Irving Kirsch
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Irving Kirsch
Irving Kirsch (born March 7, 1943) is an American psychologist and academic. He is the Associate Director of the Program in Placebo Studies and a lecturer in medicine at the Harvard Medical School and Beth Israel Deaconess Medical Center. He is also professor emeritus of psychology at the Universities of Hull and Plymouth in the United Kingdom, and the University of Connecticut in the United States. Kirsch is a leading researcher within the field of placebo studies who is noted for his work on placebo effects, antidepressants, expectancy, and hypnosis. He is the originator of response expectancy theory, and his analyses of clinical trials of antidepressants have influenced official treatment guidelines in the United Kingdom. He is the author of the 2009 book '' The Emperor's New Drugs'', which argued most antidepressant medication is effective primarily due to placebo effects. Biography The son of Jewish immigrants from Poland and Russia, Kirsch was born in New York City on ...
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Psychiatry
Psychiatry is the medical specialty devoted to the diagnosis, prevention, and treatment of mental disorders. These include various maladaptations related to mood, behaviour, cognition, and perceptions. See glossary of psychiatry. Initial psychiatric assessment of a person typically begins with a case history and mental status examination. Physical examinations and psychological tests may be conducted. On occasion, neuroimaging or other neurophysiological techniques are used. Mental disorders are often diagnosed in accordance with clinical concepts listed in diagnostic manuals such as the ''International Classification of Diseases'' (ICD), edited and used by the World Health Organization (WHO) and the widely used '' Diagnostic and Statistical Manual of Mental Disorders'' (DSM), published by the American Psychiatric Association (APA). The fifth edition of the DSM (DSM-5) was published in May 2013 which re-organized the larger categories of various diseases and expanded upon the p ...
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New York City
New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the List of United States cities by population density, most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York (state), New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban area, urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous Megacity, megacities, and over 58 million people live within of the city. New York City is a global city, global Culture of New ...
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John Ioannidis
John P. A. Ioannidis (; el, Ιωάννης Ιωαννίδης, ; born August 21, 1965) is a Greek-American physician-scientist, writer and Stanford University professor who has made contributions to evidence-based medicine, epidemiology, and clinical research. Ioannidis studies scientific research itself, meta-research primarily in clinical medicine and the social sciences. He has served on the editorial board of over twenty scientific journals. Ioannidis's 2005 essay "Why Most Published Research Findings Are False" was the most-accessed article in the history of Public Library of Science (PLOS) as of 2020, with more than three million views. Ioannidis has been a prominent opponent of masks and lockdowns during the COVID-19 pandemic. Early life and education Born in New York City in 1965, Ioannidis was raised in Athens, Greece. He was valedictorian of his class at Athens College, graduating in 1984, and won a number of awards, including the National Award of the Greek Mathema ...
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David Healy (psychiatrist)
David Healy, a professor of psychiatry at Bangor University in the United Kingdom, is a psychiatrist, psychopharmacologist, scientist and author. His main areas of research are the contribution of antidepressants to suicide, conflict of interest between pharmaceutical companies and academic medicine, and the history of pharmacology. Healy has written more than 150 peer-reviewed articles, 200 other articles, and 20 books, including ''The Antidepressant Era'', ''The Creation of Psychopharmacology'', ''The Psychopharmacologists Volumes 1–3'', ''Let Them Eat Prozac'' and ''Mania: A Short History of Bipolar Disorder''. Healy has been involved as an expert witness in homicide and suicide trials involving psychotropic drugs, and has brought concerns about some medications to the attention of drug regulators. He has also said that pharmaceutical companies sell drugs by marketing diseases and co-opting academic opinion-leaders. In his 2012 book '' Pharmageddon'' he argues that pharma ...
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British Psychological Society
The British Psychological Society (BPS) is a representative body for psychologists and psychology in the United Kingdom. History It was founded on 24 October 1901 at University College London (UCL) as ''The Psychological Society'', the organisation initially admitted only recognised teachers in the field of psychology. The ten founder members were: * Robert Armstrong-Jones * Sophie Bryant * W.R. Boyce Gibson * Frank Noel Hales * William McDougall * Frederick Walker Mott * William Halse Rivers Rivers * Alexander Faulkner Shand * William George Smith * James Sully Its current name of ''The British Psychological Society'' was taken in 1906 to avoid confusion with another group named ''The Psychological Society''. Under the guidance of Charles Myers, membership was opened up to members of the medical profession in 1919. In 1941 the society was incorporated. Mission The Society aims to raise standards of training and practice in psychology, raise public awareness of p ...
