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Ion Transporter Superfamily
The ion transporter (IT) superfamily is a protein superfamily, superfamily of secondary carriers that transport proteins, transport charged substrates. Families As of early 2016, the currently recognized and functionally defined families that make up the IT superfamily include: 2.A.8- Gluconate-Proton symporter, The Gluconate:H+ Symporter (GntP) Family 2.A.11- Citrate symporter, The Citrate-Mg2+:H+ (CitM) Citrate-Ca2+:H+ (CitH) Symporter (CitMHS) Family 2.A.13- C4-dicarboxylate uptake, The C4-Dicarboxylate Uptake (Dcu) Family 2.A.14- Lactate permease, The Lactate Permease (LctP) Family 2.A.34- NhaB family, The NhaB Na+:H+ Antiporter (NhaB) Family 2.A.35- NhaC family, The NhaC Na+:H+ Antiporter (NhaC) Family 2.A.45- ArsB and ArsAB transporters, The Arsenite-Antimonite (ArsB) Efflux Family 2.A.47- Divalent anion-Sodium symporter, The Divalent Anion:Na+ Symporter (DASS) Family 2.A.61- DcuC family, The C4-dicarboxylate Uptake C (DcuC) Family 2.A.62- NhaD family, The NhaD Na+:H+ Anti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Superfamily
A protein superfamily is the largest grouping (clade) of proteins for which common ancestry can be inferred (see homology (biology), homology). Usually this common ancestry is inferred from structural alignment and mechanistic similarity, even if no sequence similarity is evident. Sequence homology can then be deduced even if not apparent (due to low sequence similarity). Superfamilies typically contain several protein families which show sequence similarity within each family. The term ''protein clan'' is commonly used for protease and glycosyl hydrolases superfamilies based on the MEROPS and CAZy classification systems. Identification Superfamilies of proteins are identified using a number of methods. Closely related members can be identified by different methods to those needed to group the most evolutionarily divergent members. Sequence similarity Historically, the similarity of different amino acid sequences has been the most common method of inferring Sequence homology, h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
