of Issy and three daughters. His father's expertise was in home renovation and he often renovated homes and resold them for a profit as a real estate investor. During the summers, Sharp would obtain experience in the construction business by working for his father. He excelled in sports during his high school years. In 1952, he graduated with high marks from Ryerson Institute of Technology (now Toronto Metropolitan University) with a diploma in architectural technology.
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Toronto
Toronto ( ; or ) is the capital city of the Canadian province of Ontario. With a recorded population of 2,794,356 in 2021, it is the most populous city in Canada and the fourth most populous city in North America. The city is the anchor of the Golden Horseshoe, an urban agglomeration of 9,765,188 people (as of 2021) surrounding the western end of Lake Ontario, while the Greater Toronto Area proper had a 2021 population of 6,712,341. Toronto is an international centre of business, finance, arts, sports and culture, and is recognized as one of the most multicultural and cosmopolitan cities in the world. Indigenous peoples have travelled through and inhabited the Toronto area, located on a broad sloping plateau interspersed with rivers, deep ravines, and urban forest, for more than 10,000 years. After the broadly disputed Toronto Purchase, when the Mississauga surrendered the area to the British Crown, the British established the town of York in 1793 and later designat ...
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Cascade Investments LLC
Cascade Investment, L.L.C. is an American holding company and private investment firm headquartered in Kirkland, Washington, United States. It is controlled by Bill Gates, and managed by Michael Larson. More than half of Gates's fortune is held in assets outside his holding of Microsoft shares. Cascade is the successor company to Dominion Income Management, the former investment vehicle for Gates's holdings, which was managed by convicted felon Andrew Evans. Larson controls Bill and Melinda Gates Investments as Chief Investment Officer, and as such manages Gates's personal wealth through Cascade, "as well as handling the Bill & Melinda Gates Foundation Trust endowment." Cascade "does not like to call itself" a family office and Bill and Melinda Gates Investments "does not label itself as a family office." Larson accrued over the twenty years from 1995 an 11% compound annual return Compound annual growth rate (CAGR) is a business and investing specific term for the geometric ...
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Jewish Museum Of Canada
The Jewish Museum of Canada is a proposed museum to be built in Toronto, Ontario, Canada by a partnership of the family of Rosalie and Isadore Sharp, founder of the Four Seasons Hotels and Resorts, and the United Jewish Appeal Federation of Greater Toronto. The Sharp family has pledged $20 million towards the project, towards a total fundraising goal of $150 million. The museum is to feature three themed galleries with artifact and multimedia-based interactives and three immersive environments entitled: Jewish Experience, Jewish Life in Canada and The Neuberger Holocaust Education Centre. The proposal, which was announced in September 2014, has been indefinitely shelved due to the United Jewish Appeal prioritizing other fundraising projects while the University of Toronto, which had been a partner in the project, wished to proceed immediately with developing the cultural centre that the museum was to be a part. Isadore Sharp, who initiated the project, said in January 2016 that: "T ...
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Hebrew University Of Jerusalem
The Hebrew University of Jerusalem (HUJI; he, הַאוּנִיבֶרְסִיטָה הַעִבְרִית בִּירוּשָׁלַיִם) is a public research university based in Jerusalem, Israel. Co-founded by Albert Einstein and Dr. Chaim Weizmann in July 1918, the public university officially opened in April 1925. It is the second-oldest Israeli university, having been founded 30 years before the establishment of the State of Israel but six years after the older Technion university. The HUJI has three campuses in Jerusalem and one in Rehovot. The world's largest library for Jewish studies—the National Library of Israel—is located on its Edmond J. Safra campus in the Givat Ram neighbourhood of Jerusalem. The university has five affiliated teaching hospitals (including the Hadassah Medical Center), seven faculties, more than 100 research centers, and 315 academic departments. , one-third of all the doctoral candidates in Israel were studying at the HUJI. Among its first ...
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Mount Sinai Hospital, Toronto
Mount Sinai Hospital (MSH) is a hospital in Toronto, Ontario, Canada. Mount Sinai is part of Sinai Health. Sinai Health was formed through the voluntary amalgamation of Mount Sinai Hospital (including the Lunenfeld-Tanenbaum Research Institute) and Hennick Bridgepoint Hospital on January 22, 2015. Mount Sinai is linked by bridges and tunnels to three adjacent hospitals of the University Health Network (Toronto General Hospital, Toronto Rehabilitation Institute, and Princess Margaret Cancer Centre). During the 2005 annual charity, the hospital reported to the Canada Revenue Agency as having assets of roughly C$ 520 million. In the 2019-2020 fiscal year there were nearly 29,000 inpatient stays and 59,700 emergency department visits for Mount Sinai Hospital. The average length of stay for inpatients was 4.4 days. Mount Sinai Hospital has existed in Toronto since 1923 under various names; it has occupied its present site on University Avenue since 1953. In the fiscal year ending M ...