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Cohen's D
In statistics, an effect size is a value measuring the strength of the relationship between two variables in a population, or a sample-based estimate of that quantity. It can refer to the value of a statistic calculated from a sample of data, the value of a parameter for a hypothetical population, or to the equation that operationalizes how statistics or parameters lead to the effect size value. Examples of effect sizes include the correlation between two variables, the regression coefficient in a regression, the mean difference, or the risk of a particular event (such as a heart attack) happening. Effect sizes complement statistical hypothesis testing, and play an important role in power analyses, sample size planning, and in meta-analyses. The cluster of data-analysis methods concerning effect sizes is referred to as estimation statistics. Effect size is an essential component when evaluating the strength of a statistical claim, and it is the first item (magnitude) in the MAGI ...
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National Institute For Health And Clinical Excellence
The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body of the Department of Health and Social Care in England that publishes guidelines in four areas: * the use of health technologies within England's National Health Service (NHS) and NHS Wales (such as the use of new and existing medicines, treatments and procedures) * clinical practice (guidance on the appropriate treatment and care of people with specific diseases and conditions) * guidance for public sector workers on health promotion and ill-health avoidance * guidance for social care services and users. These appraisals are based primarily on evidence-based evaluations of efficacy, safety and cost-effectiveness in various circumstances. It serves both the English NHS and the Welsh NHS. It was set up as the National Institute for Clinical Excellence in 1999, and on 1 April 2005 joined with the Health Development Agency to become the new National Institute for Health a ...
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Size Effect
According to the classical theories of elastic or plastic structures made from a material with non-random strength (''f''t), the nominal strength (''σ''N) of a structure is independent of the structure size (''D'') when geometrically similar structures are considered.The nominal strength of a structure (''σ''N) has units of stress and is related to the maximum load (''P''max) that the structure can support. For structures that can be approximated as two-dimensional, ''σ''N = ''P''max/''bD'' where ''b'' is the thickness of the two-dimensional structure. For three-dimensional structures, ''σ''N = ''P''max/''D''2. Any structure dimension can be chosen for ''D'' but it must be homologous for every size. Any deviation from this property is called the size effect. For example, conventional strength of materials predicts that a large beam and a tiny beam will fail at the same stress if they are made of the same material. In the real world, because of size effects, a larger beam wi ...
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Food And Drug Administration (United States)
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, animal foods & feed and veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not directly related to food or drugs, but involves such things as regulating lasers, cellular phones, and condoms, as well as control of disease in contexts varying fro ...
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Grammy
The Grammy Awards (stylized as GRAMMY), or simply known as the Grammys, are awards presented by the Recording Academy of the United States to recognize "outstanding" achievements in the music industry. They are regarded by many as the most prestigious, significant awards in the music industry worldwide. It was originally called the Gramophone Awards, as the trophy depicts a gilded gramophone. The Grammys are the first of the Big Three networks' major music awards held annually, and is considered one of the four major annual American entertainment awards, alongside the Academy Awards (for films), the Emmy Awards (for television), and the Tony Awards (for theater). The first Grammy Awards ceremony was held on May 4, 1959, to honor the musical accomplishments of performers for the year 1958. After the 2011 ceremony, the Recording Academy overhauled many Grammy Award categories for 2012. History The Grammys had their origin in the Hollywood Walk of Fame project in the 1950s. ...
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Watergate
The Watergate scandal was a major political scandal in the United States involving the administration of President Richard Nixon from 1972 to 1974 that led to Nixon's resignation. The scandal stemmed from the Nixon administration's continual attempts to cover up its involvement in the June 17, 1972, break-in of the Democratic National Committee headquarters at the Washington, D.C., Watergate Office Building. After the five perpetrators were arrested, the press and the Justice Department connected the cash found on them at the time to the Committee for the Re-Election of the President. Further investigations, along with revelations during subsequent trials of the burglars, led the House of Representatives to grant the U.S. House Judiciary Committee additional investigative authority—to probe into "certain matters within its jurisdiction", and led the Senate to create the U.S. Senate Watergate Committee, which held hearings. Witnesses testified that Nixon had approved plans ...
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Richard Nixon
Richard Milhous Nixon (January 9, 1913April 22, 1994) was the 37th president of the United States, serving from 1969 to 1974. A member of the Republican Party, he previously served as a representative and senator from California and was the 36th vice president from 1953 to 1961 under President Dwight D. Eisenhower. His five years in the White House saw reduction of U.S. involvement in the Vietnam War, détente with the Soviet Union and China, the first manned Moon landings, and the establishment of the Environmental Protection Agency and Occupational Safety and Health Administration. Nixon's second term ended early, when he became the only president to resign from office, as a result of the Watergate scandal. Nixon was born into a poor family of Quakers in a small town in Southern California. He graduated from Duke Law School in 1937, practiced law in California, then moved with his wife Pat to Washington in 1942 to work for the federal government. After active duty ...
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