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Ontario College Of Art & Design
Ontario College of Art & Design University, commonly known as OCAD University or OCAD, is a public art university located in Toronto, Ontario, Canada. The university's main campus is spread throughout several buildings and facilities within downtown Toronto. The university is a co-educational institution which operates three academic faculties, the Faculty of Art, the Faculty of Arts and Science, and the Faculty of Design. The university also provides continuing education services through its School of Continuing Studies. Established in 1876 as the Ontario School of Art by the Ontario Society of Artists, the institution was the first school opened in Canada dedicated to art education. The institution was renamed twice in 1886 and 1890 before it was granted a provincial charter and renamed the Ontario College of Art (OCA) in 1912. The institution was known as the OCA until 1996 when it was renamed the ''Ontario College of Art and Design''. The institution was granted university ...
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Four Seasons Centre For The Performing Arts
The Four Seasons Centre for the Performing Arts is a 2,071-seat theatre in Toronto, Ontario, Canada, located at the southeast corner of University Avenue and Queen Street West Queen Street is a major east-west thoroughfare in Toronto, Ontario, Canada. It extends from Roncesvalles Avenue and King Street in the west to Victoria Park Avenue in the east. Queen Street was the cartographic baseline for the original east-w ..., across from Osgoode Hall. The land on which it is located was a gift from the Government of Ontario. It is the home of the Canadian Opera Company (COC) and the National Ballet of Canada.Crabb, Michael (November 27, 2016)"Xiao Nan Yu is heart-wrenching in National Ballet’s Onegin: review" ''Toronto Star''. The building's Modern architecture, modernist design by was created by Canadian firm Diamond and Schmitt Architects, headed by Jack Diamond (architect), Jack Diamond. It was completed in 2006, and the interior design includes an unusual glass staircase. H ...
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Cancer Treatment
Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. chemotherapy before surgery). The choice of therapy depends upon the location and grade of the tumor and the stage of the disease, as well as the general state of the patient (performance status). Cancer genome sequencing helps in determining which cancer the patient exactly has for determining the best therapy for the cancer. A number of experimental cancer treatments are also under development. Under current estimates, two in five people will have cancer at some point in their lifetime. Complete removal of the cancer without damage to the rest of the body (that is, achieving cure with near-zero adverse effects) is the ideal, if rarely achieved, goal of treatment and is often the goal in practice. Sometimes this can be accomplished by sur ...
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Cancer Research
Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as cancer immunotherapy and gene therapy. Cancer research is done in academia, research institutes, and corporate environments, and is largely government funded. History Cancer research has been ongoing for centuries. Early research focused on the causes of cancer. Percivall Pott identified the first environmental trigger (chimney soot) for cancer in 1775 and cigarette smoking was identif ...
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Montreal
Montreal ( ; officially Montréal, ) is the List of the largest municipalities in Canada by population, second-most populous city in Canada and List of towns in Quebec, most populous city in the Provinces and territories of Canada, Canadian province of Quebec. Founded in 1642 as ''Fort Ville-Marie, Ville-Marie'', or "City of Mary", it is named after Mount Royal, the triple-peaked hill around which the early city of Ville-Marie is built. The city is centred on the Island of Montreal, which obtained its name from the same origin as the city, and a few much smaller peripheral islands, the largest of which is Île Bizard. The city is east of the national capital Ottawa, and southwest of the provincial capital, Quebec City. As of 2021, the city had a population of 1,762,949, and a Census Metropolitan Area#Census metropolitan areas, metropolitan population of 4,291,732, making it the List of the largest municipalities in Canada by population, second-largest city, and List of cen ...
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Terry Fox
Terrance Stanley Fox (July 28, 1958 June 28, 1981) was a Canadian athlete, humanitarian, and cancer research activist. In 1980, with one leg having been amputated due to cancer, he embarked on an east-to-west cross-Canada run to raise money and awareness for cancer research. Although the spread of his cancer eventually forced him to end his quest after 143 days and , and ultimately cost him his life, his efforts resulted in a lasting, worldwide legacy. The annual Terry Fox Run, first held in 1981, has grown to involve millions of participants in over 60 countries and is now the world's largest one-day fundraiser for cancer research; over C$850 million has been raised in his name as of September 2022. Fox was a distance runner and basketball player for his Port Coquitlam high school, now named after him, and Simon Fraser University. His right leg was amputated in 1977 after he was diagnosed with osteosarcoma, though he continued to run using an artificial leg. He also played ...
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Terry Fox Run
The Terry Fox Run is an annual non-competitive charity event held around the world to raise money for cancer research in commemoration of Canadian cancer activist Terry Fox and his Marathon of Hope. The event was founded in 1981 by Isadore Sharp, who had contacted Terry in hospital by telegram and expressed his wishes to hold an annual run in Terry's name to raise funds for cancer research. Sharp had lost his son to cancer in 1979. The event is held every year on the second Sunday following Labour Day. Since its inception, it has raised via the 'Terry Fox Foundation' over $750 million (CAD). The run is informal which means that the distance often varies, usually between 5 and 15 kilometres; participation is considered to be more important than completing the set distance. There are also runs set up by schools of every level, often with shorter distances than the "official" ones. The Terry Fox Run has no corporate sponsorship, in accordance with Terry Fox's original wishes of not ...
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